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Gene

NUP93

nucleoporin 93

Summary

Cytogenetic location
16q13
Coordinates
Chromosome 16: 56,730,129–56,850,286 (GRCh38)
Exons
22 exons across 120.2 kb
Protein
819 amino acids
Also known as
KIAA0095
MANE Select transcript
ENST00000308159.10NM_014669.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

  • Nephrotic Syndrome

    • Nephrosis

      Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.

      • ClinGen rates the link definitive
      • 4 GenCC submitters rate it definitive or strong

How NUP93 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 16, with a bracket where NUP93 sits. NUP93 and 26 genes near it on chromosome 16, from 56,290,208 to 57,290,207.Chromosome 1616q13p13.3p13.2p13.13p13.12p13.11p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q13q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.356.4 Mb56.6 Mb56.8 Mb57 Mb57.2 MbGNAO1: 56,189,660–56,357,444, forward strandGNAO1AMFR: 56,361,449–56,425,598, reverse strandAMFRNUDT21: 56,428,473–56,452,199, reverse strandNUDT21: 56,430,556–56,501,497, reverse strandOGFOD1: 56,451,508–56,479,122, forward strandOGFOD1BBS2: 56,465,640–56,582,667, reverse strandBBS2MT4: 56,565,073–56,569,108, forward strandMT4MT3: 56,589,074–56,591,093, forward strandMT3MT2A: 56,608,130–56,609,503, forward strandMT2AMT1E: 56,625,475–56,627,112, forward strandMT1EMT1M: 56,632,485–56,633,986, forward strandMT1A: 56,638,202–56,640,087, forward strandMT1B: 56,651,885–56,653,204, forward strandMT1F: 56,657,640–56,660,698, forward strandMT1FMT1G: 56,666,730–56,668,072, reverse strandMT1GMT1H: 56,669,660–56,671,135, forward strandMT1HMT1X: 56,682,058–56,686,110, forward strandMT1XNUP93: 56,730,129–56,850,286, forward strandNUP93SLC12A3: 56,865,203–56,915,850, forward strandSLC12A3HERPUD1: 56,930,815–56,946,491, forward strandHERPUD1CETP: 56,961,922–56,983,845, forward strandCETPNLRC5: 56,989,485–57,084,238, forward strandNLRC5CPNE2: 57,092,517–57,148,369, forward strandCPNE2PSME3IP1: 57,152,466–57,186,175, reverse strandPSME3IP1RSPRY1: 57,186,137–57,242,505, forward strandRSPRY1ARL2BP: 57,245,098–57,259,830, forward strandARL2BPPLLP: 57,248,547–57,284,683, reverse strandPLLPDiagram of NUP93: 22 exons on the forward strand of chromosome 16Exon 5: 1 known disease-causing siteExon 8: 1 known disease-causing siteExon 13: 1 known disease-causing siteExon 15: 2 known disease-causing sitesExon 16: 1 known disease-causing siteExon 17: 1 known disease-causing siteExon 1: 56,730,129–56,730,211, 83 basesExon 2: 56,748,234–56,748,426, 193 basesExon 3: 56,758,538–56,758,655, 118 basesExon 4: 56,798,476–56,798,538, 63 basesExon 5: 56,805,504–56,805,632, 129 basesExon 6: 56,818,664–56,818,738, 75 basesExon 7: 56,821,504–56,821,593, 90 basesExon 8: 56,823,707–56,823,846, 140 basesExon 9: 56,828,977–56,829,109, 133 basesExon 10: 56,830,528–56,830,685, 158 basesExon 11: 56,831,842–56,832,007, 166 basesExon 12: 56,832,295–56,832,388, 94 basesExon 13: 56,833,215–56,833,406, 192 basesExon 14: 56,834,128–56,834,254, 127 basesExon 15: 56,834,370–56,834,442, 73 basesExon 16: 56,834,734–56,834,778, 45 basesExon 17: 56,836,601–56,836,717, 117 basesExon 18: 56,837,608–56,837,726, 119 basesExon 19: 56,838,952–56,839,069, 118 basesExon 20: 56,839,521–56,839,604, 84 basesExon 21: 56,841,705–56,841,833, 129 basesExon 22: 56,844,499–56,850,286, 5,788 bases15101520225′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 8.2 kb of the gene's 120.2 kb; 2,460 of those bases code for the protein.

How a genome test reads NUP93

9

positions in NUP93 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 120.2 kb of NUP93, introns included, not only the 8.2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). NUP93 gene: nucleoporin 93. Retrieved 16 October 2026, from https://dantelabs.com/genes/nup93

Vancouver

Dante Labs. NUP93 gene: nucleoporin 93 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/nup93

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