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Gene

TMEM259

transmembrane protein 259

Summary

Cytogenetic location
19p13.3
Coordinates
Chromosome 19: 1,009,653–1,021,123 (GRCh38)
Exons
11 exons across 11.5 kb
Protein
620 amino acids
Also known as
MGC4022, ASBABP1, MBRL
Previous symbols
C19orf6
MANE Select transcript
ENST00000356663.8NM_001033026.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TMEM259 yet. The test sequences your whole genome, so your data includes it all the same.

How TMEM259 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 19, with a bracket where TMEM259 sits. TMEM259 and 49 genes near it on chromosome 19, from 515,388 to 1,515,387.Chromosome 1919p13.3p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.430.6 Mb0.8 Mb1 Mb1.2 Mb1.4 MbTPGS1: 507,488–520,846, forward strandTPGS1CDC34: 531,435–542,092, forward strandCDC34GZMM: 544,034–549,924, forward strandGZMMBSG: 571,277–583,498, forward strandBSGHCN2: 589,881–617,159, forward strandHCN2POLRMT: 617,168–633,619, reverse strandPOLRMTFGF22: 639,879–644,373, forward strandFGF22RNF126: 647,526–663,336, reverse strandRNF126FSTL3: 676,366–683,793, forward strandFSTL3PRSS57: 685,546–695,498, reverse strandPRSS57PALM: 708,906–748,329, forward strandPALMMISP: 748,404–764,363, forward strandMISPPTBP1: 797,075–812,327, forward strandPLPPR3: 810,908–822,619, reverse strandAZU1: 825,097–832,018, forward strandAZU1PRTN3: 840,999–848,255, forward strandPRTN3ELANE: 850,951–856,247, forward strandELANECFD: 859,426–869,492, forward strandCFDMED16: 867,630–893,222, reverse strandMED16R3HDM4: 896,503–913,245, reverse strandR3HDM4KISS1R: 917,287–921,005, forward strandKISS1RARID3A: 924,528–975,939, forward strandARID3AWDR18: 984,248–998,438, forward strandWDR18GRIN3B: 1,000,419–1,009,732, forward strandGRIN3BTMEM259: 1,009,653–1,021,123, reverse strandTMEM259CNN2: 1,026,270–1,039,077, forward strandCNN2ABCA7: 1,039,997–1,065,572, forward strandABCA7ARHGAP45: 1,065,923–1,087,829, forward strandARHGAP45POLR2E: 1,085,104–1,095,486, reverse strandPOLR2EGPX4: 1,103,982–1,106,791, forward strandGPX4SBNO2: 1,107,634–1,174,295, reverse strandSBNO2STK11: 1,177,558–1,228,431, forward strandSTK11CBARP: 1,228,282–1,239,465, reverse strandCBARPATP5F1D: 1,241,734–1,244,828, forward strandATP5F1DMIDN: 1,248,316–1,259,145, forward strandMIDNCIRBP: 1,259,384–1,274,880, forward strandCIRBPFAM174C: 1,275,509–1,279,244, forward strandFAM174C: 1,276,021–1,279,244, forward strandEFNA2: 1,285,873–1,301,431, forward strandPWWP3A: 1,354,293–1,378,434, forward strandPWWP3ANDUFS7: 1,383,527–1,395,590, forward strandNDUFS7GAMT: 1,397,026–1,401,731, reverse strandGAMTDAZAP1: 1,407,533–1,435,687, forward strandDAZAP1RPS15: 1,438,149–1,440,508, forward strandRPS15APC2: 1,446,302–1,473,244, forward strandAPC2C19orf25: 1,461,143–1,479,565, reverse strandC19orf25PCSK4: 1,481,428–1,490,752, reverse strandPCSK4REEP6: 1,491,016–1,497,928, forward strandREEP6ADAMTSL5: 1,503,045–1,513,604, reverse strandPLK5: 1,507,978–1,536,046, forward strandDiagram of TMEM259: 11 exons on the reverse strand of chromosome 19Exon 11: 1,009,653–1,010,895, 1,243 basesExon 10: 1,011,096–1,011,195, 100 basesExon 9: 1,011,367–1,011,499, 133 basesExon 8: 1,011,580–1,011,663, 84 basesExon 7: 1,011,741–1,011,798, 58 basesExon 6: 1,011,892–1,011,992, 101 basesExon 5: 1,012,066–1,012,188, 123 basesExon 4: 1,012,463–1,012,573, 111 basesExon 3: 1,013,241–1,013,340, 100 basesExon 2: 1,014,192–1,014,473, 282 basesExon 1: 1,020,772–1,021,123, 352 bases1110864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.7 kb of the gene's 11.5 kb; 1,863 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TMEM259 gene: transmembrane protein 259. Retrieved 17 October 2026, from https://dantelabs.com/genes/tmem259

Vancouver

Dante Labs. TMEM259 gene: transmembrane protein 259 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tmem259

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