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Gene

RRAGD

Ras related GTP binding D

Summary

Cytogenetic location
6q15
Coordinates
Chromosome 6: 89,364,616–89,412,273 (GRCh38)
Exons
7 exons across 47.7 kb
Protein
400 amino acids
Also known as
DKFZP761H171, bA11D8.2.1
MANE Select transcript
ENST00000369415.9NM_021244.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

  • Familial Hypomagnesemia

    • Familial Primary Hypomagnesemia

      A group of inherited magnesium-wasting disorders caused by variants in genes such as CLDN16, CLDN19, TRPM6, CNNM2 and FXYD2; the CLDN16 and CLDN19 forms can progress to chronic kidney disease.

      • 1 GenCC submitter rates it definitive or strong
      What knowing changes

      Magnesium supplementation can control symptoms, and some forms need kidney function and eye monitoring.

How RRAGD is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 6, with a bracket where RRAGD sits. RRAGD and 11 genes near it on chromosome 6, from 88,888,445 to 89,888,444.Chromosome 66q15p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12q13q14.1q14.2q14.3q15q16.1q16.2q16.3q21q22.1q22.2q22.31q22.32q22.33q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q26q2789 Mb89.2 Mb89.4 Mb89.6 Mb89.8 MbRNGTT: 88,607,995–88,963,636, reverse strandRNGTTPNRC1: 89,080,747–89,087,711, forward strandPNRC1SRSF12: 89,093,949–89,118,086, reverse strandSRSF12PM20D2: 89,145,999–89,165,565, forward strandPM20D2GABRR1: 89,177,504–89,231,278, reverse strandGABRR1GABRR2: 89,254,464–89,315,299, reverse strandGABRR2UBE2J1: 89,321,391–89,353,180, reverse strandUBE2J1RRAGD: 89,364,616–89,412,273, reverse strandRRAGDANKRD6: 89,433,119–89,634,170, forward strandANKRD6LYRM2: 89,568,144–89,638,761, reverse strandLYRM2MDN1: 89,642,498–89,819,809, reverse strandMDN1CASP8AP2: 89,829,894–89,874,436, forward strandCASP8AP2Diagram of RRAGD: 7 exons on the reverse strand of chromosome 6Exon 2: 1 known disease-causing siteExon 7: 89,364,616–89,368,207, 3,592 basesExon 6: 89,372,437–89,372,585, 149 basesExon 5: 89,377,671–89,377,813, 143 basesExon 4: 89,379,224–89,379,338, 115 basesExon 3: 89,380,168–89,380,367, 200 basesExon 2: 89,387,295–89,387,590, 296 basesExon 1: 89,411,846–89,412,273, 428 bases76543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.9 kb of the gene's 47.7 kb; 1,203 of those bases code for the protein.

How a genome test reads RRAGD

1

position in RRAGD where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 47.7 kb of RRAGD, introns included, not only the 4.9 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). RRAGD gene: Ras related GTP binding D. Retrieved 16 October 2026, from https://dantelabs.com/genes/rragd

Vancouver

Dante Labs. RRAGD gene: Ras related GTP binding D [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/rragd

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