Gene
ARHGAP19
Rho GTPase activating protein 19
- HGNC 23724(opens in a new tab)
- Ensembl gene ENSG00000213390(opens in a new tab)
- NCBI Gene 84986(opens in a new tab)
Summary
- Cytogenetic location
- 10q24.1
- Coordinates
- Chromosome 10: 97,222,179–97,292,637 (GRCh38)
- Exons
- 12 exons across 70.5 kb
- Protein
- 494 amino acids
- Also known as
- FLJ00194, MGC14258
- MANE Select transcript
- ENST00000358531.9NM_032900.6
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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No Genome Test report reads ARHGAP19 yet. The test sequences your whole genome, so your data includes it all the same.
How ARHGAP19 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 5.4 kb of the gene's 70.5 kb; 1,485 of those bases code for the protein.
How a genome test reads ARHGAP19
1
position in ARHGAP19 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 70.5 kb of ARHGAP19, introns included, not only the 5.4 kb of exons.
Traits linked to ARHGAP19
The Human Phenotype Ontology lists these as features of the rare conditions ARHGAP19 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Abnormal gait
- Decreased motor nerve conduction velocity
- Demyelinating motor neuropathy
- Falls
- Fluid-filled cyst in spinal cord
- Impaired distal proprioception
- Impaired distal vibration sensation
- Impaired temperature sensation
Show 12 more traits
- Impaired toe-walking ability
- Mixed demyelinating and axonal polyneuropathy
- Motor axonal neuropathy
- Motor polyneuropathy
- Nerve damage causing decreased feeling and movement
- Peripheral axonal neuropathy
- Peripheral nerve disease
- High stepping
- Babinski sign
- Decreased touch sensation in extremities
- Impaired vibratory sensation
- Waddling gait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). ARHGAP19 gene: Rho GTPase activating protein 19. Retrieved 17 October 2026, from https://dantelabs.com/genes/arhgap19
Dante Labs. ARHGAP19 gene: Rho GTPase activating protein 19 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/arhgap19
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