Trait
Difficulty finding words
Clinical name: Aphasia
An acquired language impairment of some or all of the abilities to produce or comprehend speech and to read or write.
Summary
- Also called
- Losing words, Loss of words
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Difficulty finding words, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test95 genes linked to Difficulty finding words
Changes in these genes cause rare conditions in which Difficulty finding words is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ADA2adenosine deaminase 2 | Always | In 2 conditions |
| ATP1A2ATPase Na+/K+ transporting subunit alpha 2 | Always | In 2 conditions |
| CST3cystatin C | Always | In 1 condition |
| GRNgranulin precursor | Always | In 4 conditions |
| HTRA1HtrA serine peptidase 1 | Always | In 1 condition |
| NOTCH3notch receptor 3 | Always | In 2 conditions |
| VCPvalosin containing protein | Always | In 4 conditions |
| ACTBactin beta | Very often (80–99%) | In 1 condition |
| ACTG1actin gamma 1 | Very often (80–99%) | In 1 condition |
| ARVCFARVCF delta catenin family member | Very often (80–99%) | In 1 condition |
| ATRXATRX chromatin remodeler | Very often (80–99%) | In 1 condition |
| CHMP2Bcharged multivesicular body protein 2B | Very often (80–99%) | In 3 conditions |
| CKAP2Lcytoskeleton associated protein 2L | Very often (80–99%) | In 1 condition |
| COMTcatechol-O-methyltransferase | Very often (80–99%) | In 1 condition |
| EHMT1euchromatic histone lysine methyltransferase 1 | Very often (80–99%) | In 1 condition |
| GP1BBglycoprotein Ib platelet subunit beta | Very often (80–99%) | In 1 condition |
| GRIN2Aglutamate ionotropic receptor NMDA type subunit 2A | Very often (80–99%) | In 3 conditions |
| HIRAhistone cell cycle regulator | Very often (80–99%) | In 1 condition |
| JMJD1Cjumonji domain containing 1C | Very often (80–99%) | In 1 condition |
| L1CAML1 cell adhesion molecule | Very often (80–99%) | In 2 conditions |
| MAPTmicrotubule associated protein tau | Very often (80–99%) | In 5 conditions |
| MT-CO1mitochondrially encoded cytochrome c oxidase I | Very often (80–99%) | In 1 condition |
| MT-CO2mitochondrially encoded cytochrome c oxidase II | Very often (80–99%) | In 1 condition |
| MT-CO3mitochondrially encoded cytochrome c oxidase III | Very often (80–99%) | In 1 condition |
| MT-ND1mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 | Very often (80–99%) | In 1 condition |
| MT-ND4mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 | Very often (80–99%) | In 1 condition |
| MT-ND5mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 | Very often (80–99%) | In 1 condition |
| MT-ND6mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 | Very often (80–99%) | In 1 condition |
| MT-TFmitochondrially encoded tRNA-Phe (UUU/C) | Very often (80–99%) | In 1 condition |
| MT-THmitochondrially encoded tRNA-His (CAU/C) | Very often (80–99%) | In 1 condition |
| MT-TL1mitochondrially encoded tRNA-Leu (UUA/G) 1 | Very often (80–99%) | In 1 condition |
| MT-TQmitochondrially encoded tRNA-Gln (CAA/G) | Very often (80–99%) | In 1 condition |
| MT-TS1mitochondrially encoded tRNA-Ser (UCN) 1 | Very often (80–99%) | In 1 condition |
| MT-TS2mitochondrially encoded tRNA-Ser (AGU/C) 2 | Very often (80–99%) | In 1 condition |
| MT-TWmitochondrially encoded tRNA-Trp (UGA/G) | Very often (80–99%) | In 1 condition |
| NSDHLNAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL | Very often (80–99%) | In 1 condition |
| OCRLOCRL inositol polyphosphate-5-phosphatase | Very often (80–99%) | In 1 condition |
| PLECplectin | Very often (80–99%) | In 1 condition |
| PSEN1presenilin 1 | Very often (80–99%) | In 4 conditions |
| RAI1retinoic acid induced 1 | Very often (80–99%) | In 2 conditions |
Show 55 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| RREB1ras responsive element binding protein 1 | Very often (80–99%) | In 1 condition |
| SEC24CSEC24 homolog C, COPII component | Very often (80–99%) | In 1 condition |
| SMARCA2SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2 | Very often (80–99%) | In 1 condition |
| SQSTM1sequestosome 1 | Very often (80–99%) | In 1 condition |
| TBX1T-box transcription factor 1 | Very often (80–99%) | In 1 condition |
| TCF4transcription factor 4 | Very often (80–99%) | In 1 condition |
| TMEM106Btransmembrane protein 106B | Very often (80–99%) | In 3 conditions |
| TREM2triggering receptor expressed on myeloid cells 2 | Very often (80–99%) | In 5 conditions |
| UFD1ubiquitin recognition factor in ER associated degradation 1 | Very often (80–99%) | In 1 condition |
| FGFR1fibroblast growth factor receptor 1 | Often (30–79%) | In 1 condition |
| KRASKRas proto-oncogene, GTPase | Often (30–79%) | In 1 condition |
| LGI1leucine rich glioma inactivated 1 | Often (30–79%) | In 1 condition |
| MICAL1microtubule associated monooxygenase, calponin and LIM domain containing 1 | Often (30–79%) | In 1 condition |
| NDUFA1NADH:ubiquinone oxidoreductase subunit A1 | Often (30–79%) | In 1 condition |
| RELNreelin | Often (30–79%) | In 1 condition |
| STSsteroid sulfatase | Often (30–79%) | In 1 condition |
| TIA1TIA1 cytotoxic granule associated RNA binding protein | Often (30–79%) | In 1 condition |
| UBTFupstream binding transcription factor | Often (30–79%) | In 1 condition |
| AMER1APC membrane recruitment protein 1 | Sometimes (5–29%) | In 1 condition |
| APPamyloid beta precursor protein | Sometimes (5–29%) | In 1 condition |
| CACNA1Acalcium voltage-gated channel subunit alpha1 A | Sometimes (5–29%) | In 2 conditions |
| COX7Bcytochrome c oxidase subunit 7B | Sometimes (5–29%) | In 1 condition |
| CTNNB1catenin beta 1 | Sometimes (5–29%) | In 1 condition |
| DNM1Ldynamin 1L | Sometimes (5–29%) | In 1 condition |
| FASFas cell surface death receptor | Sometimes (5–29%) | In 1 condition |
| HCCSholocytochrome c synthase | Sometimes (5–29%) | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Sometimes (5–29%) | In 1 condition |
| HNRNPA1heterogeneous nuclear ribonucleoprotein A1 | Sometimes (5–29%) | In 1 condition |
| HNRNPA2B1heterogeneous nuclear ribonucleoprotein A2/B1 | Sometimes (5–29%) | In 1 condition |
| KCNC2potassium voltage-gated channel subfamily C member 2 | Sometimes (5–29%) | In 1 condition |
| L2HGDHL-2-hydroxyglutarate dehydrogenase | Sometimes (5–29%) | In 2 conditions |
| NDUFB11NADH:ubiquinone oxidoreductase subunit B11 | Sometimes (5–29%) | In 1 condition |
| NPPAnatriuretic peptide A | Sometimes (5–29%) | In 1 condition |
| POLR1BRNA polymerase I subunit B | Sometimes (5–29%) | In 1 condition |
| POLR1CRNA polymerase I and III subunit C | Sometimes (5–29%) | In 1 condition |
| POLR1DRNA polymerase I and III subunit D | Sometimes (5–29%) | In 1 condition |
| PRRT2proline rich transmembrane protein 2 | Sometimes (5–29%) | In 1 condition |
| PSEN2presenilin 2 | Sometimes (5–29%) | In 1 condition |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Sometimes (5–29%) | In 1 condition |
| SCN1Asodium voltage-gated channel alpha subunit 1 | Sometimes (5–29%) | In 1 condition |
| SCN5Asodium voltage-gated channel alpha subunit 5 | Sometimes (5–29%) | In 1 condition |
| SETBP1SET binding protein 1 | Sometimes (5–29%) | In 1 condition |
| SMARCAL1SNF2 related chromatin remodeling annealing helicase 1 | Sometimes (5–29%) | In 1 condition |
| SORL1sortilin related receptor 1 | Sometimes (5–29%) | In 1 condition |
| TCOF1treacle ribosome biogenesis factor 1 | Sometimes (5–29%) | In 1 condition |
| TOMM40translocase of outer mitochondrial membrane 40 | Sometimes (5–29%) | In 1 condition |
| TREX1three prime repair exonuclease 1 | Sometimes (5–29%) | In 1 condition |
| NF2NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor | Rarely (1–4%) | In 1 condition |
| CFHcomplement factor H | Not recorded | In 1 condition |
| CFHR1complement factor H related 1 | Not recorded | In 1 condition |
| CFHR3complement factor H related 3 | Not recorded | In 1 condition |
| CYLDCYLD lysine 63 deubiquitinase | Not recorded | In 1 condition |
| FLCNfolliculin | Not recorded | In 1 condition |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Not recorded | In 1 condition |
| PRNPprion protein (Kanno blood group) | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks