Trait
Back knee
Clinical name: Genu recurvatum
An abnormally increased extension of the knee joint, so that the knee can bend backwards.
Summary
- Also called
- Knee hyperextension, Genu recurvata
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Get my Genome Test35 genes linked to Back knee
Changes in these genes cause rare conditions in which Back knee is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| HRASHRas proto-oncogene, GTPase | Very often (80–99%) | In 1 condition |
| KRASKRas proto-oncogene, GTPase | Very often (80–99%) | In 1 condition |
| NRASNRAS proto-oncogene, GTPase | Very often (80–99%) | In 1 condition |
| PTENphosphatase and tensin homolog | Very often (80–99%) | In 1 condition |
| ANO5anoctamin 5 | Often (30–79%) | In 1 condition |
| CANT1calcium activated nucleotidase 1 | Often (30–79%) | In 1 condition |
| CDT1chromatin licensing and DNA replication factor 1 | Often (30–79%) | In 1 condition |
| CFL2cofilin 2 | Often (30–79%) | In 1 condition |
| CHST3carbohydrate sulfotransferase 3 | Often (30–79%) | In 1 condition |
| COL1A2collagen type I alpha 2 chain | Often (30–79%) | In 2 conditions |
| CSGALNACT1chondroitin sulfate N-acetylgalactosaminyltransferase 1 | Often (30–79%) | In 1 condition |
| ORC1origin recognition complex subunit 1 | Often (30–79%) | In 1 condition |
| PRR12proline rich 12 | Often (30–79%) | In 1 condition |
| SH3PXD2BSH3 and PX domains 2B | Often (30–79%) | In 1 condition |
| XYLT1xylosyltransferase 1 | Often (30–79%) | In 1 condition |
| AP4B1adaptor related protein complex 4 subunit beta 1 | Sometimes (5–29%) | In 2 conditions |
| ASCC3activating signal cointegrator 1 complex subunit 3 | Sometimes (5–29%) | In 1 condition |
| B4GALT7beta-1,4-galactosyltransferase 7 | Sometimes (5–29%) | In 1 condition |
| FGD1FYVE, RhoGEF and PH domain containing 1 | Sometimes (5–29%) | In 1 condition |
| GRIA3glutamate ionotropic receptor AMPA type subunit 3 | Sometimes (5–29%) | In 1 condition |
| MAN2C1mannosidase alpha class 2C member 1 | Sometimes (5–29%) | In 1 condition |
| MCOLN1mucolipin TRP cation channel 1 | Sometimes (5–29%) | In 1 condition |
| WASF1WASP family member 1 | Sometimes (5–29%) | In 1 condition |
| ALDH18A1aldehyde dehydrogenase 18 family member A1 | Rarely (1–4%) | In 1 condition |
| AP4E1adaptor related protein complex 4 subunit epsilon 1 | Rarely (1–4%) | In 1 condition |
| AP4M1adaptor related protein complex 4 subunit mu 1 | Rarely (1–4%) | In 1 condition |
| AP4S1adaptor related protein complex 4 subunit sigma 1 | Rarely (1–4%) | In 1 condition |
| ELNelastin | Rarely (1–4%) | In 1 condition |
| FBLN5fibulin 5 | Rarely (1–4%) | In 1 condition |
| COMPcartilage oligomeric matrix protein | Not recorded | In 1 condition |
| CTDP1CTD phosphatase 1 | Not recorded | In 1 condition |
| FBN1fibrillin 1 | Not recorded | In 1 condition |
| SKISKI proto-oncogene | Not recorded | In 1 condition |
| SLC6A9solute carrier family 6 member 9 | Not recorded | In 1 condition |
| TRIP11thyroid hormone receptor interactor 11 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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