Trait
Blind spot located at fixation point
Clinical name: Central scotoma
An area of depressed vision located at the point of fixation and that interferes with central vision.
Summary
- Also called
- Central blind spot, Central scotomata
- Body system
- Abnormality of the eye
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Blind spot located at fixation point, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test76 genes linked to Blind spot located at fixation point
Changes in these genes cause rare conditions in which Blind spot located at fixation point is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| FDXRferredoxin reductase | Always | In 2 conditions |
| MCATmalonyl-CoA-acyl carrier protein transacylase | Always | In 1 condition |
| MECRmitochondrial trans-2-enoyl-CoA reductase | Always | In 1 condition |
| MFSD8major facilitator superfamily domain containing 8 | Always | In 2 conditions |
| MTRFRmitochondrial translation release factor in rescue | Always | In 1 condition |
| OPA1OPA1 mitochondrial dynamin like GTPase | Always | In 3 conditions |
| POC1BPOC1 centriolar protein B | Always | In 2 conditions |
| RBP3retinol binding protein 3 | Always | In 1 condition |
| UBAP1Lubiquitin associated protein 1 like | Always | In 2 conditions |
| ABCA4ATP binding cassette subfamily A member 4 | Very often (80–99%) | In 3 conditions |
| CNGB3cyclic nucleotide gated channel subunit beta 3 | Very often (80–99%) | In 2 conditions |
| ELOVL4ELOVL fatty acid elongase 4 | Very often (80–99%) | In 1 condition |
| ITM2Bintegral membrane protein 2B | Very often (80–99%) | In 1 condition |
| PROM1prominin 1 | Very often (80–99%) | In 4 conditions |
| PRPH2peripherin 2 | Very often (80–99%) | In 3 conditions |
| ADAM9ADAM metallopeptidase domain 9 | Often (30–79%) | In 1 condition |
| AIPL1AIP like 1 HSP90 co-chaperone | Often (30–79%) | In 1 condition |
| ATF6activating transcription factor 6 | Often (30–79%) | In 3 conditions |
| CACNA1Fcalcium voltage-gated channel subunit alpha1 F | Often (30–79%) | In 2 conditions |
| CACNA2D4calcium voltage-gated channel auxiliary subunit alpha2delta 4 | Often (30–79%) | In 1 condition |
| CDHR1cadherin related family member 1 | Often (30–79%) | In 1 condition |
| CFAP410cilia and flagella associated protein 410 | Often (30–79%) | In 2 conditions |
| CFAP418cilia and flagella associated protein 418 | Often (30–79%) | In 1 condition |
| CLN3CLN3 lysosomal/endosomal transmembrane protein, battenin | Often (30–79%) | In 1 condition |
| CNGA3cyclic nucleotide gated channel subunit alpha 3 | Often (30–79%) | In 2 conditions |
| CRXcone-rod homeobox | Often (30–79%) | In 2 conditions |
| DNAJC30DnaJ heat shock protein family (Hsp40) member C30 | Often (30–79%) | In 1 condition |
| DNM1Ldynamin 1L | Often (30–79%) | In 2 conditions |
| DRAM2DNA damage regulated autophagy modulator 2 | Often (30–79%) | In 1 condition |
| FSD1Lfibronectin type III and SPRY domain containing 1 like | Often (30–79%) | In 1 condition |
| GNAT2G protein subunit alpha transducin 2 | Often (30–79%) | In 1 condition |
| GUCA1Aguanylate cyclase activator 1A | Often (30–79%) | In 1 condition |
| GUCY2Dguanylate cyclase 2D, retinal | Often (30–79%) | In 1 condition |
| MT-ATP6mitochondrially encoded ATP synthase membrane subunit 6 | Often (30–79%) | In 1 condition |
| MT-CO1mitochondrially encoded cytochrome c oxidase I | Often (30–79%) | In 1 condition |
| MT-CO3mitochondrially encoded cytochrome c oxidase III | Often (30–79%) | In 1 condition |
| MT-CYBmitochondrially encoded cytochrome b | Often (30–79%) | In 1 condition |
| MT-ND1mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 | Often (30–79%) | In 1 condition |
| MT-ND2mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 | Often (30–79%) | In 1 condition |
| MT-ND4mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 | Often (30–79%) | In 1 condition |
Show 36 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| MT-ND4Lmitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L | Often (30–79%) | In 1 condition |
| MT-ND5mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 | Often (30–79%) | In 1 condition |
| MT-ND6mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 | Often (30–79%) | In 1 condition |
| NDUFS2NADH:ubiquinone oxidoreductase core subunit S2 | Often (30–79%) | In 1 condition |
| NMNAT1nicotinamide nucleotide adenylyltransferase 1 | Often (30–79%) | In 1 condition |
| OPA3outer mitochondrial membrane lipid metabolism regulator OPA3 | Often (30–79%) | In 1 condition |
| OPN1LWopsin 1, long wave sensitive | Often (30–79%) | In 1 condition |
| OPN1MWopsin 1, medium wave sensitive | Often (30–79%) | In 1 condition |
| PDE6Cphosphodiesterase 6C | Often (30–79%) | In 1 condition |
| PDE6Hphosphodiesterase 6H | Often (30–79%) | In 1 condition |
| PITPNM3PITPNM family member 3 | Often (30–79%) | In 2 conditions |
| RAB28RAB28, member RAS oncogene family | Often (30–79%) | In 2 conditions |
| RAX2retina and anterior neural fold homeobox 2 | Often (30–79%) | In 1 condition |
| RDH5retinol dehydrogenase 5 | Often (30–79%) | In 1 condition |
| RHOrhodopsin | Often (30–79%) | In 1 condition |
| RIMS1regulating synaptic membrane exocytosis 1 | Often (30–79%) | In 1 condition |
| RLBP1retinaldehyde binding protein 1 | Often (30–79%) | In 3 conditions |
| RP2RP2 activator of ARL3 GTPase | Often (30–79%) | In 1 condition |
| RPGRretinitis pigmentosa GTPase regulator | Often (30–79%) | In 2 conditions |
| RPGRIP1RPGR interacting protein 1 | Often (30–79%) | In 1 condition |
| RTN4IP1reticulon 4 interacting protein 1 | Often (30–79%) | In 1 condition |
| SEMA4Asemaphorin 4A | Often (30–79%) | In 1 condition |
| TLCD3BTLC domain containing 3B | Often (30–79%) | In 1 condition |
| TTLL5tubulin tyrosine ligase like 5 | Often (30–79%) | In 1 condition |
| UNC119unc-119 lipid binding chaperone | Often (30–79%) | In 1 condition |
| CYP4V2cytochrome P450 family 4 subfamily V member 2 | Sometimes (5–29%) | In 1 condition |
| HGSNATheparan-alpha-glucosaminide N-acetyltransferase | Sometimes (5–29%) | In 1 condition |
| PPIBpeptidylprolyl isomerase B | Sometimes (5–29%) | In 1 condition |
| SAMD7sterile alpha motif domain containing 7 | Sometimes (5–29%) | In 1 condition |
| TIMM8Atranslocase of inner mitochondrial membrane 8A | Sometimes (5–29%) | In 1 condition |
| CYP1B1cytochrome P450 family 1 subfamily B member 1 | Rarely (1–4%) | In 1 condition |
| EFEMP1EGF-like fibulin extracellular matrix protein 1 | Rarely (1–4%) | In 1 condition |
| MYOCmyocilin | Rarely (1–4%) | In 1 condition |
| IMPG2interphotoreceptor matrix proteoglycan 2 | Not recorded | In 1 condition |
| MFN2mitofusin 2 | Not recorded | In 1 condition |
| TMEM126Atransmembrane protein 126A | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks