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Gene

ESAM

endothelial cell adhesion molecule

Summary

Cytogenetic location
11q24.2
Coordinates
Chromosome 11: 124,753,126–124,762,290 (GRCh38)
Exons
7 exons across 9.2 kb
Protein
390 amino acids
Also known as
W117m
MANE Select transcript
ENST00000278927.10NM_138961.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ESAM yet. The test sequences your whole genome, so your data includes it all the same.

How ESAM is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 11, with a bracket where ESAM sits. ESAM and 24 genes near it on chromosome 11, from 124,257,708 to 125,257,707.Chromosome 1111q24.2p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q25124.4 Mb124.6 Mb124.8 Mb125 Mb125.2 MbOR8G5: 124,256,376–124,266,224, forward strandOR8G5OR8D1: 124,302,831–124,315,099, reverse strandOR8D1OR8D2: 124,319,262–124,320,197, reverse strandOR8D2OR8B2: 124,382,394–124,384,499, reverse strandOR8B2OR8B3: 124,395,534–124,399,024, reverse strandOR8B3OR8B4: 124,423,942–124,424,871, reverse strandOR8B4OR8B8: 124,437,445–124,445,696, reverse strandOR8B8OR8B12: 124,539,635–124,545,333, reverse strandOR8B12OR8A1: 124,566,660–124,582,942, forward strandOR8A1PANX3: 124,611,428–124,620,356, forward strandPANX3FYRD1: 124,622,792–124,648,640, forward strandFYRD1SIAE: 124,633,113–124,695,707, reverse strandSIAESPA17: 124,673,327–124,698,312, forward strandSPA17NRGN: 124,739,939–124,749,342, forward strandNRGNVSIG2: 124,747,472–124,752,274, reverse strandVSIG2ESAM: 124,753,126–124,762,290, reverse strandESAMMSANTD2: 124,764,684–124,800,706, reverse strandMSANTD2ROBO3: 124,865,413–124,881,471, forward strandROBO3ROBO4: 124,883,666–124,898,500, reverse strandROBO4HEPACAM: 124,919,205–124,936,431, reverse strandHEPACAMHEPN1: 124,919,250–124,920,677, forward strandHEPN1CCDC15: 124,954,056–125,041,649, forward strandCCDC15SLC37A2: 125,063,067–125,090,516, forward strandSLC37A2TMEM218: 125,094,379–125,111,870, reverse strandTMEM218PKNOX2: 125,164,537–125,434,287, forward strandPKNOX2Diagram of ESAM: 7 exons on the reverse strand of chromosome 11Exon 7: 1 known disease-causing siteExon 4: 1 known disease-causing siteExon 7: 124,753,126–124,753,961, 836 basesExon 6: 124,754,214–124,754,340, 127 basesExon 5: 124,754,641–124,754,763, 123 basesExon 4: 124,756,207–124,756,362, 156 basesExon 3: 124,756,541–124,756,742, 202 basesExon 2: 124,758,349–124,758,527, 179 basesExon 1: 124,762,085–124,762,290, 206 bases76543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.8 kb of the gene's 9.2 kb; 1,173 of those bases code for the protein.

How a genome test reads ESAM

4

positions in ESAM where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 9.2 kb of ESAM, introns included, not only the 1.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ESAM gene: endothelial cell adhesion molecule. Retrieved 17 October 2026, from https://dantelabs.com/genes/esam

Vancouver

Dante Labs. ESAM gene: endothelial cell adhesion molecule [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/esam

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