Trait
Photosensitive skin
Clinical name: Cutaneous photosensitivity
An increased sensitivity of the skin to light. Photosensitivity may result in a rash upon exposure to the sun (which is known as photodermatosis). Photosensitivity can be diagnosed by phototests in which light is shone on small areas of skin.
Summary
- Also called
- Photosensitive skin rashes, Photosensitivity, Sensitivity to sunlight, Skin photosensitivity, Sun sensitivity
- Body system
- Abnormality of the integument
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Photosensitive skin, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test120 genes linked to Photosensitive skin
Changes in these genes cause rare conditions in which Photosensitive skin is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CLPXcaseinolytic mitochondrial matrix peptidase chaperone subunit X | Always | In 1 condition |
| DNA2DNA replication helicase/nuclease 2 | Always | In 1 condition |
| ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit | Always | In 7 conditions |
| ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit | Always | In 5 conditions |
| ERCC4ERCC excision repair 4, endonuclease catalytic subunit | Always | In 5 conditions |
| ERCC5ERCC excision repair 5, endonuclease | Always | In 5 conditions |
| ERCC6ERCC excision repair 6, chromatin remodeling factor | Always | In 6 conditions |
| ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit | Always | In 4 conditions |
| FDFT1farnesyl-diphosphate farnesyltransferase 1 | Always | In 1 condition |
| FDXRferredoxin reductase | Always | In 1 condition |
| GABRA1gamma-aminobutyric acid type A receptor subunit alpha1 | Always | In 1 condition |
| GTF2H4general transcription factor IIH subunit 4 | Always | In 1 condition |
| GTF2H5general transcription factor IIH subunit 5 | Always | In 2 conditions |
| IKZF2IKAROS family zinc finger 2 | Always | In 1 condition |
| PCNAproliferating cell nuclear antigen | Always | In 2 conditions |
| PLD4phospholipase D family member 4 | Always | In 1 condition |
| POLHDNA polymerase eta | Always | In 2 conditions |
| PPOXprotoporphyrinogen oxidase | Always | In 3 conditions |
| RECQLRecQ like helicase | Always | In 1 condition |
| RNU2-2RNA, U2 small nuclear 2 | Always | In 1 condition |
| SLC6A19solute carrier family 6 member 19 | Always | In 2 conditions |
| URODuroporphyrinogen decarboxylase | Always | In 1 condition |
| XPAXPA, DNA damage recognition and repair factor | Always | In 2 conditions |
| CLTRNcollectrin, amino acid transport regulator | Very often (80–99%) | In 1 condition |
| CYBAcytochrome b-245 alpha chain | Very often (80–99%) | In 1 condition |
| CYBBcytochrome b-245 beta chain | Very often (80–99%) | In 1 condition |
| CYBC1cytochrome b-245 chaperone 1 | Very often (80–99%) | In 1 condition |
| DDB2damage specific DNA binding protein 2 | Very often (80–99%) | In 2 conditions |
| FECHferrochelatase | Very often (80–99%) | In 1 condition |
| FERMT1FERM domain containing kindlin 1 | Very often (80–99%) | In 2 conditions |
| GJA1gap junction protein alpha 1 | Very often (80–99%) | In 1 condition |
| GJB3gap junction protein beta 3 | Very often (80–99%) | In 1 condition |
| GJB4gap junction protein beta 4 | Very often (80–99%) | In 1 condition |
| KDSR3-ketodihydrosphingosine reductase | Very often (80–99%) | In 1 condition |
| NCF1neutrophil cytosolic factor 1 | Very often (80–99%) | In 1 condition |
| NCF2neutrophil cytosolic factor 2 | Very often (80–99%) | In 1 condition |
| NCF4neutrophil cytosolic factor 4 | Very often (80–99%) | In 1 condition |
| PEPDpeptidase D | Very often (80–99%) | In 1 condition |
| XPCXPC complex subunit, DNA damage recognition and repair factor | Very often (80–99%) | In 2 conditions |
| ABCB6ATP binding cassette subfamily B member 6 (LAN blood group) | Often (30–79%) | In 1 condition |
Show 80 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| BLMBLM RecQ like helicase | Often (30–79%) | In 2 conditions |
| CARMIL2capping protein regulator and myosin 1 linker 2 | Often (30–79%) | In 1 condition |
| COL7A1collagen type VII alpha 1 chain | Often (30–79%) | In 1 condition |
| DHCR77-dehydrocholesterol reductase | Often (30–79%) | In 1 condition |
| DNASE1deoxyribonuclease 1 | Often (30–79%) | In 2 conditions |
| ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit | Often (30–79%) | In 1 condition |
| FCGR2AFc gamma receptor IIa | Often (30–79%) | In 1 condition |
| FCGR2BFc gamma receptor IIb | Often (30–79%) | In 2 conditions |
| FDPSfarnesyl diphosphate synthase | Often (30–79%) | In 1 condition |
| HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2 | Often (30–79%) | In 1 condition |
| KRT1keratin 1 | Often (30–79%) | In 1 condition |
| KRT10keratin 10 | Often (30–79%) | In 1 condition |
| LIG4DNA ligase 4 | Often (30–79%) | In 2 conditions |
| LYSTlysosomal trafficking regulator | Often (30–79%) | In 1 condition |
| MAGEL2MAGE family member L2 | Often (30–79%) | In 1 condition |
| MKRN3makorin ring finger protein 3 | Often (30–79%) | In 1 condition |
| MVDmevalonate diphosphate decarboxylase | Often (30–79%) | In 1 condition |
| MVKmevalonate kinase | Often (30–79%) | In 2 conditions |
| NPAP1nuclear pore associated protein 1 | Often (30–79%) | In 1 condition |
| PMVKphosphomevalonate kinase | Often (30–79%) | In 1 condition |
| PORCNporcupine O-acyltransferase | Often (30–79%) | In 1 condition |
| PWAR1Prader Willi/Angelman region RNA 1 | Often (30–79%) | In 1 condition |
| PWRN1Prader-Willi region non-protein coding RNA 1 | Often (30–79%) | In 1 condition |
| SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 | Often (30–79%) | In 1 condition |
| SLC17A9solute carrier family 17 member 9 | Often (30–79%) | In 1 condition |
| SNORD115-1small nucleolar RNA, C/D box 115-1 | Often (30–79%) | In 1 condition |
| SNORD116-1small nucleolar RNA, C/D box 116-1 | Often (30–79%) | In 1 condition |
| TREX1three prime repair exonuclease 1 | Often (30–79%) | In 2 conditions |
| AARS1alanyl-tRNA synthetase 1 | Sometimes (5–29%) | In 1 condition |
| BANK1B cell scaffold protein with ankyrin repeats 1 | Sometimes (5–29%) | In 1 condition |
| BLKBLK proto-oncogene, Src family tyrosine kinase | Sometimes (5–29%) | In 1 condition |
| C4Acomplement C4A (Chido/Rodgers blood group) | Sometimes (5–29%) | In 2 conditions |
| C4Bcomplement C4B (Chido/Rodgers blood group) | Sometimes (5–29%) | In 1 condition |
| CARS1cysteinyl-tRNA synthetase 1 | Sometimes (5–29%) | In 1 condition |
| CPOXcoproporphyrinogen oxidase | Sometimes (5–29%) | In 3 conditions |
| CR2complement C3d receptor 2 | Sometimes (5–29%) | In 1 condition |
| CSTBcystatin B | Sometimes (5–29%) | In 1 condition |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Sometimes (5–29%) | In 1 condition |
| DBR1debranching RNA lariats 1 | Sometimes (5–29%) | In 1 condition |
| DDX6DEAD-box helicase 6 | Sometimes (5–29%) | In 1 condition |
| ETS1ETS proto-oncogene 1, transcription factor | Sometimes (5–29%) | In 1 condition |
| FCGR3BFc gamma receptor IIIb | Sometimes (5–29%) | In 1 condition |
| GTF2E2general transcription factor IIE subunit 2 | Sometimes (5–29%) | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Sometimes (5–29%) | In 1 condition |
| IGHG1immunoglobulin heavy constant gamma 1 (G1m marker) | Sometimes (5–29%) | In 1 condition |
| IL10interleukin 10 | Sometimes (5–29%) | In 1 condition |
| IRAK1interleukin 1 receptor associated kinase 1 | Sometimes (5–29%) | In 1 condition |
| IRF5interferon regulatory factor 5 | Sometimes (5–29%) | In 1 condition |
| ITGAMintegrin subunit alpha M | Sometimes (5–29%) | In 1 condition |
| JAZF1JAZF zinc finger 1 | Sometimes (5–29%) | In 1 condition |
| KCTD1potassium channel tetramerization domain containing 1 | Sometimes (5–29%) | In 1 condition |
| KIAA0319LKIAA0319 like | Sometimes (5–29%) | In 1 condition |
| KRT14keratin 14 | Sometimes (5–29%) | In 1 condition |
| KRT5keratin 5 | Sometimes (5–29%) | In 1 condition |
| MECP2methyl-CpG binding protein 2 | Sometimes (5–29%) | In 1 condition |
| MPLKIPM-phase specific PLK1 interacting protein | Sometimes (5–29%) | In 1 condition |
| NBNnibrin | Sometimes (5–29%) | In 1 condition |
| PDCD1programmed cell death 1 | Sometimes (5–29%) | In 1 condition |
| PRICKLE1prickle planar cell polarity protein 1 | Sometimes (5–29%) | In 1 condition |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Sometimes (5–29%) | In 1 condition |
| PXKPX domain containing serine/threonine kinase like | Sometimes (5–29%) | In 1 condition |
| RNF113Aring finger protein 113A | Sometimes (5–29%) | In 2 conditions |
| SCARB2scavenger receptor class B member 2 | Sometimes (5–29%) | In 1 condition |
| SPP1secreted phosphoprotein 1 | Sometimes (5–29%) | In 1 condition |
| STAT4signal transducer and activator of transcription 4 | Sometimes (5–29%) | In 1 condition |
| SYNGAP1synaptic Ras GTPase activating protein 1 | Sometimes (5–29%) | In 1 condition |
| TARS1threonyl-tRNA synthetase 1 | Sometimes (5–29%) | In 1 condition |
| TLR7toll like receptor 7 | Sometimes (5–29%) | In 1 condition |
| TNFAIP3TNF alpha induced protein 3 | Sometimes (5–29%) | In 1 condition |
| TNFSF4TNF superfamily member 4 | Sometimes (5–29%) | In 1 condition |
| TNIP1TNFAIP3 interacting protein 1 | Sometimes (5–29%) | In 1 condition |
| UBE2L3ubiquitin conjugating enzyme E2 L3 | Sometimes (5–29%) | In 1 condition |
| ALAS25'-aminolevulinate synthase 2 | Not recorded | In 1 condition |
| EPM2AEPM2A glucan phosphatase, laforin | Not recorded | In 1 condition |
| IFIH1interferon induced with helicase C domain 1 | Not recorded | In 1 condition |
| RECQL4RecQ like helicase 4 | Not recorded | In 1 condition |
| RORBRAR related orphan receptor B | Not recorded | In 1 condition |
| TP63tumor protein p63 | Not recorded | In 1 condition |
| UROSuroporphyrinogen III synthase | Not recorded | In 1 condition |
| UVSSAUV stimulated scaffold protein A | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks