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Gene

SH3PXD2B

SH3 and PX domains 2B

Summary

Cytogenetic location
5q35.1
Coordinates
Chromosome 5: 172,333,499–172,454,525 (GRCh38)
Exons
13 exons across 121 kb
Protein
911 amino acids
Also known as
FLJ20831
Previous symbols
KIAA1295
MANE Select transcript
ENST00000311601.6NM_001017995.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SH3PXD2B yet. The test sequences your whole genome, so your data includes it all the same.

How SH3PXD2B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 5, with a bracket where SH3PXD2B sits. SH3PXD2B and 7 genes near it on chromosome 5, from 171,894,012 to 172,894,011.Chromosome 55q35.1p15.33p15.32p15.31p15.2p15.1p14.3p14.2p14.1p13.3p13.2p13.1p12p11q11.1q11.2q12.1q12.2q12.3q13.1q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q31.1q31.2q31.3q32q33.1q33.2q33.3q34q35.1q35.2q35.3172 Mb172.2 Mb172.4 Mb172.6 Mb172.8 MbFBXW11: 171,844,094–172,006,907, reverse strandFBXW11STK10: 172,042,079–172,188,411, reverse strandSTK10EFCAB9: 172,194,172–172,203,454, forward strandEFCAB9UBTD2: 172,209,642–172,284,102, reverse strandUBTD2SH3PXD2B: 172,333,499–172,454,525, reverse strandSH3PXD2BNEURL1B: 172,641,230–172,691,540, forward strandNEURL1BDUSP1: 172,766,992–172,771,198, reverse strandDUSP1ERGIC1: 172,834,251–172,952,792, forward strandERGIC1Diagram of SH3PXD2B: 13 exons on the reverse strand of chromosome 5Exon 10: 1 known disease-causing siteExon 8: 1 known disease-causing siteExon 2: 1 known disease-causing siteExon 13: 172,333,499–172,339,916, 6,418 basesExon 12: 172,346,136–172,346,261, 126 basesExon 11: 172,347,283–172,347,332, 50 basesExon 10: 172,350,363–172,350,589, 227 basesExon 9: 172,353,888–172,354,005, 118 basesExon 8: 172,358,773–172,358,877, 105 basesExon 7: 172,362,735–172,362,869, 135 basesExon 6: 172,373,790–172,373,815, 26 basesExon 5: 172,382,036–172,382,127, 92 basesExon 4: 172,394,563–172,394,639, 77 basesExon 3: 172,406,277–172,406,352, 76 basesExon 2: 172,422,416–172,422,496, 81 basesExon 1: 172,454,278–172,454,525, 248 bases131210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.8 kb of the gene's 121 kb; 2,736 of those bases code for the protein.

How a genome test reads SH3PXD2B

4

positions in SH3PXD2B where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 121 kb of SH3PXD2B, introns included, not only the 7.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SH3PXD2B gene: SH3 and PX domains 2B. Retrieved 17 October 2026, from https://dantelabs.com/genes/sh3pxd2b

Vancouver

Dante Labs. SH3PXD2B gene: SH3 and PX domains 2B [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/sh3pxd2b

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