Traits

Traits linked to ENG

endoglin

The Human Phenotype Ontology links 85 traits to ENG, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the cardiovascular system

Trait	Kaip dažnai pasireiškia
Cerebral berry aneurysm	Visada
Spider veins	Visada
Telangiectasia of the skin	Visada
Mucosal telangiectasiae	Labai dažnai (80–99%)
Abnormal cardiovascular system physiology	Dažnai (30–79%)
Abnormal circle of Willis morphology	Dažnai (30–79%)
Arteriovenous malformation	Dažnai (30–79%)
Hepatic arteriovenous malformation	Dažnai (30–79%)
High blood pressure	Dažnai (30–79%)
Mini stroke	Dažnai (30–79%)
Narrowing and hardening of arteries	Dažnai (30–79%)
Portal hypertension	Dažnai (30–79%)
Pulmonary arteriovenous malformation	Dažnai (30–79%)
Visceral angiomatosis	Dažnai (30–79%)
Abnormality of the cerebral blood vessels	Kartais (5–29%)
Blood clot in artery of lung	Kartais (5–29%)
Bulge in wall of root of large artery that carries blood away from heart	Kartais (5–29%)
Cardiac failure	Kartais (5–29%)
Cerebral arteriovenous malformation	Kartais (5–29%)
Gastrointestinal arteriovenous malformation	Kartais (5–29%)
Increased blood pressure in blood vessels of lungs	Kartais (5–29%)
Peripheral arteriovenous fistula	Kartais (5–29%)
Retinal telangiectasia	Kartais (5–29%)
Tear in inner wall of large artery that carries blood away from heart	Kartais (5–29%)
Arteriovenous fistulas of celiac and mesenteric vessels	Neužfiksuota
Dilatation of celiac artery	Neužfiksuota
Dilatation of mesenteric artery	Neužfiksuota
Gastrointestinal angiodysplasia	Neužfiksuota
High-output congestive heart failure	Neužfiksuota
Ischemic stroke	Neužfiksuota
Nail bed telangiectasia	Neužfiksuota
Right-to-left shunt	Neužfiksuota
Small dilated blood vessels in fingerpads	Neužfiksuota
Small, enlarged blood vessels near skin	Neužfiksuota
Spinal arteriovenous malformation	Neužfiksuota
Venous varicosities of celiac and mesenteric vessels	Neužfiksuota

Abnormality of blood and blood-forming tissues

Trait	Kaip dažnai pasireiškia
Recurring nosebleed	Visada
Bleeding tendency	Labai dažnai (80–99%)
Bloody nose	Labai dažnai (80–99%)
Low number of red blood cells or hemoglobin	Dažnai (30–79%)
Rectal bleeding	Dažnai (30–79%)
Bleeding in brain	Kartais (5–29%)
Bleeding within the skull	Kartais (5–29%)
Blood clot in vein	Kartais (5–29%)
Gastrointestinal bleeding	Kartais (5–29%)
Subarachnoid hemorrhage	Kartais (5–29%)
Black feces	Neužfiksuota
Increased red blood cells	Neužfiksuota
Pulmonary hemorrhage	Neužfiksuota
Vomiting blood	Neužfiksuota

Abnormality of the digestive system

Trait	Kaip dažnai pasireiškia
Adenomatous colonic polyposis	Dažnai (30–79%)
Rectal polyposis	Dažnai (30–79%)
Enlarged vein in esophagus	Kartais (5–29%)
Growths in inner lining of intestine	Kartais (5–29%)
Liver failure	Kartais (5–29%)
Multiple gastric polyps	Kartais (5–29%)
Scar tissue replaces healthy tissue in the liver	Kartais (5–29%)
Duodenal polyposis	Retai (1–4 %)
Small intestinal polyposis	Retai (1–4 %)

Abnormality of the respiratory system

Trait	Kaip dažnai pasireiškia
Breathing difficulty	Visada
Coughing up blood	Visada
Reduced FEV1/FVC ratio	Kartais (5–29%)
Stiff lung or chest wall causing decreased lung volume	Kartais (5–29%)
Exertional breathlessness	Neužfiksuota
Hemothorax	Neužfiksuota
Low blood oxygen level	Neužfiksuota

Abnormality of head or neck

Trait	Kaip dažnai pasireiškia
Spider veins of mucosa of nose	Labai dažnai (80–99%)
Spider veins of the lip	Labai dažnai (80–99%)
Spider veins of the tongue	Labai dažnai (80–99%)
Small dilated blood vessels near membrane covering front of eye and eyelids	Kartais (5–29%)
Palatal spider veins	Neužfiksuota

Abnormality of the nervous system

Trait	Kaip dažnai pasireiškia
Abnormal shape of brainstem	Dažnai (30–79%)
Epilepsy	Dažnai (30–79%)
Migraine	Dažnai (30–79%)
Weakness of one side of body	Dažnai (30–79%)
Encephalomalacia	Kartais (5–29%)

Abnormality of the eye

Trait	Kaip dažnai pasireiškia
Partial loss of field of vision	Dažnai (30–79%)
Oculomotor nerve palsy	Kartais (5–29%)

Abnormality of the integument

Trait	Kaip dažnai pasireiškia
Anemic pallor	Dažnai (30–79%)
Blue discoloration of the skin	Neužfiksuota

Abnormality of limbs

Trait	Kaip dažnai pasireiškia
Clubbing of fingers and toes	Neužfiksuota

Abnormality of the immune system

Trait	Kaip dažnai pasireiškia
Brain abscess	Neužfiksuota

Constitutional symptom

Trait	Kaip dažnai pasireiškia
Chest pain	Neužfiksuota

Growth abnormality

Trait	Kaip dažnai pasireiškia
Growth delay	Kartais (5–29%)

Laboratory abnormality

Trait	Kaip dažnai pasireiškia
Fluid retention	Kartais (5–29%)

Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.

Iš kur tai žinoma

The Human Phenotype Ontology, release 2026-09-01: the traits linked to ENG and how often each is seen. Find out more at hpo.jax.org.

Vienas testas. Atsakymai visam gyvenimui.

Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites

Įsigyti savo Genome Test