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Trait
Motor neuron atrophy
Wasting involving the motor neuron.
Summary
- Also called
- Motor neuron degeneration
- Body system
- Abnormality of the nervous system
Motor neuron atrophyHP:0007373
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Read the genes linked to Motor neuron atrophy, and the rest of your genome, with one test.
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Get my Genome Test34 genes linked to Motor neuron atrophy
Changes in these genes cause rare conditions in which Motor neuron atrophy is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ANGangiogenin | Very often (80–99%) | In 1 condition |
| ANXA11annexin A11 | Very often (80–99%) | In 1 condition |
| ATXN2ataxin 2 | Very often (80–99%) | In 1 condition |
| CCNFcyclin F | Very often (80–99%) | In 1 condition |
| CFAP410cilia and flagella associated protein 410 | Very often (80–99%) | In 1 condition |
| CHCHD10coiled-coil-helix-coiled-coil-helix domain containing 10 | Very often (80–99%) | In 1 condition |
| CHMP2Bcharged multivesicular body protein 2B | Very often (80–99%) | In 1 condition |
| DAOD-amino acid oxidase | Very often (80–99%) | In 1 condition |
| DCTN1dynactin subunit 1 | Very often (80–99%) | In 1 condition |
| ERBB4erb-b2 receptor tyrosine kinase 4 | Very often (80–99%) | In 1 condition |
| FIG4FIG4 phosphoinositide 5-phosphatase | Very often (80–99%) | In 1 condition |
| FUSFUS RNA binding protein | Very often (80–99%) | In 1 condition |
| GLE1GLE1 RNA export mediator | Very often (80–99%) | In 1 condition |
| GLT8D1glycosyltransferase 8 domain containing 1 | Very often (80–99%) | In 1 condition |
| HNRNPA1heterogeneous nuclear ribonucleoprotein A1 | Very often (80–99%) | In 1 condition |
| LRP12LDL receptor related protein 12 | Very often (80–99%) | In 1 condition |
| MATR3matrin 3 | Very often (80–99%) | In 1 condition |
| NEFHneurofilament heavy chain | Very often (80–99%) | In 1 condition |
| NEK1NIMA related kinase 1 | Very often (80–99%) | In 1 condition |
| OPTNoptineurin | Very often (80–99%) | In 1 condition |
| PFN1profilin 1 | Very often (80–99%) | In 1 condition |
| PRPHperipherin | Very often (80–99%) | In 1 condition |
| SOD1superoxide dismutase 1 | Very often (80–99%) | In 1 condition |
| SQSTM1sequestosome 1 | Very often (80–99%) | In 1 condition |
| TAF15TATA-box binding protein associated factor 15 | Very often (80–99%) | In 1 condition |
| TARDBPTAR DNA binding protein | Very often (80–99%) | In 1 condition |
| TBK1TANK binding kinase 1 | Very often (80–99%) | In 1 condition |
| TREM2triggering receptor expressed on myeloid cells 2 | Very often (80–99%) | In 1 condition |
| UBQLN2ubiquilin 2 | Very often (80–99%) | In 1 condition |
| UNC13Aunc-13 homolog A | Very often (80–99%) | In 1 condition |
| VAPBVAMP associated protein B and C | Very often (80–99%) | In 1 condition |
| VCPvalosin containing protein | Very often (80–99%) | In 1 condition |
| RBM28RNA binding motif protein 28 | Often (30–79%) | In 1 condition |
| PRKAR1Bprotein kinase cAMP-dependent type I regulatory subunit beta | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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