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Gene

SLC13A5

solute carrier family 13 member 5

Summary

Cytogenetic location
17p13.1
Coordinates
Chromosome 17: 6,684,719–6,713,369 (GRCh38)
Exons
12 exons across 28.7 kb
Protein
568 amino acids
Also known as
NACT, INDY, mINDY
MANE Select transcript
ENST00000433363.7NM_177550.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

    • Epilepsy (Full Panel)

      • Epilepsy

        One of 171 genes linked to it

        A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions.

        • 3 GenCC submitters rate it definitive or strong

    How SLC13A5 is laid out

    • Coding sequence
    • Untranslated region
    • Intron
    • Direction of transcription
    • Known disease-causing sites
    • Stretches short reads find hard
    Chromosome 17, with a bracket where SLC13A5 sits. SLC13A5 and 22 genes near it on chromosome 17, from 6,199,044 to 7,199,043.Chromosome 1717p13.1p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.36.2 Mb6.4 Mb6.6 Mb6.8 Mb7 MbAIPL1: 6,393,693–6,435,199, reverse strandAIPL1PIMREG: 6,443,544–6,451,469, forward strandPIMREGPITPNM3: 6,451,263–6,556,567, reverse strandPITPNM3KIAA0753: 6,578,031–6,640,741, reverse strandKIAA0753: 6,578,031–6,640,711, reverse strandTXNDC17: 6,640,712–6,646,374, forward strandTXNDC17MED31: 6,643,311–6,652,290, reverse strandMED31C17orf100: 6,651,762–6,693,202, forward strandC17orf100SLC13A5: 6,684,719–6,713,369, reverse strandSLC13A5XAF1: 6,755,375–6,775,647, forward strandXAF1FBXO39: 6,776,210–6,797,101, forward strandFBXO39TEKT1: 6,789,133–6,831,761, reverse strandTEKT1ALOX12: 6,996,049–7,010,754, forward strandALOX12RNASEK: 7,012,412–7,014,535, forward strandRNASEKRNASEK-C17orf49: 7,012,635–7,017,520, forward strandRNASEK-C17orf49BACC1: 7,014,480–7,017,544, forward strandBACC1BCL6B: 7,023,050–7,030,290, forward strandSLC16A13: 7,035,981–7,041,031, forward strandSLC16A11: 7,041,605–7,044,092, reverse strandCLEC10A: 7,074,537–7,081,166, reverse strandCLEC10AASGR2: 7,100,166–7,116,603, reverse strandASGR2ASGR1: 7,172,427–7,179,666, reverse strandASGR1DLG4: 7,187,187–7,219,836, reverse strandDLG4Diagram of SLC13A5: 12 exons on the reverse strand of chromosome 17Exon 11: 6 known disease-causing sitesExon 10: 4 known disease-causing sitesExon 9: 3 known disease-causing sitesExon 8: 5 known disease-causing sitesExon 7: 3 known disease-causing sitesExon 6: 3 known disease-causing sitesExon 5: 3 known disease-causing sitesExon 4: 4 known disease-causing sitesExon 3: 2 known disease-causing sitesExon 2: 1 known disease-causing siteExon 1: 2 known disease-causing sitesExon 12: 6,684,719–6,686,338, 1,620 basesExon 11: 6,687,529–6,687,666, 138 basesExon 10: 6,690,779–6,690,940, 162 basesExon 9: 6,693,044–6,693,162, 119 basesExon 8: 6,694,097–6,694,197, 101 basesExon 7: 6,695,726–6,695,941, 216 basesExon 6: 6,701,004–6,701,126, 123 basesExon 5: 6,702,970–6,703,138, 169 basesExon 4: 6,703,878–6,704,056, 179 basesExon 3: 6,706,642–6,706,778, 137 basesExon 2: 6,707,028–6,707,156, 129 basesExon 1: 6,713,232–6,713,369, 138 bases1210864215′3′

    Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

    Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

    Nearby genes from Ensembl release 116, on GRCh38.

    Exons make up 3.2 kb of the gene's 28.7 kb; 1,707 of those bases code for the protein.

    How a genome test reads SLC13A5

    49

    positions in SLC13A5 where ClinVar classes a change as pathogenic or likely pathogenic

    None of them falls in a region short reads find hard.

    A whole genome covers all 28.7 kb of SLC13A5, introns included, not only the 3.2 kb of exons.

    Where this comes from

    • HGNC: the gene's symbol, name, other symbols and location.
    • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
    • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
    • The ACMG secondary findings list, SF v3.2.
    • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
    • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
    • Data release 2026.10.16-c6eea6bf.

    Cite this page

    APA

    Dante Labs. (n.d.). SLC13A5 gene: solute carrier family 13 member 5. Retrieved 16 October 2026, from https://dantelabs.com/genes/slc13a5

    Vancouver

    Dante Labs. SLC13A5 gene: solute carrier family 13 member 5 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/slc13a5

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