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Trait
Low albumin
Clinical name: Hypoalbuminemia
The concentration of albumin in the blood circulation is below the lower limit of normal.
Summary
- Also called
- Low blood albumin, Decreased albumin concentration, Decreased albumin level, Decreased albumin level in blood, Decreased circulating abumin concentration, Hypoalbuminaemia, Reduced albumin concentration, Reduced albumin level, Reduced albumin level in blood
- Body system
- Laboratory abnormality
Low albuminHP:0003073
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Read the genes linked to Low albumin, and the rest of your genome, with one test.
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Get my Genome Test131 genes linked to Low albumin
Changes in these genes cause rare conditions in which Low albumin is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ACSL5acyl-CoA synthetase long chain family member 5 | Always | In 1 condition |
| AHCYadenosylhomocysteinase | Always | In 2 conditions |
| ALBalbumin | Always | In 2 conditions |
| ALG8ALG8 alpha-1,3-glucosyltransferase | Always | In 1 condition |
| ALG9ALG9 alpha-1,2-mannosyltransferase | Always | In 1 condition |
| ARHGDIARho GDP dissociation inhibitor alpha | Always | In 2 conditions |
| ATP7BATPase copper transporting beta | Always | In 1 condition |
| B2Mbeta-2-microglobulin | Always | In 1 condition |
| DCLRE1CDNA cross-link repair 1C | Always | In 1 condition |
| DHCR77-dehydrocholesterol reductase | Always | In 1 condition |
| DSG1desmoglein 1 | Always | In 1 condition |
| ERCC4ERCC excision repair 4, endonuclease catalytic subunit | Always | In 1 condition |
| FARSAphenylalanyl-tRNA synthetase subunit alpha | Always | In 1 condition |
| FARSBphenylalanyl-tRNA synthetase subunit beta | Always | In 1 condition |
| IARS1isoleucyl-tRNA synthetase 1 | Always | In 1 condition |
| IRF8interferon regulatory factor 8 | Always | In 1 condition |
| LARS2leucyl-tRNA synthetase 2, mitochondrial | Always | In 1 condition |
| MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2 | Always | In 2 conditions |
| MICOS13mitochondrial contact site and cristae organizing system subunit 13 | Always | In 1 condition |
| MYO1Emyosin IE | Always | In 2 conditions |
| NPHS1NPHS1 adhesion molecule, nephrin | Always | In 2 conditions |
| PDSS2decaprenyl diphosphate synthase subunit 2 | Always | In 1 condition |
| PET100PET100 cytochrome c oxidase chaperone | Always | In 1 condition |
| PLD4phospholipase D family member 4 | Always | In 1 condition |
| PLVAPplasmalemma vesicle associated protein | Always | In 1 condition |
| POLG2DNA polymerase gamma 2, accessory subunit | Always | In 1 condition |
| PSKH1protein serine kinase H1 | Always | In 1 condition |
| PTCRApre T cell antigen receptor alpha | Always | In 1 condition |
| PTPROprotein tyrosine phosphatase receptor type O | Always | In 2 conditions |
| RAG1recombination activating 1 | Always | In 1 condition |
| RAG2recombination activating 2 | Always | In 1 condition |
| RNF31ring finger protein 31 | Always | In 1 condition |
| SCARB2scavenger receptor class B member 2 | Always | In 1 condition |
| SH2D1ASH2 domain containing 1A | Always | In 1 condition |
| TRMUtRNA mitochondrial 2-thiouridylase | Always | In 1 condition |
| VPS33AVPS33A core subunit of CORVET and HOPS complexes | Always | In 2 conditions |
| XIAPX-linked inhibitor of apoptosis | Always | In 1 condition |
| CD55CD55 molecule (Cromer blood group) | Very often (80–99%) | In 1 condition |
| FN1fibronectin 1 | Very often (80–99%) | In 1 condition |
| IFT56intraflagellar transport 56 | Very often (80–99%) | In 1 condition |
Show 91 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| MPImannose phosphate isomerase | Very often (80–99%) | In 2 conditions |
| PRF1perforin 1 | Very often (80–99%) | In 2 conditions |
| SLC25A13solute carrier family 25 member 13 | Very often (80–99%) | In 2 conditions |
| STX11syntaxin 11 | Very often (80–99%) | In 1 condition |
| STXBP2syntaxin binding protein 2 | Very often (80–99%) | In 1 condition |
| UNC13Dunc-13 homolog D | Very often (80–99%) | In 1 condition |
| ALG1ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase | Often (30–79%) | In 1 condition |
| AP1B1adaptor related protein complex 1 subunit beta 1 | Often (30–79%) | In 1 condition |
| BMPR1Abone morphogenetic protein receptor type 1A | Often (30–79%) | In 2 conditions |
| COL7A1collagen type VII alpha 1 chain | Often (30–79%) | In 1 condition |
| EIF2AK3eukaryotic translation initiation factor 2 alpha kinase 3 | Often (30–79%) | In 1 condition |
| MPV17mitochondrial inner membrane protein MPV17 | Often (30–79%) | In 1 condition |
| MTTPmicrosomal triglyceride transfer protein | Often (30–79%) | In 1 condition |
| MYO5Bmyosin VB | Often (30–79%) | In 1 condition |
| NLRC4NLR family CARD domain containing 4 | Often (30–79%) | In 1 condition |
| PNKPpolynucleotide kinase 3'-phosphatase | Often (30–79%) | In 1 condition |
| PTENphosphatase and tensin homolog | Often (30–79%) | In 1 condition |
| SLCO2A1solute carrier organic anion transporter family member 2A1 | Often (30–79%) | In 1 condition |
| SYKspleen associated tyrosine kinase | Often (30–79%) | In 1 condition |
| TDP1tyrosyl-DNA phosphodiesterase 1 | Often (30–79%) | In 2 conditions |
| TFAMtranscription factor A, mitochondrial | Often (30–79%) | In 1 condition |
| ACTN4actinin alpha 4 | Sometimes (5–29%) | In 2 conditions |
| ALG12ALG12 alpha-1,6-mannosyltransferase | Sometimes (5–29%) | In 1 condition |
| ALG6ALG6 alpha-1,3-glucosyltransferase | Sometimes (5–29%) | In 1 condition |
| ANKFY1ankyrin repeat and FYVE domain containing 1 | Sometimes (5–29%) | In 1 condition |
| ANLNanillin, actin binding protein | Sometimes (5–29%) | In 1 condition |
| AP1S3adaptor related protein complex 1 subunit sigma 3 | Sometimes (5–29%) | In 1 condition |
| APOL1apolipoprotein L1 | Sometimes (5–29%) | In 1 condition |
| ARHGAP24Rho GTPase activating protein 24 | Sometimes (5–29%) | In 1 condition |
| AVILadvillin | Sometimes (5–29%) | In 1 condition |
| CD2APCD2 associated protein | Sometimes (5–29%) | In 1 condition |
| COL4A3collagen type IV alpha 3 chain | Sometimes (5–29%) | In 1 condition |
| COQ8Bcoenzyme Q8B | Sometimes (5–29%) | In 2 conditions |
| CRB2crumbs cell polarity complex component 2 | Sometimes (5–29%) | In 1 condition |
| DAAM2dishevelled associated activator of morphogenesis 2 | Sometimes (5–29%) | In 1 condition |
| EMP2epithelial membrane protein 2 | Sometimes (5–29%) | In 1 condition |
| FOXP3forkhead box P3 | Sometimes (5–29%) | In 1 condition |
| GAPVD1GTPase activating protein and VPS9 domains 1 | Sometimes (5–29%) | In 1 condition |
| GFM1G elongation factor mitochondrial 1 | Sometimes (5–29%) | In 1 condition |
| GPR35G protein-coupled receptor 35 | Sometimes (5–29%) | In 1 condition |
| IL12Ainterleukin 12A | Sometimes (5–29%) | In 1 condition |
| IL12RB1interleukin 12 receptor subunit beta 1 | Sometimes (5–29%) | In 1 condition |
| IL36RNinterleukin 36 receptor antagonist | Sometimes (5–29%) | In 1 condition |
| INF2inverted formin 2 | Sometimes (5–29%) | In 1 condition |
| IRF5interferon regulatory factor 5 | Sometimes (5–29%) | In 1 condition |
| KANK2KN motif and ankyrin repeat domains 2 | Sometimes (5–29%) | In 1 condition |
| KRT14keratin 14 | Sometimes (5–29%) | In 1 condition |
| KRT5keratin 5 | Sometimes (5–29%) | In 1 condition |
| LAMA5laminin subunit alpha 5 | Sometimes (5–29%) | In 1 condition |
| MAP2K1mitogen-activated protein kinase kinase 1 | Sometimes (5–29%) | In 1 condition |
| MMEL1membrane metalloendopeptidase like 1 | Sometimes (5–29%) | In 1 condition |
| MST1macrophage stimulating 1 | Sometimes (5–29%) | In 1 condition |
| NPHS2NPHS2 stomatin family member, podocin | Sometimes (5–29%) | In 2 conditions |
| NRASNRAS proto-oncogene, GTPase | Sometimes (5–29%) | In 1 condition |
| NUP107nucleoporin 107 | Sometimes (5–29%) | In 2 conditions |
| NUP133nucleoporin 133 | Sometimes (5–29%) | In 2 conditions |
| NUP160nucleoporin 160 | Sometimes (5–29%) | In 1 condition |
| NUP205nucleoporin 205 | Sometimes (5–29%) | In 1 condition |
| NUP37nucleoporin 37 | Sometimes (5–29%) | In 1 condition |
| NUP85nucleoporin 85 | Sometimes (5–29%) | In 1 condition |
| NUP93nucleoporin 93 | Sometimes (5–29%) | In 1 condition |
| PAX2paired box 2 | Sometimes (5–29%) | In 1 condition |
| PIK3R5phosphoinositide-3-kinase regulatory subunit 5 | Sometimes (5–29%) | In 1 condition |
| PLCE1phospholipase C epsilon 1 | Sometimes (5–29%) | In 2 conditions |
| PMM2phosphomannomutase 2 | Sometimes (5–29%) | In 2 conditions |
| POU2AF1POU class 2 homeobox associating factor 1 | Sometimes (5–29%) | In 1 condition |
| RNU7-1RNA, U7 small nuclear 1 | Sometimes (5–29%) | In 1 condition |
| SEMA4Dsemaphorin 4D | Sometimes (5–29%) | In 1 condition |
| SETXsenataxin | Sometimes (5–29%) | In 1 condition |
| SPIBSpi-B transcription factor | Sometimes (5–29%) | In 1 condition |
| TBC1D8BTBC1 domain family member 8B | Sometimes (5–29%) | In 1 condition |
| TCF4transcription factor 4 | Sometimes (5–29%) | In 1 condition |
| TKFCtriokinase and FMN cyclase | Sometimes (5–29%) | In 1 condition |
| TNFSF15TNF superfamily member 15 | Sometimes (5–29%) | In 1 condition |
| TNPO3transportin 3 | Sometimes (5–29%) | In 1 condition |
| TRPC6transient receptor potential cation channel subfamily C member 6 | Sometimes (5–29%) | In 1 condition |
| WT1WT1 transcription factor | Sometimes (5–29%) | In 1 condition |
| WDR4WDR4 tRNA N7-guanosine methyltransferase non-catalytic subunit | Rarely (1–4%) | In 1 condition |
| APTXaprataxin | Not recorded | In 1 condition |
| CCBE1collagen and calcium binding EGF domains 1 | Not recorded | In 1 condition |
| DGAT1diacylglycerol O-acyltransferase 1 | Not recorded | In 1 condition |
| DGKEdiacylglycerol kinase epsilon | Not recorded | In 1 condition |
| DGUOKdeoxyguanosine kinase | Not recorded | In 1 condition |
| IFNGR1interferon gamma receptor 1 | Not recorded | In 1 condition |
| ITGA3integrin subunit alpha 3 | Not recorded | In 1 condition |
| OSGEPO-sialoglycoprotein endopeptidase | Not recorded | In 1 condition |
| SAR1Bsecretion associated Ras related GTPase 1B | Not recorded | In 1 condition |
| SGPL1sphingosine-1-phosphate lyase 1 | Not recorded | In 1 condition |
| SKIC3SKI3 subunit of superkiller complex | Not recorded | In 1 condition |
| SMAD4SMAD family member 4 | Not recorded | In 1 condition |
| WDR73WD repeat domain 73 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Who We HelpOur ScienceProductsOutcomes
Log InAskGet Startedfrom $449
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks