Trait

Abnormally shaped kidney

Clinical name: Abnormal renal morphology

Any structural anomaly of the kidney.

HPO HP:0012210

Also called: Kidney malformation, Kidney structure issue, Structural kidney abnormalities, Abnormal kidney morphology, Renal malformation, Structural anomalies of the renal tract, Structural renal anomalies
Body system: Abnormality of the genitourinary system

Read the genes linked to Abnormally shaped kidney, and the rest of your genome, with one test.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test

40 genes linked to Abnormally shaped kidney

Changes in these genes cause rare conditions in which Abnormally shaped kidney is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
BRCA1BRCA1 DNA repair associated	Often (30–79%)	In 1 condition
BRCA2BRCA2 DNA repair associated	Often (30–79%)	In 1 condition
BRIP1BRCA1 interacting DNA helicase 1	Often (30–79%)	In 1 condition
ELNelastin	Often (30–79%)	In 1 condition
ERCC4ERCC excision repair 4, endonuclease catalytic subunit	Often (30–79%)	In 1 condition
FAAP100FA core complex associated protein 100	Often (30–79%)	In 1 condition
FANCAFA complementation group A	Often (30–79%)	In 2 conditions
FANCBFA complementation group B	Often (30–79%)	In 1 condition
FANCCFA complementation group C	Often (30–79%)	In 1 condition
FANCD2FA complementation group D2	Often (30–79%)	In 1 condition
FANCEFA complementation group E	Often (30–79%)	In 1 condition
FANCFFA complementation group F	Often (30–79%)	In 1 condition
FANCGFA complementation group G	Often (30–79%)	In 1 condition
FANCIFA complementation group I	Often (30–79%)	In 2 conditions
FANCLFA complementation group L	Often (30–79%)	In 1 condition
FANCMFA complementation group M	Often (30–79%)	In 1 condition
MAD2L2mitotic arrest deficient 2 like 2	Often (30–79%)	In 1 condition
MLXIPLMLX interacting protein like	Often (30–79%)	In 1 condition
PALB2partner and localizer of BRCA2	Often (30–79%)	In 1 condition
RAD51RAD51 recombinase	Often (30–79%)	In 1 condition
RAD51CRAD51 paralog C	Often (30–79%)	In 1 condition
RAI1retinoic acid induced 1	Often (30–79%)	In 3 conditions
RFWD3ring finger and WD repeat domain 3	Often (30–79%)	In 1 condition
SLX4SLX4 structure-specific endonuclease subunit	Often (30–79%)	In 1 condition
UBE2Tubiquitin conjugating enzyme E2 T	Often (30–79%)	In 1 condition
XRCC2X-ray repair cross complementing 2	Often (30–79%)	In 1 condition
ADGRG2adhesion G protein-coupled receptor G2	Sometimes (5–29%)	In 1 condition
CFTRCF transmembrane conductance regulator	Sometimes (5–29%)	In 1 condition
DACT1dishevelled binding antagonist of beta catenin 1	Sometimes (5–29%)	In 1 condition
HNF1BHNF1 homeobox B	Sometimes (5–29%)	In 1 condition
NF1neurofibromin 1	Sometimes (5–29%)	In 1 condition
PACS1phosphofurin acidic cluster sorting protein 1	Sometimes (5–29%)	In 1 condition
SALL1spalt like transcription factor 1	Sometimes (5–29%)	In 1 condition
GLMNglomulin, FKBP associated protein	Rarely (1–4%)	In 1 condition
PAHphenylalanine hydroxylase	Rarely (1–4%)	In 1 condition
SLC35A2solute carrier family 35 member A2	Rarely (1–4%)	In 1 condition
FGFR2fibroblast growth factor receptor 2	Not recorded	In 1 condition
FLCNfolliculin	Not recorded	In 1 condition
PIGVphosphatidylinositol glycan anchor biosynthesis class V	Not recorded	In 1 condition
PORcytochrome p450 oxidoreductase	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormality of the kidney

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

One test. A lifetime of answers.