Trait
Central apnea
Apnea resulting from depression of the respiratory centers in the medulla oblongata. There is a lack of respiratory effort rather than obstruction of airflow.
Summary
- Also called
- Central apnoea
- Body system
- Abnormality of the respiratory system
Reference genomeGRCh38hg38
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Get my Genome Test45 genes linked to Central apnea
Changes in these genes cause rare conditions in which Central apnea is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| MED16mediator complex subunit 16 | Always | In 1 condition |
| PSAPprosaposin | Always | In 1 condition |
| RNU4-2RNA, U4 small nuclear 2 | Always | In 1 condition |
| TECPR2tectonin beta-propeller repeat containing 2 | Always | In 2 conditions |
| UGGT1UDP-glucose glycoprotein glucosyltransferase 1 | Always | In 1 condition |
| BICD2BICD cargo adaptor 2 | Often (30–79%) | In 1 condition |
| CDONcell adhesion associated, oncogene regulated | Often (30–79%) | In 4 conditions |
| CRIPTOcripto, EGF-CFC family member | Often (30–79%) | In 4 conditions |
| DISP1dispatched RND transporter family member 1 | Often (30–79%) | In 4 conditions |
| DLL1delta like canonical Notch ligand 1 | Often (30–79%) | In 4 conditions |
| FGF8fibroblast growth factor 8 | Often (30–79%) | In 4 conditions |
| FGFR1fibroblast growth factor receptor 1 | Often (30–79%) | In 2 conditions |
| FGFR3fibroblast growth factor receptor 3 | Often (30–79%) | In 1 condition |
| FOXH1forkhead box H1 | Often (30–79%) | In 4 conditions |
| GAS1growth arrest specific 1 | Often (30–79%) | In 4 conditions |
| GLI2GLI family zinc finger 2 | Often (30–79%) | In 4 conditions |
| NODALnodal growth differentiation factor | Often (30–79%) | In 4 conditions |
| PLCH1phospholipase C eta 1 | Often (30–79%) | In 1 condition |
| PTCH1patched 1 | Often (30–79%) | In 4 conditions |
| SHHsonic hedgehog signaling molecule | Often (30–79%) | In 4 conditions |
| SIX3SIX homeobox 3 | Often (30–79%) | In 4 conditions |
| SMC1Astructural maintenance of chromosomes 1A | Often (30–79%) | In 1 condition |
| STAG2STAG2 cohesin complex component | Often (30–79%) | In 2 conditions |
| STILSTIL centriolar assembly protein | Often (30–79%) | In 4 conditions |
| TGIF1TGFB induced factor homeobox 1 | Often (30–79%) | In 4 conditions |
| TSEN54tRNA splicing endonuclease subunit 54 | Often (30–79%) | In 1 condition |
| ZIC2Zic family zinc finger 2 | Often (30–79%) | In 4 conditions |
| ARSLarylsulfatase L | Sometimes (5–29%) | In 1 condition |
| ATP1A3ATPase Na+/K+ transporting subunit alpha 3 | Sometimes (5–29%) | In 1 condition |
| CISD2CDGSH iron sulfur domain 2 | Sometimes (5–29%) | In 1 condition |
| MAGEL2MAGE family member L2 | Sometimes (5–29%) | In 3 conditions |
| NDNnecdin, MAGE family member | Sometimes (5–29%) | In 3 conditions |
| NR4A2nuclear receptor subfamily 4 group A member 2 | Sometimes (5–29%) | In 1 condition |
| OCA2OCA2 melanosomal transmembrane protein | Sometimes (5–29%) | In 3 conditions |
| SLC2A1solute carrier family 2 member 1 | Sometimes (5–29%) | In 1 condition |
| SNRPNsmall nuclear ribonucleoprotein polypeptide N | Sometimes (5–29%) | In 3 conditions |
| SYT1synaptotagmin 1 | Sometimes (5–29%) | In 1 condition |
| TBR1T-box brain transcription factor 1 | Sometimes (5–29%) | In 1 condition |
| TTC19tetratricopeptide repeat domain 19 | Sometimes (5–29%) | In 1 condition |
| WFS1wolframin ER transmembrane glycoprotein | Sometimes (5–29%) | In 1 condition |
Show 5 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| AHI1Abelson helper integration site 1 | Not recorded | In 1 condition |
| CEP290centrosomal protein 290 | Not recorded | In 1 condition |
| INPP5Einositol polyphosphate-5-phosphatase E | Not recorded | In 1 condition |
| RPGRIP1LRPGRIP1 like | Not recorded | In 1 condition |
| TMEM216transmembrane protein 216 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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