Trait
Chronic pulmonary obstruction
An anomaly that is characterized progressive airflow obstruction that is only partly reversible, inflammation in the airways, and systemic effects or comorbities.
Summary
- Also called
- Chronic obstructive pulmonary disease, COPD
- Body system
- Abnormality of the respiratory system
Reference genomeGRCh38hg38
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Get my Genome Test37 genes linked to Chronic pulmonary obstruction
Changes in these genes cause rare conditions in which Chronic pulmonary obstruction is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| RAC2Rac family small GTPase 2 | Always | In 1 condition |
| SOX17SRY-box transcription factor 17 | Always | In 1 condition |
| CYBAcytochrome b-245 alpha chain | Very often (80–99%) | In 1 condition |
| CYBBcytochrome b-245 beta chain | Very often (80–99%) | In 1 condition |
| CYBC1cytochrome b-245 chaperone 1 | Very often (80–99%) | In 1 condition |
| NCF1neutrophil cytosolic factor 1 | Very often (80–99%) | In 1 condition |
| NCF2neutrophil cytosolic factor 2 | Very often (80–99%) | In 1 condition |
| NCF4neutrophil cytosolic factor 4 | Very often (80–99%) | In 1 condition |
| WASWASP actin nucleation promoting factor | Very often (80–99%) | In 1 condition |
| CARMIL2capping protein regulator and myosin 1 linker 2 | Often (30–79%) | In 1 condition |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Often (30–79%) | In 1 condition |
| HLA-DPA1major histocompatibility complex, class II, DP alpha 1 | Often (30–79%) | In 1 condition |
| HLA-DPB1major histocompatibility complex, class II, DP beta 1 | Often (30–79%) | In 1 condition |
| PRTN3proteinase 3 | Often (30–79%) | In 1 condition |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Often (30–79%) | In 1 condition |
| ALMS1ALMS1 centrosome and basal body associated protein | Sometimes (5–29%) | In 1 condition |
| ARVCFARVCF delta catenin family member | Sometimes (5–29%) | In 1 condition |
| BLMBLM RecQ like helicase | Sometimes (5–29%) | In 1 condition |
| COMTcatechol-O-methyltransferase | Sometimes (5–29%) | In 1 condition |
| DNAAF4dynein axonemal assembly factor 4 | Sometimes (5–29%) | In 1 condition |
| GLAgalactosidase alpha | Sometimes (5–29%) | In 1 condition |
| GP1BBglycoprotein Ib platelet subunit beta | Sometimes (5–29%) | In 1 condition |
| HIRAhistone cell cycle regulator | Sometimes (5–29%) | In 1 condition |
| JMJD1Cjumonji domain containing 1C | Sometimes (5–29%) | In 1 condition |
| MPEG1macrophage expressed 1 | Sometimes (5–29%) | In 1 condition |
| NFKB1nuclear factor kappa B subunit 1 | Sometimes (5–29%) | In 1 condition |
| RREB1ras responsive element binding protein 1 | Sometimes (5–29%) | In 1 condition |
| RSPH1radial spoke head component 1 | Sometimes (5–29%) | In 1 condition |
| RSPH3radial spoke head 3 | Sometimes (5–29%) | In 1 condition |
| RSPH9radial spoke head component 9 | Sometimes (5–29%) | In 1 condition |
| SEC24CSEC24 homolog C, COPII component | Sometimes (5–29%) | In 1 condition |
| SERPINA1serpin family A member 1 | Sometimes (5–29%) | In 2 conditions |
| TBX1T-box transcription factor 1 | Sometimes (5–29%) | In 2 conditions |
| THSD4thrombospondin type 1 domain containing 4 | Sometimes (5–29%) | In 1 condition |
| UFD1ubiquitin recognition factor in ER associated degradation 1 | Sometimes (5–29%) | In 1 condition |
| HMOX1heme oxygenase 1 | Not recorded | In 1 condition |
| MCIDASmulticiliate differentiation and DNA synthesis associated cell cycle protein | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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