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Gene

MICU1

mitochondrial calcium uptake 1

Summary

Cytogenetic location
10q22.1
Coordinates
Chromosome 10: 72,367,340–72,626,079 (GRCh38)
Exons
12 exons across 258.7 kb
Protein
476 amino acids
Also known as
CALC, EFHA3, FLJ12684
Previous symbols
CBARA1
MANE Select transcript
ENST00000361114.10NM_001195518.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads MICU1 yet. The test sequences your whole genome, so your data includes it all the same.

How MICU1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 10, with a bracket where MICU1 sits. MICU1 and 9 genes near it on chromosome 10, from 71,996,710 to 72,996,709.Chromosome 1010q22.1p15.3p15.2p15.1p14p13p12.33p12.32p12.31p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.31q23.32q23.33q24.1q24.2q24.31q24.32q24.33q25.1q25.2q25.3q26.11q26.12q26.13q26.2q26.372 Mb72.2 Mb72.4 Mb72.6 Mb72.8 MbCHST3: 71,963,538–72,019,147, forward strandCHST3SPOCK2: 72,059,016–72,089,032, reverse strandSPOCK2ASCC1: 72,092,153–72,217,653, reverse strandASCC1ANAPC16: 72,215,651–72,235,860, forward strandANAPC16DDIT4: 72,273,919–72,276,039, forward strandDDIT4DNAJB12: 72,332,830–72,355,167, reverse strandDNAJB12MICU1: 72,367,340–72,626,079, reverse strandMICU1MCU: 72,692,088–72,887,694, forward strandMCUOIT3: 72,893,573–72,933,036, forward strandOIT3PLA2G12B: 72,913,141–72,954,885, reverse strandPLA2G12BDiagram of MICU1: 12 exons on the reverse strand of chromosome 10Exon 9: 1 known disease-causing siteExon 8: 1 known disease-causing siteExon 6: 1 known disease-causing siteExon 4: 3 known disease-causing sitesExon 3: 2 known disease-causing sitesExon 2: 3 known disease-causing sitesExon 12: 72,367,340–72,368,355, 1,016 basesExon 11: 72,375,783–72,375,872, 90 basesExon 10: 72,407,929–72,408,037, 109 basesExon 9: 72,423,234–72,423,371, 138 basesExon 8: 72,475,100–72,475,297, 198 basesExon 7: 72,477,174–72,477,256, 83 basesExon 6: 72,508,155–72,508,269, 115 basesExon 5: 72,533,746–72,533,789, 44 basesExon 4: 72,551,179–72,551,341, 163 basesExon 3: 72,562,895–72,563,063, 169 basesExon 2: 72,566,633–72,566,794, 162 basesExon 1: 72,626,010–72,626,079, 70 bases1210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.4 kb of the gene's 258.7 kb; 1,431 of those bases code for the protein.

How a genome test reads MICU1

15

positions in MICU1 where ClinVar classes a change as pathogenic or likely pathogenic

1 of them (6.7%) falls in a region short reads find hard.

  • Low mappability (1 site)Regions where 100 bp or 250 bp reads cannot be placed uniquely.

A whole genome covers all 258.7 kb of MICU1, introns included, not only the 2.4 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). MICU1 gene: mitochondrial calcium uptake 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/micu1

Vancouver

Dante Labs. MICU1 gene: mitochondrial calcium uptake 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/micu1

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