Skip to content
Use your HSA or FSA funds

Gene

DKK1

dickkopf Wnt signaling pathway inhibitor 1

Summary

Cytogenetic location
10q21.1
Coordinates
Chromosome 10: 52,314,281–52,317,657 (GRCh38)
Exons
4 exons across 3.4 kb
Protein
266 amino acids
Also known as
SK, DKK-1
MANE Select transcript
ENST00000373970.4NM_012242.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DKK1 yet. The test sequences your whole genome, so your data includes it all the same.

How DKK1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 10, with a bracket where DKK1 sits. DKK1 and 2 genes near it on chromosome 10, from 51,815,969 to 52,815,968.Chromosome 1010q21.1p15.3p15.2p15.1p14p13p12.33p12.32p12.31p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.31q23.32q23.33q24.1q24.2q24.31q24.32q24.33q25.1q25.2q25.3q26.11q26.12q26.13q26.2q26.352 Mb52.2 Mb52.4 Mb52.6 Mb52.8 MbPRKG1: 50,990,888–52,298,423, forward strandPRKG1DKK1: 52,314,281–52,317,657, forward strandDKK1MBL2: 52,758,075–52,773,009, reverse strandMBL2Diagram of DKK1: 4 exons on the forward strand of chromosome 10Exon 1: 52,314,281–52,314,677, 397 basesExon 2: 52,314,923–52,315,085, 163 basesExon 3: 52,316,295–52,316,435, 141 basesExon 4: 52,316,554–52,317,657, 1,104 bases12345′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.8 kb of the gene's 3.4 kb; 801 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). DKK1 gene: dickkopf Wnt signaling pathway inhibitor 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/dkk1

Vancouver

Dante Labs. DKK1 gene: dickkopf Wnt signaling pathway inhibitor 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/dkk1

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test