Trait
Front half of foot turns inward
Clinical name: Metatarsus adductus
The metatarsals are deviated medially (tibially), that is, the bones in the front half of the foot bend or turn in toward the body.
Summary
- Also called
- Forefoot varus, Metatarsus adductovarsus, Metatarsus varus, Sickle foot, Sickled feet
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test56 genes linked to Front half of foot turns inward
Changes in these genes cause rare conditions in which Front half of foot turns inward is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ELFN1extracellular leucine rich repeat and fibronectin type III domain containing 1 | Always | In 1 condition |
| RFC4replication factor C subunit 4 | Always | In 1 condition |
| TOP2BDNA topoisomerase II beta | Always | In 1 condition |
| UBAP2Lubiquitin associated protein 2 like | Always | In 1 condition |
| BCL11ABCL11 transcription factor A | Often (30–79%) | In 1 condition |
| FGD1FYVE, RhoGEF and PH domain containing 1 | Often (30–79%) | In 1 condition |
| FIG4FIG4 phosphoinositide 5-phosphatase | Often (30–79%) | In 1 condition |
| GUSBglucuronidase beta | Often (30–79%) | In 2 conditions |
| RELREL proto-oncogene, NF-kB subunit | Often (30–79%) | In 1 condition |
| SLC26A2solute carrier family 26 member 2 | Often (30–79%) | In 1 condition |
| VAC14VAC14 component of PIKFYVE complex | Often (30–79%) | In 1 condition |
| XPO1exportin 1 | Often (30–79%) | In 1 condition |
| CACHD1cache domain containing 1 | Sometimes (5–29%) | In 1 condition |
| DHCR2424-dehydrocholesterol reductase | Sometimes (5–29%) | In 1 condition |
| DLK1delta like non-canonical Notch ligand 1 | Sometimes (5–29%) | In 1 condition |
| FBN1fibrillin 1 | Sometimes (5–29%) | In 1 condition |
| FIBPFGF1 intracellular binding protein | Sometimes (5–29%) | In 1 condition |
| GLI3GLI family zinc finger 3 | Sometimes (5–29%) | In 1 condition |
| LMNB2lamin B2 | Sometimes (5–29%) | In 1 condition |
| MAPK1mitogen-activated protein kinase 1 | Sometimes (5–29%) | In 1 condition |
| MEG3maternally expressed 3 | Sometimes (5–29%) | In 1 condition |
| NALCNsodium leak channel, non-selective | Sometimes (5–29%) | In 1 condition |
| PIEZO2piezo type mechanosensitive ion channel component 2 | Sometimes (5–29%) | In 1 condition |
| RTL1retrotransposon Gag like 1 | Sometimes (5–29%) | In 1 condition |
| SLC35A2solute carrier family 35 member A2 | Sometimes (5–29%) | In 1 condition |
| SOX9SRY-box transcription factor 9 | Sometimes (5–29%) | In 1 condition |
| TUBB3tubulin beta 3 class III | Sometimes (5–29%) | In 1 condition |
| WDR26WD repeat domain 26 | Sometimes (5–29%) | In 1 condition |
| ZFXzinc finger protein X-linked | Sometimes (5–29%) | In 1 condition |
| B3GALT6beta-1,3-galactosyltransferase 6 | Not recorded | In 1 condition |
| B3GAT3beta-1,3-glucuronyltransferase 3 | Not recorded | In 1 condition |
| CHST3carbohydrate sulfotransferase 3 | Not recorded | In 1 condition |
| CPLX1complexin 1 | Not recorded | In 1 condition |
| CTBP1C-terminal binding protein 1 | Not recorded | In 1 condition |
| DDR2discoidin domain receptor tyrosine kinase 2 | Not recorded | In 1 condition |
| DHCR77-dehydrocholesterol reductase | Not recorded | In 1 condition |
| EZH2enhancer of zeste 2 polycomb repressive complex 2 subunit | Not recorded | In 1 condition |
| FBN2fibrillin 2 | Not recorded | In 1 condition |
| FGFRL1fibroblast growth factor receptor like 1 | Not recorded | In 1 condition |
| LETM1leucine zipper and EF-hand containing transmembrane protein 1 | Not recorded | In 1 condition |
Show 16 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| MYH8myosin heavy chain 8 | Not recorded | In 1 condition |
| NSD2nuclear receptor binding SET domain protein 2 | Not recorded | In 1 condition |
| PEX1peroxisomal biogenesis factor 1 | Not recorded | In 1 condition |
| PEX2peroxisomal biogenesis factor 2 | Not recorded | In 1 condition |
| PEX5peroxisomal biogenesis factor 5 | Not recorded | In 1 condition |
| RAB23RAB23, member RAS oncogene family | Not recorded | In 1 condition |
| RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2 | Not recorded | In 1 condition |
| SH3PXD2BSH3 and PX domains 2B | Not recorded | In 1 condition |
| SKISKI proto-oncogene | Not recorded | In 1 condition |
| TNNI2troponin I2, fast skeletal type | Not recorded | In 1 condition |
| TNNT3troponin T3, fast skeletal type | Not recorded | In 1 condition |
| TRPV4transient receptor potential cation channel subfamily V member 4 | Not recorded | In 1 condition |
| UBE3Bubiquitin protein ligase E3B | Not recorded | In 1 condition |
| WNT7AWnt family member 7A | Not recorded | In 1 condition |
| XYLT1xylosyltransferase 1 | Not recorded | In 1 condition |
| ZBTB20zinc finger and BTB domain containing 20 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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