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Trait
Heart attack
Clinical name: Myocardial infarction
Necrosis of the myocardium caused by an obstruction of the blood supply to the heart and often associated with chest pain, shortness of breath, palpitations, and anxiety as well as characteristic EKG findings and elevation of serum markers including creatine kinase-MB fraction and troponin.
Summary
- Also called
- MI
- Body system
- Abnormality of the cardiovascular system
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This page as data
Add .json to the page's address, or ask for application/json, to read it as JSON.
library(jsonlite)
url <- "https://dantelabs.com/traits/myocardial-infarction.json"
page <- fromJSON(url)
page$trait$nameHeart attackHP:0001658
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Read the genes linked to Heart attack, and the rest of your genome, with one test.
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Get my Genome Test115 genes linked to Heart attack
Changes in these genes cause rare conditions in which Heart attack is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ABCC6ATP binding cassette subfamily C member 6 | Always | In 2 conditions |
| OAS22'-5'-oligoadenylate synthetase 2 | Always | In 1 condition |
| CALRcalreticulin | Very often (80–99%) | In 1 condition |
| DYRK1Bdual specificity tyrosine phosphorylation regulated kinase 1B | Very often (80–99%) | In 1 condition |
| JAK2Janus kinase 2 | Very often (80–99%) | In 2 conditions |
| MPLMPL proto-oncogene, thrombopoietin receptor | Very often (80–99%) | In 1 condition |
| SH2B3SH2B adaptor protein 3 | Very often (80–99%) | In 2 conditions |
| TET2tet methylcytosine dioxygenase 2 | Very often (80–99%) | In 1 condition |
| TP53tumor protein p53 | Very often (80–99%) | In 2 conditions |
| ABCG5ATP binding cassette subfamily G member 5 | Often (30–79%) | In 1 condition |
| ABCG8ATP binding cassette subfamily G member 8 | Often (30–79%) | In 1 condition |
| APOBapolipoprotein B | Often (30–79%) | In 1 condition |
| CELA2Achymotrypsin like elastase 2A | Often (30–79%) | In 1 condition |
| HLA-Bmajor histocompatibility complex, class I, B | Often (30–79%) | In 3 conditions |
| IL12Binterleukin 12B | Often (30–79%) | In 1 condition |
| LDLRlow density lipoprotein receptor | Often (30–79%) | In 1 condition |
| LDLRAP1low density lipoprotein receptor adaptor protein 1 | Often (30–79%) | In 1 condition |
| MEF2Amyocyte enhancer factor 2A | Often (30–79%) | In 1 condition |
| MLXMAX dimerization protein MLX | Often (30–79%) | In 1 condition |
| PCSK9proprotein convertase subtilisin/kexin type 9 | Often (30–79%) | In 1 condition |
| WRNWRN RecQ like helicase | Often (30–79%) | In 1 condition |
| ABCC9ATP binding cassette subfamily C member 9 | Sometimes (5–29%) | In 1 condition |
| ANTXR1ANTXR cell adhesion molecule 1 | Sometimes (5–29%) | In 1 condition |
| ATRXATRX chromatin remodeler | Sometimes (5–29%) | In 1 condition |
| BAZ1Bbromodomain adjacent to zinc finger domain 1B | Sometimes (5–29%) | In 1 condition |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Sometimes (5–29%) | In 3 conditions |
| BUD23BUD23 rRNA methyltransferase and ribosome maturation factor | Sometimes (5–29%) | In 1 condition |
| C4Acomplement C4A (Chido/Rodgers blood group) | Sometimes (5–29%) | In 1 condition |
| CCR1C-C motif chemokine receptor 1 | Sometimes (5–29%) | In 1 condition |
| CD4CD4 molecule | Sometimes (5–29%) | In 1 condition |
| CDH23cadherin related 23 | Sometimes (5–29%) | In 1 condition |
| CFTRCF transmembrane conductance regulator | Sometimes (5–29%) | In 1 condition |
| CLIP2CAP-Gly domain containing linker protein 2 | Sometimes (5–29%) | In 1 condition |
| DNAJC30DnaJ heat shock protein family (Hsp40) member C30 | Sometimes (5–29%) | In 1 condition |
| EIF4Heukaryotic translation initiation factor 4H | Sometimes (5–29%) | In 1 condition |
| ELNelastin | Sometimes (5–29%) | In 1 condition |
| ERAP1endoplasmic reticulum aminopeptidase 1 | Sometimes (5–29%) | In 1 condition |
| FASFas cell surface death receptor | Sometimes (5–29%) | In 1 condition |
| FKBP6FKBP prolyl isomerase family member 6 (inactive) | Sometimes (5–29%) | In 1 condition |
| GATA4GATA binding protein 4 | Sometimes (5–29%) | In 1 condition |
Show 75 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| GATA5GATA binding protein 5 | Sometimes (5–29%) | In 1 condition |
| GATA6GATA binding protein 6 | Sometimes (5–29%) | In 1 condition |
| GJA5gap junction protein alpha 5 | Sometimes (5–29%) | In 1 condition |
| GTF2Igeneral transcription factor IIi | Sometimes (5–29%) | In 1 condition |
| GTF2IRD1GTF2I repeat domain containing 1 | Sometimes (5–29%) | In 1 condition |
| GTF2IRD2GTF2I repeat domain containing 2 | Sometimes (5–29%) | In 1 condition |
| HGDhomogentisate 1,2-dioxygenase | Sometimes (5–29%) | In 1 condition |
| IFNGR1interferon gamma receptor 1 | Sometimes (5–29%) | In 1 condition |
| IKZF1IKAROS family zinc finger 1 | Sometimes (5–29%) | In 1 condition |
| IL10interleukin 10 | Sometimes (5–29%) | In 1 condition |
| IL12Ainterleukin 12A | Sometimes (5–29%) | In 1 condition |
| IL12A-AS1IL12A antisense RNA 1 | Sometimes (5–29%) | In 1 condition |
| IL23Rinterleukin 23 receptor | Sometimes (5–29%) | In 1 condition |
| IRF4interferon regulatory factor 4 | Sometimes (5–29%) | In 1 condition |
| KCNA5potassium voltage-gated channel subfamily A member 5 | Sometimes (5–29%) | In 1 condition |
| KCNE1potassium voltage-gated channel subfamily E regulatory subunit 1 | Sometimes (5–29%) | In 1 condition |
| KCNE2potassium voltage-gated channel subfamily E regulatory subunit 2 | Sometimes (5–29%) | In 1 condition |
| KCNJ2potassium inwardly rectifying channel subfamily J member 2 | Sometimes (5–29%) | In 1 condition |
| KCNJ3potassium inwardly rectifying channel subfamily J member 3 | Sometimes (5–29%) | In 1 condition |
| KCNJ5potassium inwardly rectifying channel subfamily J member 5 | Sometimes (5–29%) | In 1 condition |
| KCNQ1potassium voltage-gated channel subfamily Q member 1 | Sometimes (5–29%) | In 1 condition |
| KLRC4killer cell lectin like receptor C4 | Sometimes (5–29%) | In 1 condition |
| LIMK1LIM domain kinase 1 | Sometimes (5–29%) | In 1 condition |
| LMNAlamin A/C | Sometimes (5–29%) | In 2 conditions |
| MEFVMEFV innate immunity regulator, pyrin | Sometimes (5–29%) | In 2 conditions |
| METTL27methyltransferase like 27 | Sometimes (5–29%) | In 1 condition |
| MYL4myosin light chain 4 | Sometimes (5–29%) | In 1 condition |
| NCF1neutrophil cytosolic factor 1 | Sometimes (5–29%) | In 1 condition |
| NKX2-5NK2 homeobox 5 | Sometimes (5–29%) | In 1 condition |
| NKX2-6NK2 homeobox 6 | Sometimes (5–29%) | In 1 condition |
| NPPAnatriuretic peptide A | Sometimes (5–29%) | In 1 condition |
| NR3C1nuclear receptor subfamily 3 group C member 1 | Sometimes (5–29%) | In 1 condition |
| NUP155nucleoporin 155 | Sometimes (5–29%) | In 1 condition |
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Sometimes (5–29%) | In 1 condition |
| PITX2paired like homeodomain 2 | Sometimes (5–29%) | In 1 condition |
| PTPN11protein tyrosine phosphatase non-receptor type 11 | Sometimes (5–29%) | In 1 condition |
| RAF1Raf-1 proto-oncogene, serine/threonine kinase | Sometimes (5–29%) | In 1 condition |
| RFC2replication factor C subunit 2 | Sometimes (5–29%) | In 1 condition |
| SCN1Bsodium voltage-gated channel beta subunit 1 | Sometimes (5–29%) | In 1 condition |
| SCN2Bsodium voltage-gated channel beta subunit 2 | Sometimes (5–29%) | In 1 condition |
| SCN3Bsodium voltage-gated channel beta subunit 3 | Sometimes (5–29%) | In 1 condition |
| SCN4Bsodium voltage-gated channel beta subunit 4 | Sometimes (5–29%) | In 1 condition |
| SCN5Asodium voltage-gated channel alpha subunit 5 | Sometimes (5–29%) | In 1 condition |
| SCNN1Asodium channel epithelial 1 subunit alpha | Sometimes (5–29%) | In 1 condition |
| SCNN1Bsodium channel epithelial 1 subunit beta | Sometimes (5–29%) | In 1 condition |
| SCNN1Gsodium channel epithelial 1 subunit gamma | Sometimes (5–29%) | In 1 condition |
| SLC2A10solute carrier family 2 member 10 | Sometimes (5–29%) | In 1 condition |
| STAT4signal transducer and activator of transcription 4 | Sometimes (5–29%) | In 1 condition |
| STX1Asyntaxin 1A | Sometimes (5–29%) | In 1 condition |
| TBL2transducin beta like 2 | Sometimes (5–29%) | In 1 condition |
| THOC2THO complex subunit 2 | Sometimes (5–29%) | In 1 condition |
| TLR4toll like receptor 4 | Sometimes (5–29%) | In 1 condition |
| TMEM270transmembrane protein 270 | Sometimes (5–29%) | In 1 condition |
| TTNtitin | Sometimes (5–29%) | In 1 condition |
| UBAC2UBA domain containing 2 | Sometimes (5–29%) | In 1 condition |
| USP48ubiquitin specific peptidase 48 | Sometimes (5–29%) | In 1 condition |
| USP8ubiquitin specific peptidase 8 | Sometimes (5–29%) | In 1 condition |
| VPS37DVPS37D subunit of ESCRT-I | Sometimes (5–29%) | In 1 condition |
| ZMPSTE24zinc metallopeptidase STE24 | Sometimes (5–29%) | In 1 condition |
| ADAMTS13ADAM metallopeptidase with thrombospondin type 1 motif 13 | Rarely (1–4%) | In 1 condition |
| BCHEbutyrylcholinesterase | Rarely (1–4%) | In 1 condition |
| CCND1cyclin D1 | Rarely (1–4%) | In 1 condition |
| CTNNB1catenin beta 1 | Rarely (1–4%) | In 1 condition |
| MYH7myosin heavy chain 7 | Rarely (1–4%) | In 1 condition |
| MYH9myosin heavy chain 9 | Rarely (1–4%) | In 2 conditions |
| VHLvon Hippel-Lindau tumor suppressor | Rarely (1–4%) | In 1 condition |
| ABCA1ATP binding cassette subfamily A member 1 | Not recorded | In 2 conditions |
| CBScystathionine beta-synthase | Not recorded | In 1 condition |
| CEP19centrosomal protein 19 | Not recorded | In 1 condition |
| CYP27A1cytochrome P450 family 27 subfamily A member 1 | Not recorded | In 1 condition |
| ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 1 | Not recorded | In 1 condition |
| EPORerythropoietin receptor | Not recorded | In 1 condition |
| GLAgalactosidase alpha | Not recorded | In 1 condition |
| LPLlipoprotein lipase | Not recorded | In 1 condition |
| LRP6LDL receptor related protein 6 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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Log InAskGet Startedfrom $449
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks