Skip to content
Use your HSA or FSA funds

Gene

PRKAR1B

protein kinase cAMP-dependent type I regulatory subunit beta

Summary

Cytogenetic location
7p22.3
Coordinates
Chromosome 7: 549,198–727,281 (GRCh38)
Exons
11 exons across 178.1 kb
Protein
381 amino acids
MANE Select transcript
ENST00000537384.6NM_001164760.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PRKAR1B yet. The test sequences your whole genome, so your data includes it all the same.

How PRKAR1B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 7, with a bracket where PRKAR1B sits. PRKAR1B and 13 genes near it on chromosome 7, from 138,240 to 1,138,239.Chromosome 77p22.3p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.30.2 Mb0.4 Mb0.6 Mb0.8 Mb1 MbFAM20C: 192,034–260,773, forward strandFAM20CFOXL3: 290,170–294,422, forward strandFOXL3PDGFA: 497,258–520,705, reverse strandPDGFAPRKAR1B: 549,198–727,281, reverse strandPRKAR1BDNAAF5: 726,687–790,035, forward strandDNAAF5SUN1: 816,591–896,435, forward strandSUN1GET4: 876,486–896,441, forward strandGET4ADAP1: 896,338–955,407, reverse strandADAP1: 898,778–975,549, reverse strandCOX19: 964,852–975,549, reverse strandCOX19CHLSN: 979,163–1,138,313, reverse strandCHLSNCYP2W1: 983,176–989,640, forward strandCYP2W1GPR146: 1,044,537–1,059,275, forward strandGPR146GPER1: 1,082,208–1,094,516, forward strandGPER1Diagram of PRKAR1B: 11 exons on the reverse strand of chromosome 7Exon 11: 1 known disease-causing siteExon 7: 1 known disease-causing siteExon 11: 549,198–550,602, 1,405 basesExon 10: 551,389–551,470, 82 basesExon 9: 579,256–579,377, 122 basesExon 8: 584,508–584,568, 61 basesExon 7: 596,146–596,304, 159 basesExon 6: 606,193–606,239, 47 basesExon 5: 607,391–607,452, 62 basesExon 4: 677,229–677,320, 92 basesExon 3: 680,556–680,726, 171 basesExon 2: 711,329–711,527, 199 basesExon 1: 727,210–727,281, 72 bases1115′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.5 kb of the gene's 178.1 kb; 1,146 of those bases code for the protein.

How a genome test reads PRKAR1B

2

positions in PRKAR1B where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 178.1 kb of PRKAR1B, introns included, not only the 2.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). PRKAR1B gene: protein kinase cAMP-dependent type I regulatory subunit beta. Retrieved 16 October 2026, from https://dantelabs.com/genes/prkar1b

Vancouver

Dante Labs. PRKAR1B gene: protein kinase cAMP-dependent type I regulatory subunit beta [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/prkar1b

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test