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Trait
Posterior subcapsular cataract
A type of cataract affecting the posterior pole of lens immediately adjacent to ('beneath') the Lens capsule.
Summary
- Also called
- Posterior subcapsular opacities of the lens
- Body system
- Abnormality of the eye
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library(jsonlite)
url <- "https://dantelabs.com/traits/posterior-subcapsular-cataract.json"
page <- fromJSON(url)
page$trait$namePosterior subcapsular cataractHP:0007787
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Get my Genome Test49 condition reports read genes linked to this trait
Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.
- Retinitis PigmentosaReads 74 of these genesARL3RBP3TULP1ZNF408ABCA4AGBL5About this report →
- Leber Congenital Amaurosis & RPE65-Related RetinopathyReads 13 of these genesTULP1CRB1CRXIMPDH1LRATPRPH2About this report →
- Bardet-Biedl and Alström SyndromesReads 8 of these genesARL6BBS1BBS2BBS5CFAP418IFT172About this report →
- Hereditary Macular DystrophiesReads 5 of these genesBEST1PRPH2RLBP1ROM1RP1L1About this report →
Show 45 more reports
- Congenital Stationary Night BlindnessReads 6 of these genesPDE6BPRPH2RHORLBP1SAGCABP4About this report →
- VitreoretinopathyReads 6 of these genesZNF408BEST1NR2E3NRLXYLT2KCNJ13About this report →
- RDH5-Related Retinopathy (Fundus Albipunctatus)Reads 2 of these genesPRPH2RLBP1About this report →
- Stargardt DiseaseReads 2 of these genesABCA4PROM1About this report →
- ChoroideremiaReads 1 of these genesCHMAbout this report →
- Gyrate Atrophy of the Choroid and RetinaReads 1 of these genesOATAbout this report →
- IFT140-Related CiliopathyReads 1 of these genesIFT140About this report →
- IMPG1-Related Dominant RetinopathyReads 1 of these genesIMPG1About this report →
- IMPG1-Related RetinopathyReads 1 of these genesIMPG1About this report →
- Microcornea-Myopic Chorioretinal AtrophyReads 1 of these genesADAMTS18About this report →
- OFD1-Related CiliopathyReads 1 of these genesOFD1About this report →
- PROM1-Related Recessive RetinopathyReads 1 of these genesPROM1About this report →
- RDH12-Related Early-Onset Retinal DystrophyReads 1 of these genesRDH12About this report →
- Joubert Syndrome And Related DisordersReads 5 of these genesARL3AHI1CC2D2AOFD1TMEM216About this report →
- Myotonic DystrophyReads 1 of these genesCNBPAbout this report →
- Usher SyndromeReads 2 of these genesCLRN1USH2AAbout this report →
- Mucopolysaccharidosis Type III (Sanfilippo Syndrome)Reads 1 of these genesHGSNATAbout this report →
- NeurofibromatosisReads 1 of these genesNF2About this report →
- Hereditary Congenital & Juvenile CataractReads 2 of these genesUNC45BCHMP4BAbout this report →
- Autosomal Recessive Cerebellar Ataxias (incl. CANVAS and AVED)Reads 3 of these genesAHI1CC2D2ATMEM216About this report →
- Autoimmune Lymphoproliferative Syndrome (ALPS)Reads 1 of these genesFASAbout this report →
- Ellis-van Creveld Syndrome and Cranioectodermal DysplasiaReads 1 of these genesIFT43About this report →
- Anterior Segment Dysgenesis, Axenfeld-Rieger Syndrome & AniridiaReads 1 of these genesFOXE3About this report →
- Polycystic Kidney DiseaseReads 1 of these genesIFT140About this report →
- Aortic AneurysmReads 1 of these genesFOXE3About this report →
- Hereditary Optic NeuropathyReads 1 of these genesOPA3About this report →
- Myofibrillar MyopathiesReads 1 of these genesUNC45BAbout this report →
- Neuronal Ceroid LipofuscinosisReads 1 of these genesCLN3About this report →
- Lysosomal Storage DiseaseReads 2 of these genesCLN3HGSNATAbout this report →
- Inherited Neurodegenerative DisordersReads 5 of these genesAHI1CC2D2ACLN3TMEM216OPA3About this report →
- Autoimmune DiseaseReads 1 of these genesFASAbout this report →
- Hereditary Sensory and Autonomic Neuropathies (incl. Familial Dysautonomia)Reads 1 of these genesKLHL7About this report →
- Syndromic Complex Neurodevelopmental DisorderReads 1 of these genesRNU4-2About this report →
- Syndromic CraniosynostosisReads 1 of these genesIFT43About this report →
- Congenital Disorders of GlycosylationReads 2 of these genesDHDDSPOMGNT1About this report →
- Non-Acquired Combined Pituitary Hormone DeficiencyReads 1 of these genesOTX2About this report →
- Microphthalmia, Anophthalmia & ColobomaReads 1 of these genesOTX2About this report →
- Congenital Muscular DystrophiesReads 1 of these genesPOMGNT1About this report →
- Nephrotic SyndromeReads 1 of these genesCOQ8BAbout this report →
- Limb-Girdle Muscular DystrophyReads 1 of these genesPOMGNT1About this report →
- Osteogenesis ImperfectaReads 1 of these genesXYLT2About this report →
- Hypogonadotropic HypogonadismReads 1 of these genesOTX2About this report →
- Rare Hereditary Peripheral NeuropathiesReads 2 of these genesKLHL7OATAbout this report →
- Other Inborn Errors of ImmunityReads 1 of these genesFASAbout this report →
- Intellectual DisabilityReads 1 of these genesSCAPERAbout this report →
Read the genes linked to Posterior subcapsular cataract, and the rest of your genome, with one test.
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Get my Genome Test126 genes linked to Posterior subcapsular cataract
Changes in these genes cause rare conditions in which Posterior subcapsular cataract is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ARL3ARF like GTPase 3 | Always | In 2 conditions |
| CNBPCCHC-type zinc finger nucleic acid binding protein | Always | In 2 conditions |
| HYAL2hyaluronidase 2 | Always | In 1 condition |
| NR6A1nuclear receptor subfamily 6 group A member 1 | Always | In 1 condition |
| RBP3retinol binding protein 3 | Always | In 2 conditions |
| TULP1TUB like protein 1 | Always | In 3 conditions |
| UBAP1Lubiquitin associated protein 1 like | Always | In 1 condition |
| UNC45Bunc-45 myosin chaperone B | Always | In 1 condition |
| ZNF408zinc finger protein 408 | Always | In 2 conditions |
| ABCA4ATP binding cassette subfamily A member 4 | Often (30–79%) | In 1 condition |
| AGBL5AGBL carboxypeptidase 5 | Often (30–79%) | In 1 condition |
| AHI1Abelson helper integration site 1 | Often (30–79%) | In 1 condition |
| AHRaryl hydrocarbon receptor | Often (30–79%) | In 1 condition |
| ARHGEF18Rho/Rac guanine nucleotide exchange factor 18 | Often (30–79%) | In 1 condition |
| ARL2BPARF like GTPase 2 binding protein | Often (30–79%) | In 2 conditions |
| ARL6ARF like GTPase 6 | Often (30–79%) | In 1 condition |
| BBS1Bardet-Biedl syndrome 1 | Often (30–79%) | In 1 condition |
| BBS2Bardet-Biedl syndrome 2 | Often (30–79%) | In 1 condition |
| BBS5Bardet-Biedl syndrome 5 | Often (30–79%) | In 1 condition |
| BEST1bestrophin 1 | Often (30–79%) | In 1 condition |
| CA4carbonic anhydrase 4 | Often (30–79%) | In 1 condition |
| CC2D2Acoiled-coil and C2 domain containing 2A | Often (30–79%) | In 1 condition |
| CDHR1cadherin related family member 1 | Often (30–79%) | In 1 condition |
| CERKLCERK like autophagy regulator | Often (30–79%) | In 1 condition |
| CFAP20cilia and flagella associated protein 20 | Often (30–79%) | In 1 condition |
| CFAP410cilia and flagella associated protein 410 | Often (30–79%) | In 1 condition |
| CFAP418cilia and flagella associated protein 418 | Often (30–79%) | In 1 condition |
| CLN3CLN3 lysosomal/endosomal transmembrane protein, battenin | Often (30–79%) | In 1 condition |
| CLRN1clarin 1 | Often (30–79%) | In 1 condition |
| CNGA1cyclic nucleotide gated channel subunit alpha 1 | Often (30–79%) | In 1 condition |
| CNGB1cyclic nucleotide gated channel subunit beta 1 | Often (30–79%) | In 1 condition |
| COQ8Bcoenzyme Q8B | Often (30–79%) | In 1 condition |
| CRB1crumbs cell polarity complex component 1 | Often (30–79%) | In 1 condition |
| CRXcone-rod homeobox | Often (30–79%) | In 1 condition |
| DHDDSdehydrodolichyl diphosphate synthase subunit | Often (30–79%) | In 1 condition |
| DHX38DEAH-box helicase 38 | Often (30–79%) | In 1 condition |
| EYSEGF-like photoreceptor maintenance factor | Often (30–79%) | In 2 conditions |
| FAM161AFAM161 centrosomal protein A | Often (30–79%) | In 1 condition |
| FASFas cell surface death receptor | Often (30–79%) | In 1 condition |
| FSCN2fascin actin-bundling protein 2, retinal | Often (30–79%) | In 1 condition |
Show 86 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| FSD1Lfibronectin type III and SPRY domain containing 1 like | Often (30–79%) | In 2 conditions |
| GUCA1Bguanylate cyclase activator 1B | Often (30–79%) | In 1 condition |
| HGSNATheparan-alpha-glucosaminide N-acetyltransferase | Often (30–79%) | In 1 condition |
| HKDC1hexokinase domain containing 1 | Often (30–79%) | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Often (30–79%) | In 1 condition |
| IDH3Aisocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha | Often (30–79%) | In 1 condition |
| IDH3Bisocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta | Often (30–79%) | In 2 conditions |
| IFT140intraflagellar transport 140 | Often (30–79%) | In 1 condition |
| IFT172intraflagellar transport 172 | Often (30–79%) | In 1 condition |
| IFT43intraflagellar transport 43 | Often (30–79%) | In 1 condition |
| IFT88intraflagellar transport 88 | Often (30–79%) | In 1 condition |
| IMPDH1inosine monophosphate dehydrogenase 1 | Often (30–79%) | In 2 conditions |
| IMPG1interphotoreceptor matrix proteoglycan 1 | Often (30–79%) | In 1 condition |
| IMPG2interphotoreceptor matrix proteoglycan 2 | Often (30–79%) | In 2 conditions |
| KIAA1549KIAA1549 | Often (30–79%) | In 1 condition |
| KIZkizuna centrosomal protein | Often (30–79%) | In 1 condition |
| KLHL7kelch like family member 7 | Often (30–79%) | In 1 condition |
| LRATlecithin retinol acyltransferase | Often (30–79%) | In 2 conditions |
| MAKmale germ cell associated kinase | Often (30–79%) | In 1 condition |
| MERTKMER proto-oncogene, tyrosine kinase | Often (30–79%) | In 1 condition |
| NEK2NIMA related kinase 2 | Often (30–79%) | In 1 condition |
| NF2NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor | Often (30–79%) | In 2 conditions |
| NR2E3nuclear receptor subfamily 2 group E member 3 | Often (30–79%) | In 2 conditions |
| NRLneural retina leucine zipper | Often (30–79%) | In 1 condition |
| OFD1OFD1 centriole and centriolar satellite protein | Often (30–79%) | In 2 conditions |
| PCAREphotoreceptor cilium actin regulator | Often (30–79%) | In 1 condition |
| PDE6Aphosphodiesterase 6A | Often (30–79%) | In 2 conditions |
| PDE6Bphosphodiesterase 6B | Often (30–79%) | In 1 condition |
| PDE6Gphosphodiesterase 6G | Often (30–79%) | In 1 condition |
| POLR3GLRNA polymerase III subunit GL | Often (30–79%) | In 1 condition |
| POMGNT1protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) | Often (30–79%) | In 1 condition |
| PRCDphotoreceptor disc component | Often (30–79%) | In 1 condition |
| PROM1prominin 1 | Often (30–79%) | In 1 condition |
| PRPF3pre-mRNA processing factor 3 | Often (30–79%) | In 1 condition |
| PRPF31pre-mRNA processing factor 31 | Often (30–79%) | In 1 condition |
| PRPF4pre-mRNA splicing tri-snRNP complex factor PRPF4 | Often (30–79%) | In 1 condition |
| PRPF6pre-mRNA processing factor 6 | Often (30–79%) | In 2 conditions |
| PRPF8pre-mRNA processing factor 8 | Often (30–79%) | In 1 condition |
| PRPH2peripherin 2 | Often (30–79%) | In 2 conditions |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Often (30–79%) | In 1 condition |
| RDH12retinol dehydrogenase 12 | Often (30–79%) | In 1 condition |
| REEP6receptor accessory protein 6 | Often (30–79%) | In 2 conditions |
| RGRretinal G protein coupled receptor | Often (30–79%) | In 1 condition |
| RHOrhodopsin | Often (30–79%) | In 1 condition |
| RLBP1retinaldehyde binding protein 1 | Often (30–79%) | In 1 condition |
| RNU4-2RNA, U4 small nuclear 2 | Often (30–79%) | In 1 condition |
| RNU6-1RNA, U6 small nuclear 1 | Often (30–79%) | In 1 condition |
| RNU6-2RNA, U6 small nuclear 2 | Often (30–79%) | In 1 condition |
| RNU6-8RNA, U6 small nuclear 8 | Often (30–79%) | In 1 condition |
| RNU6-9RNA, U6 small nuclear 9 | Often (30–79%) | In 1 condition |
| ROM1retinal outer segment membrane protein 1 | Often (30–79%) | In 1 condition |
| RP1RP1 axonemal microtubule associated | Often (30–79%) | In 1 condition |
| RP1L1RP1 like 1 | Often (30–79%) | In 1 condition |
| RP2RP2 activator of ARL3 GTPase | Often (30–79%) | In 1 condition |
| RP9RP9 pre-mRNA splicing factor | Often (30–79%) | In 1 condition |
| RPE65retinoid isomerohydrolase RPE65 | Often (30–79%) | In 2 conditions |
| RPGRretinitis pigmentosa GTPase regulator | Often (30–79%) | In 1 condition |
| RPGRIP1RPGR interacting protein 1 | Often (30–79%) | In 2 conditions |
| SAGS-antigen visual arrestin | Often (30–79%) | In 1 condition |
| SAXO6stabilizer of axonemal microtubules 6 | Often (30–79%) | In 1 condition |
| SCAPERS-phase cyclin A associated protein in the ER | Often (30–79%) | In 2 conditions |
| SEMA4Asemaphorin 4A | Often (30–79%) | In 1 condition |
| SLC7A14solute carrier family 7 member 14 | Often (30–79%) | In 1 condition |
| SNRNP200small nuclear ribonucleoprotein U5 subunit 200 | Often (30–79%) | In 1 condition |
| SPATA7spermatogenesis associated 7 | Often (30–79%) | In 2 conditions |
| TMEM216transmembrane protein 216 | Often (30–79%) | In 1 condition |
| TOPORSTOP1 binding arginine/serine rich protein, E3 ubiquitin ligase | Often (30–79%) | In 1 condition |
| TTC8tetratricopeptide repeat domain 8 | Often (30–79%) | In 1 condition |
| TUBTUB bipartite transcription factor | Often (30–79%) | In 1 condition |
| USH2Ausherin | Often (30–79%) | In 1 condition |
| XYLT2xylosyltransferase 2 | Often (30–79%) | In 1 condition |
| ZNF513zinc finger protein 513 | Often (30–79%) | In 1 condition |
| ADAMTS18ADAM metallopeptidase with thrombospondin type 1 motif 18 | Sometimes (5–29%) | In 1 condition |
| ALMS1ALMS1 centrosome and basal body associated protein | Sometimes (5–29%) | In 2 conditions |
| CABP4calcium binding protein 4 | Sometimes (5–29%) | In 1 condition |
| CHMCHM Rab escort protein | Sometimes (5–29%) | In 1 condition |
| KCNJ13potassium inwardly rectifying channel subfamily J member 13 | Sometimes (5–29%) | In 1 condition |
| LCA5lebercilin LCA5 | Sometimes (5–29%) | In 1 condition |
| OPA3outer mitochondrial membrane lipid metabolism regulator OPA3 | Sometimes (5–29%) | In 1 condition |
| OTX2orthodenticle homeobox 2 | Sometimes (5–29%) | In 1 condition |
| CHMP4Bcharged multivesicular body protein 4B | Not recorded | In 1 condition |
| FOXE3forkhead box E3 | Not recorded | In 1 condition |
| GJA8gap junction protein alpha 8 | Not recorded | In 1 condition |
| OATornithine aminotransferase | Not recorded | In 1 condition |
| SPRTNSprT-like N-terminal domain | Not recorded | In 1 condition |
| TONSLtonsoku like, DNA repair protein | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.19-9814e911.
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