Gene
RPS6KC1
ribosomal protein S6 kinase C1
- HGNC 10439↗(opens in a new tab)
- Ensembl gene ENSG00000136643↗(opens in a new tab)
- NCBI Gene 26750↗(opens in a new tab)
Summary
- Cytogenetic location
- 1q32.3
- Coordinates
- Chromosome 1: 213,051,241–213,274,774 (GRCh38)
- Exons
- 15 exons across 223.5 kb
- Protein
- 1,066 amino acids
- Also known as
- humS6PKh1, RSKL1
- MANE Select transcript
- ENST00000366960.8NM_012424.6
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How RPS6KC1 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 5.5 kb of the gene's 223.5 kb; 3,201 of those bases code for the protein.
Traits linked to RPS6KC1
The Human Phenotype Ontology lists these as features of the rare conditions RPS6KC1 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Abnormal gait
- Dystonia
- Jerking
- Mental deterioration
- Peripheral axonal neuropathy
- Tremor
- Underdevelopment of part of brain called corpus callosum
- IQ between 34 and 49
Show 18 more traits
- Epilepsy
- Increased reflexes
- Mild global developmental delay
- Moderate global developmental delay
- Reduced cerebral white matter volume
- Thin corpus callosum
- Aggressive behavior
- Anxiety
- Attention deficit
- Autism spectrum disorder
- Cerebellar vermis atrophy
- Cerebellar vermis hypoplasia
- Colpocephaly
- Depression
- Intellectual disability, mild
- Loss of developmental milestones
- Restricted or repetitive behaviors or interests
- Shyness
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). RPS6KC1 gene: ribosomal protein S6 kinase C1. Retrieved 17 October 2026, from https://dantelabs.com/genes/rps6kc1
Dante Labs. RPS6KC1 gene: ribosomal protein S6 kinase C1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/rps6kc1
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