Parkinson Disease
A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus. Signs and symptoms include tremor which is most pronounced during rest, muscle rigidity, slowing of the voluntary movements, a tendency to fall back, and a mask-like facial expression.
Mit változtat a diagnózis
LRRK2 kinase inhibitor trials, substrate reduction therapy for GBA variants, α-synuclein-targeted approaches, dopaminergic medications, levodopa
Más néven
paralysis agitans; Parkinson's disease; PD
27 kapcsolódó altípust tartalmaz ↓Altípusok elrejtése ↑
- autosomal dominant Parkinson disease 1
- autosomal dominant Parkinson disease 4
- autosomal dominant Parkinson disease 8
- autosomal recessive early-onset Parkinson disease 23
- autosomal recessive early-onset Parkinson disease 6
- autosomal recessive early-onset Parkinson disease 7
- autosomal recessive juvenile Parkinson disease 2
- autosomal recessive Parkinson disease 14
- early-onset Parkinson disease 20
- juvenile onset Parkinson disease 19A
- juvenile-onset Parkinson disease
- Kufor-Rakeb syndrome
- late-onset Parkinson disease
- paralysis agitans, juvenile, of Hunt
- Parkinson disease 10
- Parkinson disease 12
- Parkinson disease 16
- Parkinson disease 17
- Parkinson disease 19B, early-onset
- Parkinson disease 21
- Parkinson disease 22, autosomal dominant
- Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development
- Parkinson disease 3, autosomal dominant
- Parkinson disease, mitochondrial
- parkinsonian-pyramidal syndrome
- parkinsonism due to ATP13A2 deficiency
- young-onset Parkinson disease
