Trait
Angina pectoris
Paroxysmal chest pain that occurs with exertion or stress and is related to myocardial ischemia.
Summary
- Body system
- Abnormality of the cardiovascular system
Reference genomeGRCh38hg38
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Get my Genome Test36 genes linked to Angina pectoris
Changes in these genes cause rare conditions in which Angina pectoris is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| JAK2Janus kinase 2 | Very often (80–99%) | In 1 condition |
| ABCA1ATP binding cassette subfamily A member 1 | Often (30–79%) | In 1 condition |
| ABCG5ATP binding cassette subfamily G member 5 | Often (30–79%) | In 1 condition |
| ABCG8ATP binding cassette subfamily G member 8 | Often (30–79%) | In 1 condition |
| APOA1apolipoprotein A1 | Often (30–79%) | In 1 condition |
| APOBapolipoprotein B | Often (30–79%) | In 1 condition |
| ELNelastin | Often (30–79%) | In 1 condition |
| JPH2junctophilin 2 | Often (30–79%) | In 1 condition |
| LDLRlow density lipoprotein receptor | Often (30–79%) | In 1 condition |
| LDLRAP1low density lipoprotein receptor adaptor protein 1 | Often (30–79%) | In 1 condition |
| LIPClipase C, hepatic type | Often (30–79%) | In 2 conditions |
| PCSK9proprotein convertase subtilisin/kexin type 9 | Often (30–79%) | In 1 condition |
| PNPLA2patatin like domain 2, triacylglycerol lipase | Often (30–79%) | In 1 condition |
| TNNC1troponin C1, slow skeletal and cardiac type | Often (30–79%) | In 1 condition |
| TNNT2troponin T2, cardiac type | Often (30–79%) | In 1 condition |
| ABCC6ATP binding cassette subfamily C member 6 | Sometimes (5–29%) | In 3 conditions |
| ACTC1actin alpha cardiac muscle 1 | Sometimes (5–29%) | In 1 condition |
| APOEapolipoprotein E | Sometimes (5–29%) | In 1 condition |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Sometimes (5–29%) | In 1 condition |
| ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 1 | Sometimes (5–29%) | In 1 condition |
| GLAgalactosidase alpha | Sometimes (5–29%) | In 2 conditions |
| HLA-DPA1major histocompatibility complex, class II, DP alpha 1 | Sometimes (5–29%) | In 1 condition |
| HLA-DPB1major histocompatibility complex, class II, DP beta 1 | Sometimes (5–29%) | In 1 condition |
| IDUAalpha-L-iduronidase | Sometimes (5–29%) | In 1 condition |
| LCATlecithin-cholesterol acyltransferase | Sometimes (5–29%) | In 1 condition |
| PRTN3proteinase 3 | Sometimes (5–29%) | In 1 condition |
| PTENphosphatase and tensin homolog | Sometimes (5–29%) | In 1 condition |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Sometimes (5–29%) | In 1 condition |
| TRIM63tripartite motif containing 63 | Sometimes (5–29%) | In 1 condition |
| TTRtransthyretin | Sometimes (5–29%) | In 1 condition |
| LMNAlamin A/C | Rarely (1–4%) | In 2 conditions |
| PMM2phosphomannomutase 2 | Rarely (1–4%) | In 1 condition |
| ZMPSTE24zinc metallopeptidase STE24 | Rarely (1–4%) | In 1 condition |
| CYP27A1cytochrome P450 family 27 subfamily A member 1 | Not recorded | In 1 condition |
| XYLT1xylosyltransferase 1 | Not recorded | In 1 condition |
| XYLT2xylosyltransferase 2 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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