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Gene

TRPM2

transient receptor potential cation channel subfamily M member 2

Summary

Cytogenetic location
21q22.3
Coordinates
Chromosome 21: 44,353,621–44,442,644 (GRCh38)
Exons
32 exons across 89 kb
Protein
1,503 amino acids
Also known as
KNP3, LTRPC2, NUDT9L1, NUDT9H, EREG1
Previous symbols
TRPC7
MANE Select transcript
ENST00000397928.6NM_003307.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TRPM2 yet. The test sequences your whole genome, so your data includes it all the same.

How TRPM2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 21, with a bracket where TRPM2 sits. TRPM2 and 32 genes near it on chromosome 21, from 43,898,133 to 44,898,132.Chromosome 2121q22.3p13p12p11.2p11.1q11.1q11.2q21.1q21.2q21.3q22.11q22.12q22.13q22.2q22.344 Mb44.2 Mb44.4 Mb44.6 Mb44.8 MbAGPAT3: 43,865,081–43,987,592, forward strandAGPAT3: 43,939,919–43,959,673, forward strandTRAPPC10: 44,012,280–44,106,553, forward strandTRAPPC10PWP2: 44,107,306–44,131,181, forward strandPWP2GATD3: 44,133,610–44,210,114, forward strandGATD3ICOSLG: 44,215,382–44,241,446, reverse strandICOSLGDNMT3L: 44,246,339–44,262,216, reverse strandDNMT3LAIRE: 44,285,838–44,298,648, forward strandAIREPFKL: 44,300,017–44,327,377, forward strandPFKLCFAP410: 44,328,943–44,339,427, reverse strandCFAP410TRPM2: 44,353,621–44,442,644, forward strandTRPM2LRRC3: 44,455,472–44,463,452, forward strandLRRC3TSPEAR: 44,497,893–44,712,286, reverse strandKRTAP10-1: 44,538,981–44,540,195, reverse strandKRTAP10-1KRTAP10-2: 44,550,357–44,551,505, reverse strandKRTAP10-2KRTAP10-3: 44,557,790–44,558,795, reverse strandKRTAP10-3KRTAP10-4: 44,573,729–44,575,371, forward strandKRTAP10-4KRTAP10-5: 44,579,455–44,580,604, reverse strandKRTAP10-6: 44,591,268–44,592,505, reverse strandKRTAP10-7: 44,600,597–44,602,174, forward strandKRTAP10-8: 44,612,079–44,612,954, forward strandKRTAP10-9: 44,627,093–44,628,378, forward strandKRTAP10-10: 44,637,356–44,638,455, forward strandKRTAP10-11: 44,646,414–44,647,650, forward strandKRTAP12-4: 44,654,213–44,654,659, reverse strandKRTAP12-4KRTAP12-3: 44,657,932–44,658,341, forward strandKRTAP12-2: 44,666,189–44,666,927, reverse strandKRTAP12-2KRTAP12-1: 44,681,576–44,682,163, reverse strandKRTAP10-12: 44,697,172–44,698,044, forward strandUBE2G2: 44,768,580–44,801,826, reverse strandUBE2G2SUMO3: 44,805,604–44,818,779, reverse strandSUMO3PTTG1IP: 44,849,585–44,873,903, reverse strandPTTG1IPITGB2: 44,885,948–44,932,079, reverse strandITGB2Diagram of TRPM2: 32 exons on the forward strand of chromosome 21Exon 1: 44,353,621–44,353,865, 245 basesExon 2: 44,354,648–44,354,736, 89 basesExon 3: 44,364,114–44,364,282, 169 basesExon 4: 44,366,754–44,366,934, 181 basesExon 5: 44,369,177–44,369,343, 167 basesExon 6: 44,375,833–44,376,013, 181 basesExon 7: 44,377,712–44,377,773, 62 basesExon 8: 44,378,997–44,379,197, 201 basesExon 9: 44,382,718–44,382,820, 103 basesExon 10: 44,390,904–44,391,025, 122 basesExon 11: 44,391,272–44,391,625, 354 basesExon 12: 44,395,414–44,395,551, 138 basesExon 13: 44,397,747–44,397,876, 130 basesExon 14: 44,399,296–44,399,441, 146 basesExon 15: 44,400,259–44,400,371, 113 basesExon 16: 44,401,681–44,401,897, 217 basesExon 17: 44,405,142–44,405,260, 119 basesExon 18: 44,405,905–44,406,037, 133 basesExon 19: 44,406,594–44,406,765, 172 basesExon 20: 44,413,891–44,414,074, 184 basesExon 21: 44,417,927–44,418,108, 182 basesExon 22: 44,418,423–44,418,555, 133 basesExon 23: 44,423,645–44,423,732, 88 basesExon 24: 44,424,852–44,424,939, 88 basesExon 25: 44,425,670–44,425,827, 158 basesExon 26: 44,426,660–44,426,736, 77 basesExon 27: 44,427,010–44,427,111, 102 basesExon 28: 44,435,131–44,435,217, 87 basesExon 29: 44,437,062–44,437,167, 106 basesExon 30: 44,439,067–44,439,168, 102 basesExon 31: 44,440,789–44,440,905, 117 basesExon 32: 44,441,692–44,442,644, 953 bases151015202530325′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.4 kb of the gene's 89 kb; 4,512 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TRPM2 gene: transient receptor potential cation channel subfamily M member 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/trpm2

Vancouver

Dante Labs. TRPM2 gene: transient receptor potential cation channel subfamily M member 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/trpm2

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