Skip to content
Use your HSA or FSA funds

Gene

BICD2

BICD cargo adaptor 2

Summary

Cytogenetic location
9q22.31
Coordinates
Chromosome 9: 92,711,363–92,764,833 (GRCh38)
Exons
7 exons across 53.5 kb
Protein
855 amino acids
Also known as
KIAA0699
MANE Select transcript
ENST00000356884.11NM_001003800.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

  • Spinal Muscular Atrophy

    • A group of disorders characterised by degeneration of spinal cord anterior horn cells, leading to progressive muscle weakness and atrophy.

      • 5 GenCC submitters rate it definitive or strong
      What knowing changes

      Gene therapy (onasemnogene abeparvovec), antisense oligonucleotide therapy (nusinersen), oral splicing modifier (risdiplam), supportive care

How BICD2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 9, with a bracket where BICD2 sits. BICD2 and 14 genes near it on chromosome 9, from 92,238,098 to 93,238,097.Chromosome 99q22.31p24.3p24.2p24.1p23p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q13q21.11q21.12q21.13q21.2q21.31q21.32q21.33q22.1q22.2q22.31q22.32q22.33q31.1q31.2q31.3q32q33.1q33.2q33.3q34.11q34.12q34.13q34.2q34.392.4 Mb92.6 Mb92.8 Mb93 Mb93.2 MbIARS1: 92,210,199–92,293,854, reverse strandIARS1NOL8: 92,297,358–92,325,636, reverse strandNOL8CENPP: 92,325,625–92,620,529, forward strandCENPPOGN: 92,383,268–92,406,734, reverse strandOGNOMD: 92,412,034–92,424,481, reverse strandOMDASPN: 92,456,193–92,492,208, reverse strandASPNECM2: 92,493,554–92,536,736, reverse strandECM2IPPK: 92,612,984–92,670,278, reverse strandIPPKBICD2: 92,711,363–92,764,833, reverse strandBICD2ZNF484: 92,843,171–92,878,050, reverse strandZNF484FGD3: 92,947,410–93,036,238, forward strandFGD3SUSD3: 93,058,684–93,085,141, forward strandSUSD3CARD19: 93,096,153–93,113,284, forward strandCARD19NINJ1: 93,121,495–93,134,612, reverse strandNINJ1WNK2: 93,184,122–93,320,572, forward strandWNK2Diagram of BICD2: 7 exons on the reverse strand of chromosome 9Exon 7: 1 known disease-causing siteExon 6: 4 known disease-causing sitesExon 5: 12 known disease-causing sitesExon 4: 1 known disease-causing siteExon 3: 5 known disease-causing sitesExon 2: 1 known disease-causing siteExon 7: 92,711,363–92,715,463, 4,101 basesExon 6: 92,717,797–92,717,948, 152 basesExon 5: 92,718,539–92,719,582, 1,044 basesExon 4: 92,720,300–92,720,755, 456 basesExon 3: 92,722,656–92,722,808, 153 basesExon 2: 92,729,024–92,729,236, 213 basesExon 1: 92,764,505–92,764,833, 329 bases76543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 6.4 kb of the gene's 53.5 kb; 2,568 of those bases code for the protein.

How a genome test reads BICD2

24

positions in BICD2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 53.5 kb of BICD2, introns included, not only the 6.4 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). BICD2 gene: BICD cargo adaptor 2. Retrieved 16 October 2026, from https://dantelabs.com/genes/bicd2

Vancouver

Dante Labs. BICD2 gene: BICD cargo adaptor 2 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/bicd2

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test