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Trait
Nausea and vomiting
Nausea is a commonly encountered symptom that has been defined as an unpleasant painless subjective feeling that one will imminently vomit. Vomiting has been defined as the forceful expulsion of the contents of the stomach, duodenum, or jejunum through the oral cavity. While nausea and vomiting are often thought to exist on a temporal continuum, this is not always the case. There are situations when severe nausea may be present without emesis and less frequently, when emesis may be present without preceding nausea.
Summary
- Body system
- Abnormality of the digestive system
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This page as data
Add .json to the page's address, or ask for application/json, to read it as JSON.
library(jsonlite)
url <- "https://dantelabs.com/traits/nausea-and-vomiting.json"
page <- fromJSON(url)
page$trait$nameNausea and vomitingHP:0002017
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Read the genes linked to Nausea and vomiting, and the rest of your genome, with one test.
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Get my Genome Test153 genes linked to Nausea and vomiting
Changes in these genes cause rare conditions in which Nausea and vomiting is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ATP9AATPase phospholipid transporting 9A | Always | In 1 condition |
| NOTCH3notch receptor 3 | Always | In 1 condition |
| SLC25A4solute carrier family 25 member 4 | Always | In 1 condition |
| ABCD1ATP binding cassette subfamily D member 1 | Very often (80–99%) | In 1 condition |
| ACTG2actin gamma 2, smooth muscle | Very often (80–99%) | In 1 condition |
| ATP7AATPase copper transporting alpha | Very often (80–99%) | In 2 conditions |
| BCL10BCL10 immune signaling adaptor | Very often (80–99%) | In 1 condition |
| BIRC3baculoviral IAP repeat containing 3 | Very often (80–99%) | In 1 condition |
| BRCA1BRCA1 DNA repair associated | Very often (80–99%) | In 2 conditions |
| C4Acomplement C4A (Chido/Rodgers blood group) | Very often (80–99%) | In 1 condition |
| CCR1C-C motif chemokine receptor 1 | Very often (80–99%) | In 1 condition |
| ECE1endothelin converting enzyme 1 | Very often (80–99%) | In 1 condition |
| EDN3endothelin 3 | Very often (80–99%) | In 1 condition |
| EDNRBendothelin receptor type B | Very often (80–99%) | In 1 condition |
| ERAP1endoplasmic reticulum aminopeptidase 1 | Very often (80–99%) | In 1 condition |
| ERBB2erb-b2 receptor tyrosine kinase 2 | Very often (80–99%) | In 2 conditions |
| ERBB3erb-b2 receptor tyrosine kinase 3 | Very often (80–99%) | In 1 condition |
| FASFas cell surface death receptor | Very often (80–99%) | In 1 condition |
| FOXP1forkhead box P1 | Very often (80–99%) | In 1 condition |
| FSHRfollicle stimulating hormone receptor | Very often (80–99%) | In 1 condition |
| GDNFglial cell derived neurotrophic factor | Very often (80–99%) | In 1 condition |
| HLA-Bmajor histocompatibility complex, class I, B | Very often (80–99%) | In 2 conditions |
| HLCSholocarboxylase synthetase | Very often (80–99%) | In 1 condition |
| IFNGR1interferon gamma receptor 1 | Very often (80–99%) | In 1 condition |
| IGHimmunoglobulin heavy locus | Very often (80–99%) | In 1 condition |
| IKZF1IKAROS family zinc finger 1 | Very often (80–99%) | In 1 condition |
| IL10interleukin 10 | Very often (80–99%) | In 1 condition |
| IL12Ainterleukin 12A | Very often (80–99%) | In 1 condition |
| IL12A-AS1IL12A antisense RNA 1 | Very often (80–99%) | In 1 condition |
| IL23Rinterleukin 23 receptor | Very often (80–99%) | In 1 condition |
| ITGA6integrin subunit alpha 6 | Very often (80–99%) | In 1 condition |
| ITGB4integrin subunit beta 4 | Very often (80–99%) | In 1 condition |
| KLRC4killer cell lectin like receptor C4 | Very often (80–99%) | In 1 condition |
| LIPAlipase A, lysosomal acid type | Very often (80–99%) | In 2 conditions |
| LMOD1leiomodin 1 | Very often (80–99%) | In 1 condition |
| MALT1MALT1 paracaspase | Very often (80–99%) | In 1 condition |
| MEFVMEFV innate immunity regulator, pyrin | Very often (80–99%) | In 2 conditions |
| MMUTmethylmalonyl-CoA mutase | Very often (80–99%) | In 2 conditions |
| MYH11myosin heavy chain 11 | Very often (80–99%) | In 1 condition |
| MYLKmyosin light chain kinase | Very often (80–99%) | In 1 condition |
Show 113 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| NLRP3NLR family pyrin domain containing 3 | Very often (80–99%) | In 2 conditions |
| NRTNneurturin | Very often (80–99%) | In 1 condition |
| PTENphosphatase and tensin homolog | Very often (80–99%) | In 1 condition |
| RETret proto-oncogene | Very often (80–99%) | In 1 condition |
| RHBDF2rhomboid 5 homolog 2 | Very often (80–99%) | In 1 condition |
| SDHAsuccinate dehydrogenase complex flavoprotein subunit A | Very often (80–99%) | In 2 conditions |
| SDHBsuccinate dehydrogenase complex iron sulfur subunit B | Very often (80–99%) | In 2 conditions |
| SDHCsuccinate dehydrogenase complex subunit C | Very often (80–99%) | In 2 conditions |
| SEMA3Csemaphorin 3C | Very often (80–99%) | In 1 condition |
| SEMA3Dsemaphorin 3D | Very often (80–99%) | In 1 condition |
| SLC1A3solute carrier family 1 member 3 | Very often (80–99%) | In 1 condition |
| SLC46A1solute carrier family 46 member 1 | Very often (80–99%) | In 1 condition |
| SMARCB1SWI/SNF related BAF chromatin remodeling complex subunit B1 | Very often (80–99%) | In 2 conditions |
| SMOsmoothened, frizzled class receptor | Very often (80–99%) | In 2 conditions |
| SREBF1sterol regulatory element binding transcription factor 1 | Very often (80–99%) | In 1 condition |
| STAT4signal transducer and activator of transcription 4 | Very often (80–99%) | In 1 condition |
| TLR4toll like receptor 4 | Very often (80–99%) | In 1 condition |
| UBAC2UBA domain containing 2 | Very often (80–99%) | In 1 condition |
| AIPAHR interacting HSP90 co-chaperone | Often (30–79%) | In 1 condition |
| AKT1AKT serine/threonine kinase 1 | Often (30–79%) | In 1 condition |
| AQP2aquaporin 2 | Often (30–79%) | In 1 condition |
| ATMATM serine/threonine kinase | Often (30–79%) | In 1 condition |
| ATRXATRX chromatin remodeler | Often (30–79%) | In 2 conditions |
| AVPR2arginine vasopressin receptor 2 | Often (30–79%) | In 1 condition |
| BAP1BRCA1 associated deubiquitinase 1 | Often (30–79%) | In 1 condition |
| BAZ1Bbromodomain adjacent to zinc finger domain 1B | Often (30–79%) | In 1 condition |
| BMPR1Abone morphogenetic protein receptor type 1A | Often (30–79%) | In 1 condition |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Often (30–79%) | In 1 condition |
| BRCA2BRCA2 DNA repair associated | Often (30–79%) | In 2 conditions |
| BUD23BUD23 rRNA methyltransferase and ribosome maturation factor | Often (30–79%) | In 1 condition |
| CACNA1Acalcium voltage-gated channel subunit alpha1 A | Often (30–79%) | In 2 conditions |
| CAV1caveolin 1 | Often (30–79%) | In 2 conditions |
| CCN2cellular communication network factor 2 | Often (30–79%) | In 2 conditions |
| CCR6C-C motif chemokine receptor 6 | Often (30–79%) | In 2 conditions |
| CDH23cadherin related 23 | Often (30–79%) | In 2 conditions |
| CHEK2checkpoint kinase 2 | Often (30–79%) | In 1 condition |
| CLIP2CAP-Gly domain containing linker protein 2 | Often (30–79%) | In 1 condition |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Often (30–79%) | In 1 condition |
| CTNNB1catenin beta 1 | Often (30–79%) | In 1 condition |
| DLEC1DLEC1 cilia and flagella associated protein | Often (30–79%) | In 1 condition |
| DNAJC30DnaJ heat shock protein family (Hsp40) member C30 | Often (30–79%) | In 1 condition |
| DNASE1L3deoxyribonuclease 1L3 | Often (30–79%) | In 1 condition |
| EIF4Heukaryotic translation initiation factor 4H | Often (30–79%) | In 1 condition |
| ELNelastin | Often (30–79%) | In 1 condition |
| EPCAMepithelial cell adhesion molecule | Often (30–79%) | In 1 condition |
| EWSR1EWS RNA binding protein 1 | Often (30–79%) | In 1 condition |
| FKBP6FKBP prolyl isomerase family member 6 (inactive) | Often (30–79%) | In 1 condition |
| GATA2GATA binding protein 2 | Often (30–79%) | In 1 condition |
| GLAgalactosidase alpha | Often (30–79%) | In 1 condition |
| GTF2Igeneral transcription factor IIi | Often (30–79%) | In 1 condition |
| GTF2IRD1GTF2I repeat domain containing 1 | Often (30–79%) | In 1 condition |
| GTF2IRD2GTF2I repeat domain containing 2 | Often (30–79%) | In 1 condition |
| HLA-DPA1major histocompatibility complex, class II, DP alpha 1 | Often (30–79%) | In 1 condition |
| HLA-DPB1major histocompatibility complex, class II, DP beta 1 | Often (30–79%) | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Often (30–79%) | In 2 conditions |
| HMBShydroxymethylbilane synthase | Often (30–79%) | In 1 condition |
| IRF5interferon regulatory factor 5 | Often (30–79%) | In 2 conditions |
| KIAA0319LKIAA0319 like | Often (30–79%) | In 1 condition |
| KITKIT proto-oncogene, receptor tyrosine kinase | Often (30–79%) | In 1 condition |
| KRASKRas proto-oncogene, GTPase | Often (30–79%) | In 2 conditions |
| LIMK1LIM domain kinase 1 | Often (30–79%) | In 1 condition |
| MEN1menin 1 | Often (30–79%) | In 1 condition |
| METTL27methyltransferase like 27 | Often (30–79%) | In 1 condition |
| MLH1mutL homolog 1 | Often (30–79%) | In 1 condition |
| MSH2mutS homolog 2 | Often (30–79%) | In 1 condition |
| MSH6mutS homolog 6 | Often (30–79%) | In 1 condition |
| MUTYHmutY DNA glycosylase | Often (30–79%) | In 1 condition |
| NCF1neutrophil cytosolic factor 1 | Often (30–79%) | In 1 condition |
| NF2NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor | Often (30–79%) | In 1 condition |
| NPATnuclear protein, coactivator of histone transcription | Often (30–79%) | In 1 condition |
| PDGFBplatelet derived growth factor subunit B | Often (30–79%) | In 1 condition |
| PDGFRAplatelet derived growth factor receptor alpha | Often (30–79%) | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Often (30–79%) | In 2 conditions |
| PMS1PMS1 homolog 1, mismatch repair system component | Often (30–79%) | In 1 condition |
| PMS2PMS1 homolog 2, mismatch repair system component | Often (30–79%) | In 1 condition |
| POLD1DNA polymerase delta 1, catalytic subunit | Often (30–79%) | In 1 condition |
| POLEDNA polymerase epsilon, catalytic subunit | Often (30–79%) | In 1 condition |
| PRTN3proteinase 3 | Often (30–79%) | In 1 condition |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Often (30–79%) | In 1 condition |
| RFC2replication factor C subunit 2 | Often (30–79%) | In 1 condition |
| RNF6ring finger protein 6 | Often (30–79%) | In 1 condition |
| RPS20ribosomal protein S20 | Often (30–79%) | In 1 condition |
| SEMA4Asemaphorin 4A | Often (30–79%) | In 1 condition |
| SMARCE1SWI/SNF related BAF chromatin remodeling complex subunit E1 | Often (30–79%) | In 1 condition |
| STX1Asyntaxin 1A | Often (30–79%) | In 1 condition |
| SUFUSUFU negative regulator of hedgehog signaling | Often (30–79%) | In 1 condition |
| TBK1TANK binding kinase 1 | Often (30–79%) | In 1 condition |
| TBL2transducin beta like 2 | Often (30–79%) | In 1 condition |
| TERTtelomerase reverse transcriptase | Often (30–79%) | In 1 condition |
| TGFBR2transforming growth factor beta receptor 2 | Often (30–79%) | In 2 conditions |
| TICAM1TIR domain containing adaptor molecule 1 | Often (30–79%) | In 1 condition |
| TLR3toll like receptor 3 | Often (30–79%) | In 1 condition |
| TMEM270transmembrane protein 270 | Often (30–79%) | In 1 condition |
| TRAF3TNF receptor associated factor 3 | Often (30–79%) | In 1 condition |
| TRAF7TNF receptor associated factor 7 | Often (30–79%) | In 1 condition |
| TRMT5tRNA methyltransferase 5 | Often (30–79%) | In 1 condition |
| UNC93B1unc-93B1 regulator of TLR signaling | Often (30–79%) | In 1 condition |
| VPS37DVPS37D subunit of ESCRT-I | Often (30–79%) | In 1 condition |
| WT1WT1 transcription factor | Often (30–79%) | In 1 condition |
| WWOXWW domain containing oxidoreductase | Often (30–79%) | In 1 condition |
| CDC73cell division cycle 73 | Sometimes (5–29%) | In 2 conditions |
| CDKN2Acyclin dependent kinase inhibitor 2A | Sometimes (5–29%) | In 1 condition |
| CLCNKBchloride voltage-gated channel Kb | Sometimes (5–29%) | In 1 condition |
| FLI1Fli-1 proto-oncogene, ETS transcription factor | Sometimes (5–29%) | In 1 condition |
| MYCMYC proto-oncogene, bHLH transcription factor | Sometimes (5–29%) | In 1 condition |
| PALB2partner and localizer of BRCA2 | Sometimes (5–29%) | In 1 condition |
| PALLDpalladin, cytoskeletal associated protein | Sometimes (5–29%) | In 1 condition |
| RAB27ARAB27A, member RAS oncogene family | Sometimes (5–29%) | In 1 condition |
| RABL3RAB, member of RAS oncogene family like 3 | Sometimes (5–29%) | In 1 condition |
| SDHDsuccinate dehydrogenase complex subunit D | Sometimes (5–29%) | In 1 condition |
| SLC12A3solute carrier family 12 member 3 | Sometimes (5–29%) | In 1 condition |
| SMAD4SMAD family member 4 | Sometimes (5–29%) | In 1 condition |
| TP53tumor protein p53 | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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