Gene
MICAL1
microtubule associated monooxygenase, calponin and LIM domain containing 1
- HGNC 20619↗(opens in a new tab)
- Ensembl gene ENSG00000135596↗(opens in a new tab)
- NCBI Gene 64780↗(opens in a new tab)
Summary
- Cytogenetic location
- 6q21
- Coordinates
- Chromosome 6: 109,444,062–109,455,772 (GRCh38)
- Exons
- 25 exons across 11.7 kb
- Protein
- 1,067 amino acids
- Also known as
- MICAL, FLJ11937, DKFZp434B1517, FLJ21739
- Previous symbols
- NICAL
- MANE Select transcript
- ENST00000358807.8NM_022765.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How MICAL1 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 3.4 kb of the gene's 11.7 kb; 3,204 of those bases code for the protein.
Traits linked to MICAL1
The Human Phenotype Ontology lists these as features of the rare conditions MICAL1 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Grand mal seizures
- EEG with focal epileptiform discharges
- Hallucinations of sound
- Seizure affecting one half of brain
- Bilateral tonic-clonic seizure with focal onset
- Difficulty finding words
- Focal autonomic seizure with epigastric sensation/nausea/vomiting/other gastrointestinal phenomena
- Focal aware seizure
Show 22 more traits
- Focal aware sensory seizure with auditory features
- Focal impaired awareness seizure
- Focal sensory seizure with auditory features
- Interictal epileptiform activity
- Abnormal autonomic nervous system physiology
- Deja vu
- Focal automatism seizure
- Focal autonomic seizure
- Focal autonomic seizure with palpitations/tachycardia/bradycardia/asystole
- Focal clonic seizure
- Focal sensory seizure with cephalic sensation
- Focal sensory seizure with vestibular features
- Focal sensory seizure with visual features
- Nocturnal seizures
- Visual hallucinations
- Behavioral abnormality
- Depression
- Generalized-onset seizure
- Impulsivity
- Migraine
- Brain imaging abnormality
- Intellectual disability
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). MICAL1 gene: microtubule associated monooxygenase, calponin and LIM domain containing 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/mical1
Dante Labs. MICAL1 gene: microtubule associated monooxygenase, calponin and LIM domain containing 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/mical1
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