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Gene

ALG13

ALG13 UDP-N-acetylglucosaminyltransferase subunit

Summary

Cytogenetic location
Xq23
Coordinates
Chromosome X: 111,681,170–111,760,649 (GRCh38)
Exons
27 exons across 79.5 kb
Protein
1,137 amino acids
Also known as
MDS031, YGL047W, FLJ23018, TDRD13, CDG1S
Previous symbols
GLT28D1, CXorf45
MANE Select transcript
ENST00000394780.8NM_001099922.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

    • Congenital Disorders of Glycosylation

      • Congenital Disorders of Glycosylation (CDG)

        One of 98 genes linked to it

        A large group of inherited conditions in which sugar chains (glycans) are not correctly built or attached to proteins and lipids, often affecting the brain, liver, blood clotting, growth and many other body systems. Most are autosomal recessive, but some are X-linked or autosomal dominant.

        • 4 GenCC submitters rate it definitive or strong

    • Epilepsy (Full Panel)

      • Epilepsy

        One of 171 genes linked to it

        A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions.

        • ClinGen rates the link definitive
        • 5 GenCC submitters rate it definitive or strong

    How ALG13 is laid out

    • Coding sequence
    • Untranslated region
    • Intron
    • Direction of transcription
    • Known disease-causing sites
    • Stretches short reads find hard
    Chromosome X, with a bracket where ALG13 sits. ALG13 and 7 genes near it on chromosome X, from 111,220,910 to 112,220,909.Chromosome XXq23p22.33p22.32p22.31p22.2p22.13p22.12p22.11p21.3p21.2p21.1p11.4p11.3p11.23p11.22p11.21p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q23q24q25q26.1q26.2q26.3q27.1q27.2q27.3q28111.4 Mb111.6 Mb111.8 Mb112 Mb112.2 MbPAK3: 110,944,285–111,227,361, forward strandPAK3CAPN6: 111,245,099–111,270,550, reverse strandCAPN6DCX: 111,293,779–111,412,429, reverse strandDCXSERTM2: 111,511,645–111,522,473, forward strandSERTM2ALG13: 111,681,170–111,760,649, forward strandALG13TRPC5: 111,768,011–112,082,776, reverse strandTRPC5TRPC5OS: 111,876,051–111,903,990, forward strandTRPC5OSRTL4: 112,082,965–112,458,566, forward strandRTL4Diagram of ALG13: 27 exons on the forward strand of chromosome XExon 2: 2 known disease-causing sitesExon 3: 1 known disease-causing siteExon 1: 111,681,170–111,681,299, 130 basesExon 2: 111,682,132–111,682,294, 163 basesExon 3: 111,684,965–111,685,103, 139 basesExon 4: 111,708,027–111,708,393, 367 basesExon 5: 111,708,965–111,709,048, 84 basesExon 6: 111,711,675–111,711,725, 51 basesExon 7: 111,712,484–111,712,530, 47 basesExon 8: 111,713,225–111,713,297, 73 basesExon 9: 111,717,846–111,717,927, 82 basesExon 10: 111,718,112–111,718,274, 163 basesExon 11: 111,720,095–111,720,170, 76 basesExon 12: 111,721,603–111,721,711, 109 basesExon 13: 111,722,793–111,722,857, 65 basesExon 14: 111,723,798–111,723,898, 101 basesExon 15: 111,724,934–111,725,061, 128 basesExon 16: 111,726,809–111,727,055, 247 basesExon 17: 111,727,332–111,727,445, 114 basesExon 18: 111,727,614–111,727,770, 157 basesExon 19: 111,728,185–111,728,305, 121 basesExon 20: 111,730,395–111,730,427, 33 basesExon 21: 111,730,525–111,730,580, 56 basesExon 22: 111,735,051–111,735,122, 72 basesExon 23: 111,736,714–111,736,879, 166 basesExon 24: 111,744,668–111,744,904, 237 basesExon 25: 111,752,790–111,752,830, 41 basesExon 26: 111,757,588–111,757,762, 175 basesExon 27: 111,759,734–111,760,649, 916 bases1510152025275′3′

    Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

    Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

    Nearby genes from Ensembl release 116, on GRCh38.

    Exons make up 4.1 kb of the gene's 79.5 kb; 3,414 of those bases code for the protein.

    How a genome test reads ALG13

    3

    positions in ALG13 where ClinVar classes a change as pathogenic or likely pathogenic

    None of them falls in a region short reads find hard.

    A whole genome covers all 79.5 kb of ALG13, introns included, not only the 4.1 kb of exons.

    Where this comes from

    • HGNC: the gene's symbol, name, other symbols and location.
    • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
    • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
    • The ACMG secondary findings list, SF v3.2.
    • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
    • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
    • Data release 2026.10.16-c6eea6bf.

    Cite this page

    APA

    Dante Labs. (n.d.). ALG13 gene: ALG13 UDP-N-acetylglucosaminyltransferase subunit. Retrieved 17 October 2026, from https://dantelabs.com/genes/alg13

    Vancouver

    Dante Labs. ALG13 gene: ALG13 UDP-N-acetylglucosaminyltransferase subunit [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/alg13

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