Trait
Blood clot in vein
Clinical name: Venous thrombosis
Formation of a blood clot (thrombus) inside a vein, causing the obstruction of blood flow.
Summary
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test50 genes linked to Blood clot in vein
Changes in these genes cause rare conditions in which Blood clot in vein is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CALRcalreticulin | Very often (80–99%) | In 2 conditions |
| EPORerythropoietin receptor | Very often (80–99%) | In 1 condition |
| IDH1isocitrate dehydrogenase (NADP(+)) 1 | Very often (80–99%) | In 2 conditions |
| IDH2isocitrate dehydrogenase (NADP(+)) 2 | Very often (80–99%) | In 2 conditions |
| JAK2Janus kinase 2 | Very often (80–99%) | In 4 conditions |
| MPLMPL proto-oncogene, thrombopoietin receptor | Very often (80–99%) | In 3 conditions |
| SH2B3SH2B adaptor protein 3 | Very often (80–99%) | In 1 condition |
| TET2tet methylcytosine dioxygenase 2 | Very often (80–99%) | In 2 conditions |
| THPOthrombopoietin | Very often (80–99%) | In 1 condition |
| TP53tumor protein p53 | Very often (80–99%) | In 1 condition |
| AGGF1angiogenic factor with G-patch and FHA domains 1 | Often (30–79%) | In 1 condition |
| C4Acomplement C4A (Chido/Rodgers blood group) | Often (30–79%) | In 1 condition |
| CBScystathionine beta-synthase | Often (30–79%) | In 1 condition |
| CCR1C-C motif chemokine receptor 1 | Often (30–79%) | In 1 condition |
| ERAP1endoplasmic reticulum aminopeptidase 1 | Often (30–79%) | In 1 condition |
| FASFas cell surface death receptor | Often (30–79%) | In 1 condition |
| FGAfibrinogen alpha chain | Often (30–79%) | In 1 condition |
| FGBfibrinogen beta chain | Often (30–79%) | In 1 condition |
| FGGfibrinogen gamma chain | Often (30–79%) | In 1 condition |
| HLA-Bmajor histocompatibility complex, class I, B | Often (30–79%) | In 1 condition |
| IFNGR1interferon gamma receptor 1 | Often (30–79%) | In 1 condition |
| IL10interleukin 10 | Often (30–79%) | In 1 condition |
| IL12Ainterleukin 12A | Often (30–79%) | In 1 condition |
| IL12A-AS1IL12A antisense RNA 1 | Often (30–79%) | In 1 condition |
| IL23Rinterleukin 23 receptor | Often (30–79%) | In 1 condition |
| KLRC4killer cell lectin like receptor C4 | Often (30–79%) | In 1 condition |
| MEFVMEFV innate immunity regulator, pyrin | Often (30–79%) | In 1 condition |
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Often (30–79%) | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Often (30–79%) | In 1 condition |
| PROCprotein C, inactivator of coagulation factors Va and VIIIa | Often (30–79%) | In 1 condition |
| SAA1serum amyloid A1 | Often (30–79%) | In 1 condition |
| STAT4signal transducer and activator of transcription 4 | Often (30–79%) | In 1 condition |
| TLR4toll like receptor 4 | Often (30–79%) | In 1 condition |
| UBAC2UBA domain containing 2 | Often (30–79%) | In 1 condition |
| ACVRL1activin A receptor like type 1 | Sometimes (5–29%) | In 1 condition |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Sometimes (5–29%) | In 1 condition |
| ENGendoglin | Sometimes (5–29%) | In 1 condition |
| GDF2growth differentiation factor 2 | Sometimes (5–29%) | In 1 condition |
| GNAQG protein subunit alpha q | Sometimes (5–29%) | In 2 conditions |
| HBBhemoglobin subunit beta | Sometimes (5–29%) | In 2 conditions |
Show 10 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| HLA-DPA1major histocompatibility complex, class II, DP alpha 1 | Sometimes (5–29%) | In 1 condition |
| HLA-DPB1major histocompatibility complex, class II, DP beta 1 | Sometimes (5–29%) | In 1 condition |
| KIF11kinesin family member 11 | Sometimes (5–29%) | In 1 condition |
| PRTN3proteinase 3 | Sometimes (5–29%) | In 1 condition |
| PTH1Rparathyroid hormone 1 receptor | Sometimes (5–29%) | In 1 condition |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Sometimes (5–29%) | In 1 condition |
| SMAD4SMAD family member 4 | Sometimes (5–29%) | In 1 condition |
| F2coagulation factor II, thrombin | Not recorded | In 1 condition |
| PDGFRAplatelet derived growth factor receptor alpha | Not recorded | In 1 condition |
| PIGMphosphatidylinositol glycan anchor biosynthesis class M | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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