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Trait
Decreased arm strength
Clinical name: Upper limb muscle weakness
Weakness of the muscles of the arms.
Summary
- Also called
- Weak arm
Decreased arm strengthHP:0003484
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Read the genes linked to Decreased arm strength, and the rest of your genome, with one test.
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Get my Genome Test93 genes linked to Decreased arm strength
Changes in these genes cause rare conditions in which Decreased arm strength is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ARHGAP19Rho GTPase activating protein 19 | Always | In 1 condition |
| CFL2cofilin 2 | Always | In 1 condition |
| CHRNA1cholinergic receptor nicotinic alpha 1 subunit | Always | In 1 condition |
| DSTdystonin | Always | In 1 condition |
| IGHMBP2immunoglobulin mu DNA binding protein 2 | Always | In 1 condition |
| KLC4kinesin light chain 4 | Always | In 1 condition |
| LMNAlamin A/C | Always | In 2 conditions |
| NDC1NDC1 transmembrane nucleoporin | Always | In 1 condition |
| PDXKpyridoxal kinase | Always | In 1 condition |
| SBF1SET binding factor 1 | Always | In 1 condition |
| SPTAN1spectrin alpha, non-erythrocytic 1 | Always | In 2 conditions |
| NEFLneurofilament light chain | Very often (80–99%) | In 1 condition |
| SEPTIN9septin 9 | Very often (80–99%) | In 1 condition |
| TFGtrafficking from ER to golgi regulator | Very often (80–99%) | In 1 condition |
| ANGangiogenin | Often (30–79%) | In 1 condition |
| ANXA11annexin A11 | Often (30–79%) | In 1 condition |
| ATXN2ataxin 2 | Often (30–79%) | In 1 condition |
| BSCL2BSCL2 lipid droplet biogenesis associated, seipin | Often (30–79%) | In 1 condition |
| CCNFcyclin F | Often (30–79%) | In 1 condition |
| CFAP410cilia and flagella associated protein 410 | Often (30–79%) | In 1 condition |
| CHCHD10coiled-coil-helix-coiled-coil-helix domain containing 10 | Often (30–79%) | In 1 condition |
| CHMP2Bcharged multivesicular body protein 2B | Often (30–79%) | In 1 condition |
| COL25A1collagen type XXV alpha 1 chain | Often (30–79%) | In 1 condition |
| DAOD-amino acid oxidase | Often (30–79%) | In 1 condition |
| DCTN1dynactin subunit 1 | Often (30–79%) | In 1 condition |
| ERBB4erb-b2 receptor tyrosine kinase 4 | Often (30–79%) | In 1 condition |
| ERGIC1endoplasmic reticulum-golgi intermediate compartment 1 | Often (30–79%) | In 1 condition |
| FIG4FIG4 phosphoinositide 5-phosphatase | Often (30–79%) | In 1 condition |
| FUSFUS RNA binding protein | Often (30–79%) | In 1 condition |
| GARS1glycyl-tRNA synthetase 1 | Often (30–79%) | In 3 conditions |
| GDAP1ganglioside induced differentiation associated protein 1 | Often (30–79%) | In 1 condition |
| GLE1GLE1 RNA export mediator | Often (30–79%) | In 1 condition |
| GLT8D1glycosyltransferase 8 domain containing 1 | Often (30–79%) | In 1 condition |
| GYG1glycogenin 1 | Often (30–79%) | In 1 condition |
| HEXBhexosaminidase subunit beta | Often (30–79%) | In 1 condition |
| HNRNPA1heterogeneous nuclear ribonucleoprotein A1 | Often (30–79%) | In 1 condition |
| INPP4Ainositol polyphosphate-4-phosphatase type I A | Often (30–79%) | In 1 condition |
| KIF5Akinesin family member 5A | Often (30–79%) | In 1 condition |
| LRP12LDL receptor related protein 12 | Often (30–79%) | In 2 conditions |
| MATR3matrin 3 | Often (30–79%) | In 1 condition |
Show 53 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| MORC2MORC family CW-type zinc finger 2 | Often (30–79%) | In 1 condition |
| MTRFRmitochondrial translation release factor in rescue | Often (30–79%) | In 2 conditions |
| NEFHneurofilament heavy chain | Often (30–79%) | In 2 conditions |
| NEK1NIMA related kinase 1 | Often (30–79%) | In 1 condition |
| OPTNoptineurin | Often (30–79%) | In 1 condition |
| PFN1profilin 1 | Often (30–79%) | In 1 condition |
| PIEZO2piezo type mechanosensitive ion channel component 2 | Often (30–79%) | In 1 condition |
| PRPHperipherin | Often (30–79%) | In 1 condition |
| REEP1receptor accessory protein 1 | Often (30–79%) | In 1 condition |
| SCYL2SCY1 like pseudokinase 2 | Often (30–79%) | In 1 condition |
| SGCGsarcoglycan gamma | Often (30–79%) | In 1 condition |
| SOD1superoxide dismutase 1 | Often (30–79%) | In 1 condition |
| SPARTspartin | Often (30–79%) | In 1 condition |
| SQSTM1sequestosome 1 | Often (30–79%) | In 1 condition |
| TAF15TATA-box binding protein associated factor 15 | Often (30–79%) | In 1 condition |
| TARDBPTAR DNA binding protein | Often (30–79%) | In 1 condition |
| TBK1TANK binding kinase 1 | Often (30–79%) | In 1 condition |
| TREM2triggering receptor expressed on myeloid cells 2 | Often (30–79%) | In 1 condition |
| UBQLN2ubiquilin 2 | Often (30–79%) | In 1 condition |
| UNC13Aunc-13 homolog A | Often (30–79%) | In 1 condition |
| VAPBVAMP associated protein B and C | Often (30–79%) | In 2 conditions |
| VCPvalosin containing protein | Often (30–79%) | In 1 condition |
| ZFYVE26zinc finger FYVE-type containing 26 | Often (30–79%) | In 1 condition |
| ADARadenosine deaminase RNA specific | Sometimes (5–29%) | In 1 condition |
| AKT1AKT serine/threonine kinase 1 | Sometimes (5–29%) | In 1 condition |
| B4GALNT1beta-1,4-N-acetyl-galactosaminyltransferase 1 | Sometimes (5–29%) | In 1 condition |
| BAP1BRCA1 associated deubiquitinase 1 | Sometimes (5–29%) | In 1 condition |
| CCND1cyclin D1 | Sometimes (5–29%) | In 1 condition |
| CYP7B1cytochrome P450 family 7 subfamily B member 1 | Sometimes (5–29%) | In 2 conditions |
| GALCgalactosylceramidase | Sometimes (5–29%) | In 2 conditions |
| MT-ATP6mitochondrially encoded ATP synthase membrane subunit 6 | Sometimes (5–29%) | In 1 condition |
| NF2NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor | Sometimes (5–29%) | In 1 condition |
| NUP54nucleoporin 54 | Sometimes (5–29%) | In 1 condition |
| NUP62nucleoporin 62 | Sometimes (5–29%) | In 1 condition |
| PDGFBplatelet derived growth factor subunit B | Sometimes (5–29%) | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Sometimes (5–29%) | In 1 condition |
| POU3F4POU class 3 homeobox 4 | Sometimes (5–29%) | In 1 condition |
| RAB3ARAB3A, member RAS oncogene family | Sometimes (5–29%) | In 1 condition |
| SMARCB1SWI/SNF related BAF chromatin remodeling complex subunit B1 | Sometimes (5–29%) | In 1 condition |
| SMARCE1SWI/SNF related BAF chromatin remodeling complex subunit E1 | Sometimes (5–29%) | In 1 condition |
| SMOsmoothened, frizzled class receptor | Sometimes (5–29%) | In 1 condition |
| SPG7SPG7 matrix AAA peptidase subunit, paraplegin | Sometimes (5–29%) | In 2 conditions |
| SUFUSUFU negative regulator of hedgehog signaling | Sometimes (5–29%) | In 1 condition |
| TERTtelomerase reverse transcriptase | Sometimes (5–29%) | In 1 condition |
| TRAF7TNF receptor associated factor 7 | Sometimes (5–29%) | In 1 condition |
| TUBA4Atubulin alpha 4a | Sometimes (5–29%) | In 1 condition |
| VHLvon Hippel-Lindau tumor suppressor | Sometimes (5–29%) | In 1 condition |
| DNMT3BDNA methyltransferase 3 beta | Not recorded | In 1 condition |
| EGR2early growth response 2 | Not recorded | In 2 conditions |
| FGD4FYVE, RhoGEF and PH domain containing 4 | Not recorded | In 1 condition |
| MPZmyelin protein zero | Not recorded | In 2 conditions |
| SH3TC2SH3 domain and tetratricopeptide repeats 2 | Not recorded | In 1 condition |
| YARS1tyrosyl-tRNA synthetase 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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Log InAskGet Startedfrom $449
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