Trait

Recurrent bleeding into lungs

Clinical name: Recurrent intrapulmonary hemorrhage

A recurrent hemorrhage occurring within the lung.

HPO HP:0006535

Also called: Recurrent intrapulmonary haemorrhage, Recurrent pulmonary haemorrhage, Recurrent pulmonary hemorrhage
Body system: Abnormality of blood and blood-forming tissues Abnormality of the cardiovascular system Abnormality of the respiratory system

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7 genes linked to Recurrent bleeding into lungs

Changes in these genes cause rare conditions in which Recurrent bleeding into lungs is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
CTLA4cytotoxic T-lymphocyte associated protein 4	Often (30–79%)	In 1 condition
HLA-DPA1major histocompatibility complex, class II, DP alpha 1	Often (30–79%)	In 1 condition
HLA-DPB1major histocompatibility complex, class II, DP beta 1	Often (30–79%)	In 1 condition
PRTN3proteinase 3	Often (30–79%)	In 1 condition
PTPN22protein tyrosine phosphatase non-receptor type 22	Often (30–79%)	In 1 condition
WASWASP actin nucleation promoting factor	Sometimes (5–29%)	In 1 condition
COL3A1collagen type III alpha 1 chain	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Pulmonary hemorrhage

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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