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Gene

FBXW11

F-box and WD repeat domain containing 11

Summary

Cytogenetic location
5q35.1
Coordinates
Chromosome 5: 171,861,549–172,006,638 (GRCh38)
Exons
14 exons across 145.1 kb
Protein
563 amino acids
Also known as
KIAA0696, Fbw1b, BTRCP2, BTRC2, Hos, Fbw11
Previous symbols
FBXW1B
MANE Select transcript
ENST00000517395.6NM_001378974.1
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads FBXW11 yet. The test sequences your whole genome, so your data includes it all the same.

How FBXW11 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 5, with a bracket where FBXW11 sits. FBXW11 and 6 genes near it on chromosome 5, from 171,434,094 to 172,434,093.Chromosome 55q35.1p15.33p15.32p15.31p15.2p15.1p14.3p14.2p14.1p13.3p13.2p13.1p12p11q11.1q11.2q12.1q12.2q12.3q13.1q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q31.1q31.2q31.3q32q33.1q33.2q33.3q34q35.1q35.2q35.3171.6 Mb171.8 Mb172 Mb172.2 Mb172.4 MbFGF18: 171,419,637–171,457,626, forward strandFGF18SMIM23: 171,782,432–171,796,126, forward strandSMIM23FBXW11: 171,861,549–172,006,638, reverse strandFBXW11STK10: 172,042,079–172,188,411, reverse strandSTK10EFCAB9: 172,194,172–172,203,454, forward strandEFCAB9UBTD2: 172,209,642–172,284,102, reverse strandUBTD2SH3PXD2B: 172,323,171–172,454,536, reverse strandSH3PXD2BDiagram of FBXW11: 14 exons on the reverse strand of chromosome 5Exon 11: 2 known disease-causing sitesExon 10: 1 known disease-causing siteExon 9: 2 known disease-causing sitesExon 8: 1 known disease-causing siteExon 7: 2 known disease-causing sitesExon 14: 171,861,549–171,864,101, 2,553 basesExon 13: 171,868,610–171,868,796, 187 basesExon 12: 171,869,729–171,869,807, 79 basesExon 11: 171,870,748–171,870,858, 111 basesExon 10: 171,872,872–171,872,990, 119 basesExon 9: 171,876,285–171,876,534, 250 basesExon 8: 171,878,011–171,878,129, 119 basesExon 7: 171,891,467–171,891,604, 138 basesExon 6: 171,899,004–171,899,094, 91 basesExon 5: 171,899,914–171,900,100, 187 basesExon 4: 171,910,572–171,910,797, 226 basesExon 3: 171,914,343–171,914,405, 63 basesExon 2: 171,957,597–171,957,698, 102 basesExon 1: 172,006,458–172,006,638, 181 bases1410515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.4 kb of the gene's 145.1 kb; 1,692 of those bases code for the protein.

How a genome test reads FBXW11

8

positions in FBXW11 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 145.1 kb of FBXW11, introns included, not only the 4.4 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). FBXW11 gene: F-box and WD repeat domain containing 11. Retrieved 16 October 2026, from https://dantelabs.com/genes/fbxw11

Vancouver

Dante Labs. FBXW11 gene: F-box and WD repeat domain containing 11 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/fbxw11

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