Trait
Swelling or irritation of membrane around heart
Clinical name: Pericarditis
Inflammation of the sac-like covering around the heart (pericardium).
Summary
Reference genomeGRCh38hg38
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Get my Genome Test42 genes linked to Swelling or irritation of membrane around heart
Changes in these genes cause rare conditions in which Swelling or irritation of membrane around heart is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| DOCK11dedicator of cytokinesis 11 | Always | In 1 condition |
| LCKLCK proto-oncogene, Src family tyrosine kinase | Always | In 1 condition |
| TNFRSF1ATNF receptor superfamily member 1A | Very often (80–99%) | In 1 condition |
| MAFMAF bZIP transcription factor | Often (30–79%) | In 2 conditions |
| C4Acomplement C4A (Chido/Rodgers blood group) | Sometimes (5–29%) | In 1 condition |
| CCR1C-C motif chemokine receptor 1 | Sometimes (5–29%) | In 1 condition |
| CD4CD4 molecule | Sometimes (5–29%) | In 1 condition |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Sometimes (5–29%) | In 1 condition |
| ERAP1endoplasmic reticulum aminopeptidase 1 | Sometimes (5–29%) | In 1 condition |
| FASFas cell surface death receptor | Sometimes (5–29%) | In 1 condition |
| HBA1hemoglobin subunit alpha 1 | Sometimes (5–29%) | In 1 condition |
| HBA2hemoglobin subunit alpha 2 | Sometimes (5–29%) | In 1 condition |
| HLA-Bmajor histocompatibility complex, class I, B | Sometimes (5–29%) | In 3 conditions |
| HLA-DPA1major histocompatibility complex, class II, DP alpha 1 | Sometimes (5–29%) | In 1 condition |
| HLA-DPB1major histocompatibility complex, class II, DP beta 1 | Sometimes (5–29%) | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Sometimes (5–29%) | In 2 conditions |
| IFNGR1interferon gamma receptor 1 | Sometimes (5–29%) | In 1 condition |
| IL10interleukin 10 | Sometimes (5–29%) | In 1 condition |
| IL12Ainterleukin 12A | Sometimes (5–29%) | In 1 condition |
| IL12A-AS1IL12A antisense RNA 1 | Sometimes (5–29%) | In 1 condition |
| IL23Rinterleukin 23 receptor | Sometimes (5–29%) | In 1 condition |
| IL6interleukin 6 | Sometimes (5–29%) | In 1 condition |
| IRF4interferon regulatory factor 4 | Sometimes (5–29%) | In 1 condition |
| KLRC4killer cell lectin like receptor C4 | Sometimes (5–29%) | In 1 condition |
| LACC1laccase domain multifunctional purine nucleosidase 1 | Sometimes (5–29%) | In 1 condition |
| MEFVMEFV innate immunity regulator, pyrin | Sometimes (5–29%) | In 3 conditions |
| MIFmacrophage migration inhibitory factor | Sometimes (5–29%) | In 1 condition |
| NOD2nucleotide binding oligomerization domain containing 2 | Sometimes (5–29%) | In 3 conditions |
| P4HA2prolyl 4-hydroxylase subunit alpha 2 | Sometimes (5–29%) | In 1 condition |
| PMM2phosphomannomutase 2 | Sometimes (5–29%) | In 2 conditions |
| PRG4proteoglycan 4 | Sometimes (5–29%) | In 1 condition |
| PRTN3proteinase 3 | Sometimes (5–29%) | In 1 condition |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Sometimes (5–29%) | In 2 conditions |
| RNU7-1RNA, U7 small nuclear 1 | Sometimes (5–29%) | In 1 condition |
| STAT4signal transducer and activator of transcription 4 | Sometimes (5–29%) | In 1 condition |
| TLR4toll like receptor 4 | Sometimes (5–29%) | In 1 condition |
| UBAC2UBA domain containing 2 | Sometimes (5–29%) | In 1 condition |
| NF1neurofibromin 1 | Rarely (1–4%) | In 1 condition |
| DNASE1deoxyribonuclease 1 | Not recorded | In 1 condition |
| FCGR2AFc gamma receptor IIa | Not recorded | In 1 condition |
Show 2 more genes
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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