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Gene

TRAF3

TNF receptor associated factor 3

Summary

Cytogenetic location
14q32.32
Coordinates
Chromosome 14: 102,777,449–102,911,500 (GRCh38)
Exons
12 exons across 134.1 kb
Protein
568 amino acids
Also known as
CAP-1, CD40bp, CRAF1, LAP1, RNF118
MANE Select transcript
ENST00000392745.8NM_145725.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TRAF3 yet. The test sequences your whole genome, so your data includes it all the same.

How TRAF3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 14, with a bracket where TRAF3 sits. TRAF3 and 12 genes near it on chromosome 14, from 102,344,475 to 103,344,474.Chromosome 1414q32.32p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.11q32.12q32.13q32.2q32.31q32.32q32.33102.4 Mb102.6 Mb102.8 Mb103 Mb103.2 MbZNF839: 102,317,377–102,344,638, forward strandZNF839CINP: 102,341,102–102,362,916, reverse strandCINPTECPR2: 102,362,933–102,502,477, forward strandTECPR2ANKRD9: 102,501,767–102,509,824, reverse strandANKRD9RCOR1: 102,592,649–102,743,672, forward strandRCOR1TRAF3: 102,777,449–102,911,500, forward strandTRAF3AMN: 102,922,639–102,933,596, forward strandAMNCDC42BPB: 102,932,380–103,057,607, reverse strandCDC42BPBLBHD2: 103,084,174–103,090,031, forward strandLBHD2EXOC3L4: 103,094,538–103,110,571, forward strandEXOC3L4TNFAIP2: 103,121,265–103,137,441, forward strandTNFAIP2EIF5: 103,333,544–103,345,025, forward strandEIF5: 103,334,237–103,335,932, forward strandDiagram of TRAF3: 12 exons on the forward strand of chromosome 14Exon 11: 1 known disease-causing siteExon 12: 1 known disease-causing siteExon 1: 102,777,449–102,777,675, 227 basesExon 2: 102,830,334–102,830,472, 139 basesExon 3: 102,870,185–102,870,446, 262 basesExon 4: 102,871,917–102,871,968, 52 basesExon 5: 102,875,624–102,875,728, 105 basesExon 6: 102,876,358–102,876,525, 168 basesExon 7: 102,886,189–102,886,269, 81 basesExon 8: 102,889,560–102,889,634, 75 basesExon 9: 102,891,325–102,891,417, 93 basesExon 10: 102,897,261–102,897,401, 141 basesExon 11: 102,903,255–102,903,429, 175 basesExon 12: 102,905,213–102,911,500, 6,288 bases1246810125′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.8 kb of the gene's 134.1 kb; 1,707 of those bases code for the protein.

How a genome test reads TRAF3

2

positions in TRAF3 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 134.1 kb of TRAF3, introns included, not only the 7.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). TRAF3 gene: TNF receptor associated factor 3. Retrieved 16 October 2026, from https://dantelabs.com/genes/traf3

Vancouver

Dante Labs. TRAF3 gene: TNF receptor associated factor 3 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/traf3

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