Trait
Floppy windpipe
Clinical name: Tracheomalacia
Summary
- Body system
- Abnormality of the respiratory system
Reference genomeGRCh38hg38
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Get my Genome Test43 genes linked to Floppy windpipe
Changes in these genes cause rare conditions in which Floppy windpipe is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ESAMendothelial cell adhesion molecule | Always | In 1 condition |
| PRRX1paired related homeobox 1 | Always | In 1 condition |
| PTBP1polypyrimidine tract binding protein 1 | Always | In 1 condition |
| RNU5B-1RNA, U5B small nuclear 1 | Always | In 1 condition |
| FGFR2fibroblast growth factor receptor 2 | Very often (80–99%) | In 2 conditions |
| SOX9SRY-box transcription factor 9 | Very often (80–99%) | In 3 conditions |
| AFF4ALF transcription elongation factor 4 | Often (30–79%) | In 2 conditions |
| LTBP4latent transforming growth factor beta binding protein 4 | Often (30–79%) | In 1 condition |
| MYCNMYCN proto-oncogene, bHLH transcription factor | Often (30–79%) | In 1 condition |
| MYRFmyelin regulatory factor | Often (30–79%) | In 1 condition |
| POLGDNA polymerase gamma, catalytic subunit | Often (30–79%) | In 1 condition |
| RAP1BRAP1B, member of RAS oncogene family | Often (30–79%) | In 1 condition |
| RBSNrabenosyn, RAB effector | Often (30–79%) | In 1 condition |
| SNRPBsmall nuclear ribonucleoprotein polypeptides B and B1 | Often (30–79%) | In 1 condition |
| ADAMTSL2ADAMTS like 2 | Sometimes (5–29%) | In 1 condition |
| AHDC1AT-hook DNA binding motif containing 1 | Sometimes (5–29%) | In 2 conditions |
| B3GALT6beta-1,3-galactosyltransferase 6 | Sometimes (5–29%) | In 1 condition |
| CHD6chromodomain helicase DNA binding protein 6 | Sometimes (5–29%) | In 1 condition |
| DCHS1dachsous cadherin-related 1 | Sometimes (5–29%) | In 2 conditions |
| ERFETS2 repressor factor | Sometimes (5–29%) | In 1 condition |
| FAT4FAT atypical cadherin 4 | Sometimes (5–29%) | In 2 conditions |
| FBN1fibrillin 1 | Sometimes (5–29%) | In 1 condition |
| HDAC4histone deacetylase 4 | Sometimes (5–29%) | In 1 condition |
| LTBP3latent transforming growth factor beta binding protein 3 | Sometimes (5–29%) | In 1 condition |
| PAX3paired box 3 | Sometimes (5–29%) | In 1 condition |
| RALGAPA1Ral GTPase activating protein catalytic subunit alpha 1 | Sometimes (5–29%) | In 1 condition |
| SETD2SET domain containing 2, histone lysine methyltransferase | Sometimes (5–29%) | In 1 condition |
| USP9Xubiquitin specific peptidase 9 X-linked | Sometimes (5–29%) | In 1 condition |
| WDR26WD repeat domain 26 | Sometimes (5–29%) | In 1 condition |
| ZNF699zinc finger protein 699 | Sometimes (5–29%) | In 1 condition |
| EHMT1euchromatic histone lysine methyltransferase 1 | Rarely (1–4%) | In 1 condition |
| KMT2Clysine methyltransferase 2C | Rarely (1–4%) | In 1 condition |
| MID1midline 1 | Rarely (1–4%) | In 1 condition |
| AMER1APC membrane recruitment protein 1 | Not recorded | In 1 condition |
| BMPERBMP binding endothelial regulator | Not recorded | In 1 condition |
| COL2A1collagen type II alpha 1 chain | Not recorded | In 1 condition |
| FLNBfilamin B | Not recorded | In 1 condition |
| HRASHRas proto-oncogene, GTPase | Not recorded | In 1 condition |
| ORC4origin recognition complex subunit 4 | Not recorded | In 1 condition |
| ORC6origin recognition complex subunit 6 | Not recorded | In 1 condition |
Show 3 more genes
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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