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Gene

MYRF

myelin regulatory factor

Summary

Cytogenetic location
11q12.2
Coordinates
Chromosome 11: 61,752,636–61,788,518 (GRCh38)
Exons
27 exons across 35.9 kb
Protein
1,151 amino acids
Also known as
Ndt80, pqn-47, MRF
Previous symbols
C11orf9
MANE Select transcript
ENST00000278836.10NM_001127392.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Trait report that reads MYRF

How MYRF is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 11, with a bracket where MYRF sits. MYRF and 26 genes near it on chromosome 11, from 61,270,577 to 62,270,576.Chromosome 1111q12.2p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2561.4 Mb61.6 Mb61.8 Mb62 Mb62.2 MbVWCE: 61,255,672–61,295,553, reverse strandVWCEDDB1: 61,299,447–61,342,596, reverse strandDDB1TKFC: 61,333,205–61,354,339, forward strandTKFCCYB561A3: 61,348,453–61,362,343, reverse strandCYB561A3TMEM138: 61,361,964–61,377,890, forward strandTMEM138TMEM216: 61,392,393–61,400,408, forward strandTMEM216CPSF7: 61,402,641–61,430,105, reverse strandCPSF7: 61,429,220–61,485,822, forward strandSDHAF2: 61,430,032–61,473,614, forward strandSDHAF2SAXO4: 61,481,120–61,490,931, forward strandSAXO4LRRC10B: 61,508,749–61,511,018, forward strandLRRC10BSYT7: 61,513,714–61,581,201, reverse strandSYT7DAGLA: 61,680,151–61,747,003, forward strandDAGLAMYRF: 61,752,636–61,788,518, forward strandMYRFTMEM258: 61,768,455–61,792,802, reverse strandTMEM258FEN1: 61,792,725–61,797,238, forward strandFEN1FADS2: 61,792,980–61,867,354, forward strandFADS1: 61,799,624–61,829,318, reverse strandFADS1FADS3: 61,873,515–61,892,136, reverse strandFADS3RAB3IL1: 61,897,232–61,920,289, reverse strandRAB3IL1BEST1: 61,949,808–61,965,515, forward strandBEST1FTH1: 61,959,718–61,967,640, reverse strandFTH1INCENP: 62,123,985–62,155,474, forward strandINCENPSCGB1D1: 62,190,216–62,193,539, forward strandSCGB1D1SCGB2A1: 62,208,666–62,213,943, forward strandSCGB2A1SCGB1D2: 62,242,210–62,244,812, forward strandSCGB1D2SCGB2A2: 62,270,158–62,273,160, forward strandSCGB2A2Diagram of MYRF: 27 exons on the forward strand of chromosome 11Exon 4: 1 known disease-causing siteExon 5: 2 known disease-causing sitesExon 6: 3 known disease-causing sitesExon 7: 1 known disease-causing siteExon 8: 2 known disease-causing sitesExon 9: 1 known disease-causing siteExon 10: 1 known disease-causing siteExon 11: 2 known disease-causing sitesExon 12: 2 known disease-causing sitesExon 15: 2 known disease-causing sitesExon 19: 1 known disease-causing siteExon 20: 2 known disease-causing sitesExon 22: 2 known disease-causing sitesExon 23: 1 known disease-causing siteExon 25: 1 known disease-causing siteExon 1: 61,752,636–61,752,790, 155 basesExon 2: 61,765,625–61,765,712, 88 basesExon 3: 61,765,958–61,766,221, 264 basesExon 4: 61,769,260–61,769,321, 62 basesExon 5: 61,770,246–61,770,525, 280 basesExon 6: 61,771,500–61,771,750, 251 basesExon 7: 61,771,829–61,771,952, 124 basesExon 8: 61,773,967–61,774,162, 196 basesExon 9: 61,776,056–61,776,132, 77 basesExon 10: 61,776,322–61,776,432, 111 basesExon 11: 61,776,787–61,776,877, 91 basesExon 12: 61,777,264–61,777,464, 201 basesExon 13: 61,777,734–61,777,845, 112 basesExon 14: 61,778,380–61,778,489, 110 basesExon 15: 61,779,263–61,779,423, 161 basesExon 16: 61,779,498–61,779,570, 73 basesExon 17: 61,779,842–61,779,930, 89 basesExon 18: 61,780,222–61,780,290, 69 basesExon 19: 61,780,712–61,780,792, 81 basesExon 20: 61,780,960–61,781,045, 86 basesExon 21: 61,781,138–61,781,329, 192 basesExon 22: 61,781,573–61,781,824, 252 basesExon 23: 61,783,498–61,783,600, 103 basesExon 24: 61,783,851–61,783,925, 75 basesExon 25: 61,784,280–61,784,385, 106 basesExon 26: 61,785,800–61,785,874, 75 basesExon 27: 61,786,063–61,788,518, 2,456 bases1510152025275′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.9 kb of the gene's 35.9 kb; 3,456 of those bases code for the protein.

How a genome test reads MYRF

28

positions in MYRF where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 35.9 kb of MYRF, introns included, not only the 5.9 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). MYRF gene: myelin regulatory factor. Retrieved 17 October 2026, from https://dantelabs.com/genes/myrf

Vancouver

Dante Labs. MYRF gene: myelin regulatory factor [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/myrf

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