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Gene

AP1S3

adaptor related protein complex 1 subunit sigma 3

Summary

Cytogenetic location
2q36.1
Coordinates
Chromosome 2: 223,755,326–223,837,582 (GRCh38)
Exons
5 exons across 82.3 kb
Protein
154 amino acids
Also known as
sigma1C
MANE Select transcript
ENST00000396654.7NM_001039569.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads AP1S3 yet. The test sequences your whole genome, so your data includes it all the same.

How AP1S3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 2, with a bracket where AP1S3 sits. AP1S3 and 5 genes near it on chromosome 2, from 223,296,454 to 224,296,453.Chromosome 22q36.1p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.3223.4 Mb223.6 Mb223.8 Mb224 Mb224.2 MbSCG2: 223,596,092–223,602,773, reverse strandSCG2AP1S3: 223,755,326–223,837,582, reverse strandAP1S3: 223,757,258–223,945,299, reverse strandWDFY1: 223,855,716–223,945,357, reverse strandWDFY1MRPL44: 223,957,386–223,969,078, forward strandMRPL44SERPINE2: 223,975,045–224,039,688, reverse strandSERPINE2Diagram of AP1S3: 5 exons on the reverse strand of chromosome 2Exon 5: 223,755,326–223,758,750, 3,425 basesExon 4: 223,765,213–223,765,350, 138 basesExon 3: 223,775,901–223,776,009, 109 basesExon 2: 223,777,691–223,777,869, 179 basesExon 1: 223,837,448–223,837,582, 135 bases543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4 kb of the gene's 82.3 kb; 465 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). AP1S3 gene: adaptor related protein complex 1 subunit sigma 3. Retrieved 16 October 2026, from https://dantelabs.com/genes/ap1s3

Vancouver

Dante Labs. AP1S3 gene: adaptor related protein complex 1 subunit sigma 3 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/ap1s3

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