Trait
Increased calcium level in kidney
Clinical name: Nephrocalcinosis
Nephrocalcinosis is the deposition of calcium salts in renal parenchyma.
Summary
- Also called
- Too much calcium deposited in kidneys
- Body system
- Abnormality of the genitourinary system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Increased calcium level in kidney, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test97 genes linked to Increased calcium level in kidney
Changes in these genes cause rare conditions in which Increased calcium level in kidney is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AGXTalanine--glyoxylate aminotransferase | Always | In 2 conditions |
| AMMECR1AMMECR nuclear protein 1 | Always | In 1 condition |
| CLCN5Cl-/H+ antiporter 5 | Always | In 4 conditions |
| CLDN16claudin 16 | Always | In 1 condition |
| CLDN19claudin 19 | Always | In 1 condition |
| PEX3peroxisomal biogenesis factor 3 | Always | In 1 condition |
| SLC34A1solute carrier family 34 member 1 | Always | In 1 condition |
| SPOUT1SPOUT domain containing methyltransferase 1 | Always | In 1 condition |
| TRA2Btransformer 2 beta homolog | Always | In 1 condition |
| ATP6V0A4ATPase H+ transporting V0 subunit a4 | Very often (80–99%) | In 1 condition |
| CDC73cell division cycle 73 | Very often (80–99%) | In 3 conditions |
| CLPBClpB family mitochondrial disaggregase | Very often (80–99%) | In 1 condition |
| FAM20AFAM20A golgi associated secretory pathway pseudokinase | Very often (80–99%) | In 2 conditions |
| GCM2GCM transcription factor 2 | Very often (80–99%) | In 1 condition |
| GRHPRglyoxylate and hydroxypyruvate reductase | Very often (80–99%) | In 2 conditions |
| HOGA14-hydroxy-2-oxoglutarate aldolase 1 | Very often (80–99%) | In 1 condition |
| KCNJ1potassium inwardly rectifying channel subfamily J member 1 | Very often (80–99%) | In 1 condition |
| MEN1menin 1 | Very often (80–99%) | In 1 condition |
| SLC12A1solute carrier family 12 member 1 | Very often (80–99%) | In 1 condition |
| ABCC6ATP binding cassette subfamily C member 6 | Often (30–79%) | In 3 conditions |
| ATP1A1ATPase Na+/K+ transporting subunit alpha 1 | Often (30–79%) | In 1 condition |
| ATP6V1E1ATPase H+ transporting V1 subunit E1 | Often (30–79%) | In 1 condition |
| CASRcalcium sensing receptor | Often (30–79%) | In 2 conditions |
| ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 1 | Often (30–79%) | In 2 conditions |
| FUT8fucosyltransferase 8 | Often (30–79%) | In 1 condition |
| GEMIN4gem nuclear organelle associated protein 4 | Often (30–79%) | In 1 condition |
| GNA11G protein subunit alpha 11 | Often (30–79%) | In 1 condition |
| HPRT1hypoxanthine phosphoribosyltransferase 1 | Often (30–79%) | In 1 condition |
| HSD11B2hydroxysteroid 11-beta dehydrogenase 2 | Often (30–79%) | In 1 condition |
| MYO5Bmyosin VB | Often (30–79%) | In 1 condition |
| OXGR1oxoglutarate receptor 1 | Often (30–79%) | In 1 condition |
| PHEXphosphate regulating endopeptidase X-linked | Often (30–79%) | In 1 condition |
| PIGTphosphatidylinositol glycan anchor biosynthesis class T | Often (30–79%) | In 2 conditions |
| PIK3C2Aphosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha | Often (30–79%) | In 1 condition |
| PTHparathyroid hormone | Often (30–79%) | In 1 condition |
| ROR2ROR family WNT receptor 2 | Often (30–79%) | In 1 condition |
| RRAGDRas related GTP binding D | Often (30–79%) | In 2 conditions |
| SLC1A2solute carrier family 1 member 2 | Often (30–79%) | In 1 condition |
| SLC4A1solute carrier family 4 member 1 (Diego blood group) | Often (30–79%) | In 2 conditions |
| SLC7A7solute carrier family 7 member 7 | Often (30–79%) | In 1 condition |
Show 57 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| STX3syntaxin 3 | Often (30–79%) | In 1 condition |
| TRNT1tRNA nucleotidyl transferase 1 | Often (30–79%) | In 1 condition |
| VPS33BVPS33B late endosome and lysosome associated | Often (30–79%) | In 2 conditions |
| AIREautoimmune regulator | Sometimes (5–29%) | In 1 condition |
| ATP6V1B2ATPase H+ transporting V1 subunit B2 | Sometimes (5–29%) | In 1 condition |
| BAZ1Bbromodomain adjacent to zinc finger domain 1B | Sometimes (5–29%) | In 1 condition |
| BSNDbarttin CLCNK type accessory subunit beta | Sometimes (5–29%) | In 1 condition |
| BTNL2butyrophilin like 2 | Sometimes (5–29%) | In 1 condition |
| BUD23BUD23 rRNA methyltransferase and ribosome maturation factor | Sometimes (5–29%) | In 1 condition |
| CLCNKAchloride voltage-gated channel Ka | Sometimes (5–29%) | In 1 condition |
| CLCNKBchloride voltage-gated channel Kb | Sometimes (5–29%) | In 1 condition |
| CLIP2CAP-Gly domain containing linker protein 2 | Sometimes (5–29%) | In 1 condition |
| DNAJC30DnaJ heat shock protein family (Hsp40) member C30 | Sometimes (5–29%) | In 1 condition |
| DYNC2I2dynein 2 intermediate chain 2 | Sometimes (5–29%) | In 1 condition |
| EIF4Heukaryotic translation initiation factor 4H | Sometimes (5–29%) | In 1 condition |
| ELNelastin | Sometimes (5–29%) | In 2 conditions |
| FKBP6FKBP prolyl isomerase family member 6 (inactive) | Sometimes (5–29%) | In 1 condition |
| GTF2Igeneral transcription factor IIi | Sometimes (5–29%) | In 1 condition |
| GTF2IRD1GTF2I repeat domain containing 1 | Sometimes (5–29%) | In 1 condition |
| GTF2IRD2GTF2I repeat domain containing 2 | Sometimes (5–29%) | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Sometimes (5–29%) | In 1 condition |
| INSRinsulin receptor | Sometimes (5–29%) | In 2 conditions |
| LIMK1LIM domain kinase 1 | Sometimes (5–29%) | In 1 condition |
| MEFVMEFV innate immunity regulator, pyrin | Sometimes (5–29%) | In 1 condition |
| METTL27methyltransferase like 27 | Sometimes (5–29%) | In 1 condition |
| MLXIPLMLX interacting protein like | Sometimes (5–29%) | In 1 condition |
| MPV17mitochondrial inner membrane protein MPV17 | Sometimes (5–29%) | In 1 condition |
| NCF1neutrophil cytosolic factor 1 | Sometimes (5–29%) | In 1 condition |
| OCRLOCRL inositol polyphosphate-5-phosphatase | Sometimes (5–29%) | In 2 conditions |
| PTH1Rparathyroid hormone 1 receptor | Sometimes (5–29%) | In 2 conditions |
| RFC2replication factor C subunit 2 | Sometimes (5–29%) | In 1 condition |
| SLC2A2solute carrier family 2 member 2 | Sometimes (5–29%) | In 1 condition |
| SLC37A4solute carrier family 37 member 4 | Sometimes (5–29%) | In 1 condition |
| SRCAPSnf2 related CREBBP activator protein | Sometimes (5–29%) | In 2 conditions |
| STRADASTE20 related adaptor alpha | Sometimes (5–29%) | In 2 conditions |
| STX1Asyntaxin 1A | Sometimes (5–29%) | In 1 condition |
| TBC1D24TBC1 domain family member 24 | Sometimes (5–29%) | In 1 condition |
| TBL2transducin beta like 2 | Sometimes (5–29%) | In 1 condition |
| TMEM270transmembrane protein 270 | Sometimes (5–29%) | In 1 condition |
| VIPAS39VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog | Sometimes (5–29%) | In 2 conditions |
| VPS37DVPS37D subunit of ESCRT-I | Sometimes (5–29%) | In 1 condition |
| ZFXzinc finger protein X-linked | Sometimes (5–29%) | In 1 condition |
| ZNF687zinc finger protein 687 | Sometimes (5–29%) | In 1 condition |
| ALPLalkaline phosphatase, biomineralization associated | Not recorded | In 1 condition |
| CDKN1Ccyclin dependent kinase inhibitor 1C | Not recorded | In 1 condition |
| COL4A3collagen type IV alpha 3 chain | Not recorded | In 1 condition |
| CYP24A1cytochrome P450 family 24 subfamily A member 1 | Not recorded | In 1 condition |
| DNAJC21DnaJ heat shock protein family (Hsp40) member C21 | Not recorded | In 1 condition |
| FAHfumarylacetoacetate hydrolase | Not recorded | In 1 condition |
| GALNT3polypeptide N-acetylgalactosaminyltransferase 3 | Not recorded | In 1 condition |
| GATA3GATA binding protein 3 | Not recorded | In 1 condition |
| HNF4Ahepatocyte nuclear factor 4 alpha | Not recorded | In 1 condition |
| IGF2insulin like growth factor 2 | Not recorded | In 1 condition |
| KCNQ1potassium voltage-gated channel subfamily Q member 1 | Not recorded | In 1 condition |
| KCNQ1OT1KCNQ1 opposite strand/antisense transcript 1 | Not recorded | In 1 condition |
| SBDSSBDS ribosome maturation factor | Not recorded | In 1 condition |
| SRP54signal recognition particle 54 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks