Trait
Cough
A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation.
Summary
- Also called
- Coughing
- Body system
- Abnormality of the respiratory system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test118 genes linked to Cough
Changes in these genes cause rare conditions in which Cough is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| BMPR2bone morphogenetic protein receptor type 2 | Always | In 1 condition |
| CCDC39coiled-coil domain 39 molecular ruler complex subunit | Always | In 1 condition |
| CCDC40coiled-coil domain 40 molecular ruler complex subunit | Always | In 1 condition |
| CFAP52cilia and flagella associated protein 52 | Always | In 1 condition |
| CYBBcytochrome b-245 beta chain | Always | In 1 condition |
| DNAAF6dynein axonemal assembly factor 6 | Always | In 1 condition |
| DNAH11dynein axonemal heavy chain 11 | Always | In 1 condition |
| DNAH9dynein axonemal heavy chain 9 | Always | In 1 condition |
| FARSAphenylalanyl-tRNA synthetase subunit alpha | Always | In 1 condition |
| FARSBphenylalanyl-tRNA synthetase subunit beta | Always | In 1 condition |
| FDXRferredoxin reductase | Always | In 1 condition |
| FEM1Bfem-1 homolog B | Always | In 1 condition |
| IFT140intraflagellar transport 140 | Always | In 1 condition |
| ITPR3inositol 1,4,5-trisphosphate receptor type 3 | Always | In 1 condition |
| LRRC56leucine rich repeat containing 56 | Always | In 1 condition |
| NHEJ1non-homologous end joining factor 1 | Always | In 1 condition |
| SERPINA1serpin family A member 1 | Always | In 1 condition |
| SLC13A1solute carrier family 13 member 1 | Always | In 1 condition |
| SLC41A1solute carrier family 41 member 1 | Always | In 1 condition |
| UNC13Aunc-13 homolog A | Always | In 1 condition |
| WASWASP actin nucleation promoting factor | Always | In 1 condition |
| WFDC2WAP four-disulfide core domain 2 | Always | In 1 condition |
| BLNKB cell linker | Very often (80–99%) | In 1 condition |
| CD79ACD79a molecule | Very often (80–99%) | In 1 condition |
| CD79BCD79b molecule | Very often (80–99%) | In 1 condition |
| IGHMimmunoglobulin heavy constant mu | Very often (80–99%) | In 1 condition |
| IGLL1immunoglobulin lambda like polypeptide 1 | Very often (80–99%) | In 1 condition |
| LRRC8Aleucine rich repeat containing 8 VRAC subunit A | Very often (80–99%) | In 1 condition |
| PIK3CDphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Very often (80–99%) | In 1 condition |
| PIK3R1phosphoinositide-3-kinase regulatory subunit 1 | Very often (80–99%) | In 1 condition |
| SPI1Spi-1 proto-oncogene | Very often (80–99%) | In 1 condition |
| TCF3transcription factor 3 | Very often (80–99%) | In 1 condition |
| TERTtelomerase reverse transcriptase | Very often (80–99%) | In 3 conditions |
| TFGtrafficking from ER to golgi regulator | Very often (80–99%) | In 1 condition |
| TSC1TSC complex subunit 1 | Very often (80–99%) | In 1 condition |
| TSC2TSC complex subunit 2 | Very often (80–99%) | In 1 condition |
| AAASaladin WD repeat nucleoporin | Often (30–79%) | In 1 condition |
| ABCA3ATP binding cassette subfamily A member 3 | Often (30–79%) | In 2 conditions |
| ACAT1acetyl-CoA acetyltransferase 1 | Often (30–79%) | In 1 condition |
| AGR2anterior gradient 2, protein disulphide isomerase family member | Often (30–79%) | In 1 condition |
Show 78 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| ATP11AATPase phospholipid transporting 11A | Often (30–79%) | In 1 condition |
| BAP1BRCA1 associated deubiquitinase 1 | Often (30–79%) | In 1 condition |
| BTNL2butyrophilin like 2 | Often (30–79%) | In 1 condition |
| CRLF1cytokine receptor like factor 1 | Often (30–79%) | In 1 condition |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Often (30–79%) | In 1 condition |
| DLEC1DLEC1 cilia and flagella associated protein | Often (30–79%) | In 1 condition |
| DNASE1L3deoxyribonuclease 1L3 | Often (30–79%) | In 1 condition |
| DPP9dipeptidyl peptidase 9 | Often (30–79%) | In 1 condition |
| DSPdesmoplakin | Often (30–79%) | In 1 condition |
| ERBB2erb-b2 receptor tyrosine kinase 2 | Often (30–79%) | In 1 condition |
| FAM13Afamily with sequence similarity 13 member A | Often (30–79%) | In 1 condition |
| GBA1glucosylceramidase beta 1 | Often (30–79%) | In 1 condition |
| GMPPAGDP-mannose pyrophosphorylase A | Often (30–79%) | In 1 condition |
| HLA-DPA1major histocompatibility complex, class II, DP alpha 1 | Often (30–79%) | In 1 condition |
| HLA-DPB1major histocompatibility complex, class II, DP beta 1 | Often (30–79%) | In 2 conditions |
| HLA-DQA1major histocompatibility complex, class II, DQ alpha 1 | Often (30–79%) | In 1 condition |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Often (30–79%) | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Often (30–79%) | In 4 conditions |
| IL2RGinterleukin 2 receptor subunit gamma | Often (30–79%) | In 1 condition |
| LAMP2lysosome associated membrane protein 2 | Often (30–79%) | In 1 condition |
| MAP2K1mitogen-activated protein kinase kinase 1 | Often (30–79%) | In 1 condition |
| MUC5Bmucin 5B, oligomeric mucus/gel-forming | Often (30–79%) | In 2 conditions |
| NOS1nitric oxide synthase 1 | Often (30–79%) | In 1 condition |
| NRASNRAS proto-oncogene, GTPase | Often (30–79%) | In 1 condition |
| PARNpoly(A)-specific ribonuclease | Often (30–79%) | In 2 conditions |
| PRTN3proteinase 3 | Often (30–79%) | In 1 condition |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Often (30–79%) | In 2 conditions |
| RFC1replication factor C subunit 1 | Often (30–79%) | In 1 condition |
| RNF6ring finger protein 6 | Often (30–79%) | In 1 condition |
| RTEL1regulator of telomere elongation helicase 1 | Often (30–79%) | In 1 condition |
| SFTPA1surfactant protein A1 | Often (30–79%) | In 2 conditions |
| SFTPA2surfactant protein A2 | Often (30–79%) | In 2 conditions |
| SFTPCsurfactant protein C | Often (30–79%) | In 3 conditions |
| SP110SP110 nuclear body protein | Often (30–79%) | In 1 condition |
| STAT1signal transducer and activator of transcription 1 | Often (30–79%) | In 1 condition |
| STAT3signal transducer and activator of transcription 3 | Often (30–79%) | In 1 condition |
| STN1STN1 subunit of CST complex | Often (30–79%) | In 1 condition |
| TERCtelomerase RNA component | Often (30–79%) | In 2 conditions |
| TGFBR2transforming growth factor beta receptor 2 | Often (30–79%) | In 1 condition |
| TRAPPC11trafficking protein particle complex subunit 11 | Often (30–79%) | In 1 condition |
| WWOXWW domain containing oxidoreductase | Often (30–79%) | In 1 condition |
| ATL1atlastin GTPase 1 | Sometimes (5–29%) | In 1 condition |
| ATL3atlastin GTPase 3 | Sometimes (5–29%) | In 1 condition |
| CD4CD4 molecule | Sometimes (5–29%) | In 1 condition |
| CLEC7AC-type lectin domain containing 7A | Sometimes (5–29%) | In 1 condition |
| COL4A5collagen type IV alpha 5 chain | Sometimes (5–29%) | In 1 condition |
| COL4A6collagen type IV alpha 6 chain | Sometimes (5–29%) | In 1 condition |
| COPAcoat protein complex I subunit alpha | Sometimes (5–29%) | In 1 condition |
| CSF2RAcolony stimulating factor 2 receptor subunit alpha | Sometimes (5–29%) | In 1 condition |
| CSF2RBcolony stimulating factor 2 receptor subunit beta | Sometimes (5–29%) | In 1 condition |
| EPORerythropoietin receptor | Sometimes (5–29%) | In 1 condition |
| FOCADfocadhesin | Sometimes (5–29%) | In 1 condition |
| HLA-Bmajor histocompatibility complex, class I, B | Sometimes (5–29%) | In 2 conditions |
| IKZF1IKAROS family zinc finger 1 | Sometimes (5–29%) | In 1 condition |
| IL17Finterleukin 17F | Sometimes (5–29%) | In 1 condition |
| IL17RAinterleukin 17 receptor A | Sometimes (5–29%) | In 1 condition |
| IL17RCinterleukin 17 receptor C | Sometimes (5–29%) | In 1 condition |
| IRF4interferon regulatory factor 4 | Sometimes (5–29%) | In 1 condition |
| LPIN2lipin 2 | Sometimes (5–29%) | In 1 condition |
| MARS1methionyl-tRNA synthetase 1 | Sometimes (5–29%) | In 1 condition |
| MT-CYBmitochondrially encoded cytochrome b | Sometimes (5–29%) | In 1 condition |
| P4HA2prolyl 4-hydroxylase subunit alpha 2 | Sometimes (5–29%) | In 1 condition |
| PANK2pantothenate kinase 2 | Sometimes (5–29%) | In 1 condition |
| PMP22peripheral myelin protein 22 | Sometimes (5–29%) | In 1 condition |
| POMT1protein O-mannosyltransferase 1 | Sometimes (5–29%) | In 1 condition |
| PRIM1DNA primase subunit 1 | Sometimes (5–29%) | In 1 condition |
| SCNN1Asodium channel epithelial 1 subunit alpha | Sometimes (5–29%) | In 1 condition |
| SCNN1Bsodium channel epithelial 1 subunit beta | Sometimes (5–29%) | In 1 condition |
| SCNN1Gsodium channel epithelial 1 subunit gamma | Sometimes (5–29%) | In 1 condition |
| SPTLC1serine palmitoyltransferase long chain base subunit 1 | Sometimes (5–29%) | In 1 condition |
| SPTLC2serine palmitoyltransferase long chain base subunit 2 | Sometimes (5–29%) | In 1 condition |
| TRAF3IP2TRAF3 interacting protein 2 | Sometimes (5–29%) | In 1 condition |
| DNAAF19dynein axonemal assembly factor 19 | Not recorded | In 1 condition |
| DNAI2dynein axonemal intermediate chain 2 | Not recorded | In 1 condition |
| DRC4dynein regulatory complex subunit 4 | Not recorded | In 1 condition |
| EIF2AK4eukaryotic translation initiation factor 2 alpha kinase 4 | Not recorded | In 1 condition |
| NKX2-1NK2 homeobox 1 | Not recorded | In 1 condition |
| ODAD3outer dynein arm docking complex subunit 3 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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