Skip to content
Use your HSA or FSA funds

Gene

ABCB6

ATP binding cassette subfamily B member 6 (LAN blood group)

Summary

Cytogenetic location
2q35
Coordinates
Chromosome 2: 219,209,772–219,218,958 (GRCh38)
Exons
19 exons across 9.2 kb
Protein
842 amino acids
Also known as
EST45597, umat, MTABC3
MANE Select transcript
ENST00000265316.9NM_005689.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ABCB6 yet. The test sequences your whole genome, so your data includes it all the same.

How ABCB6 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 2, with a bracket where ABCB6 sits. ABCB6 and 39 genes near it on chromosome 2, from 218,714,365 to 219,714,364.Chromosome 22q35p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.3218.8 Mb219 Mb219.2 Mb219.4 Mb219.6 MbTTLL4: 218,710,773–218,759,724, forward strandTTLL4CYP27A1: 218,781,688–218,825,335, forward strandCYP27A1PRKAG3: 218,819,050–218,832,086, reverse strandPRKAG3WNT6: 218,859,795–218,874,233, forward strandWNT6WNT10A: 218,880,852–218,899,581, forward strandWNT10ACDK5R2: 218,959,666–218,962,155, forward strandCDK5R2FEV: 218,981,087–218,985,566, reverse strandFEVCRYBA2: 218,990,189–218,994,270, reverse strandCRYBA2CFAP65: 219,002,846–219,041,527, reverse strandCFAP65IHH: 219,054,424–219,061,064, reverse strandIHHNHEJ1: 219,069,355–219,160,869, reverse strandNHEJ1: 219,075,329–219,170,827, reverse strandSLC23A3: 219,161,465–219,170,095, reverse strandCNPPD1: 219,170,704–219,182,664, reverse strandRETREG2: 219,176,225–219,185,917, forward strandZFAND2B: 219,195,237–219,209,651, forward strandZFAND2BABCB6: 219,209,772–219,218,958, reverse strandABCB6: 219,209,772–219,222,738, reverse strandATG9A: 219,219,380–219,230,383, reverse strandATG9AANKZF1: 219,229,769–219,236,679, forward strandGLB1L: 219,236,598–219,245,478, reverse strandSTK16: 219,245,212–219,250,339, forward strandTUBA4A: 219,249,710–219,277,902, reverse strandTUBA4B: 219,253,243–219,272,197, forward strandDNAJB2: 219,279,308–219,286,900, forward strandDNAJB2PTPRN: 219,289,623–219,309,648, reverse strandPTPRNRESP18: 219,327,407–219,335,552, reverse strandRESP18DNPEP: 219,360,090–219,400,022, reverse strandDNPEPDES: 219,417,474–219,426,740, forward strandDESSPEG: 219,434,471–219,493,629, forward strandSPEG: 219,491,867–219,498,244, forward strandSPEGNB: 219,496,129–219,498,287, forward strandSPEGNBGMPPA: 219,498,618–219,513,898, forward strandGMPPAASIC4: 219,514,170–219,538,772, forward strandASIC4CHPF: 219,538,949–219,543,818, reverse strandCHPFTMEM198: 219,543,130–219,550,595, forward strandOBSL1: 219,550,727–219,572,076, reverse strandOBSL1INHA: 219,569,162–219,575,711, forward strandSTK11IP: 219,595,805–219,616,452, forward strandSTK11IPSLC4A3: 219,627,011–219,641,982, forward strandSLC4A3Diagram of ABCB6: 19 exons on the reverse strand of chromosome 2Exon 5: 1 known disease-causing siteExon 19: 219,209,772–219,210,046, 275 basesExon 18: 219,210,230–219,210,298, 69 basesExon 17: 219,210,381–219,210,475, 95 basesExon 16: 219,210,711–219,210,823, 113 basesExon 15: 219,210,934–219,211,108, 175 basesExon 14: 219,212,387–219,212,491, 105 basesExon 13: 219,213,008–219,213,065, 58 basesExon 12: 219,213,241–219,213,326, 86 basesExon 11: 219,213,439–219,213,502, 64 basesExon 10: 219,213,590–219,213,666, 77 basesExon 9: 219,213,826–219,213,951, 126 basesExon 8: 219,214,121–219,214,186, 66 basesExon 7: 219,214,389–219,214,498, 110 basesExon 6: 219,214,961–219,215,082, 122 basesExon 5: 219,215,997–219,216,180, 184 basesExon 4: 219,216,364–219,216,465, 102 basesExon 3: 219,216,652–219,216,832, 181 basesExon 2: 219,217,670–219,217,807, 138 basesExon 1: 219,218,125–219,218,958, 834 bases191816141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3 kb of the gene's 9.2 kb; 2,529 of those bases code for the protein.

How a genome test reads ABCB6

2

positions in ABCB6 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 9.2 kb of ABCB6, introns included, not only the 3 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ABCB6 gene: ATP binding cassette subfamily B member 6 (LAN blood group). Retrieved 16 October 2026, from https://dantelabs.com/genes/abcb6

Vancouver

Dante Labs. ABCB6 gene: ATP binding cassette subfamily B member 6 (LAN blood group) [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/abcb6

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test