Autoimmune lymphoproliferative syndrome
Chronic lymph node and spleen enlargement, autoimmune cytopenias and raised double-negative T cells caused by changes in FAS, FASLG, CASP10 and related apoptosis genes.
Mit változtat a diagnózis
Diagnosis allows sirolimus or other immunosuppression for cytopenias, avoidance of unnecessary splenectomy, lymphoma vigilance and family testing.
Más néven
ALPS; ALPS (autoimmune lymphoproliferative syndrome); autoimmune lymphoproliferative syndrome type 1, autosomal dominant; Canale-Smith syndrome; FAS deficiency
9 kapcsolódó altípust tartalmaz ↓Altípusok elrejtése ↑
- autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency
- autoimmune lymphoproliferative syndrome type 1
- autoimmune lymphoproliferative syndrome type 2A
- autoimmune lymphoproliferative syndrome type 2B
- autoimmune lymphoproliferative syndrome type 4
- autoimmune lymphoproliferative syndrome, type III caused by mutation in PRKCD
- Castleman-Kojima disease
- FAS-related autoimmune lymphoproliferative immune disorder
- type 3 autoimmune lymphoproliferative syndrome
