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Trait

Increased total basophil count

Abnormal increase of absolute number of basophils in the blood, per microliter, compared to a reference range for a given sex and age-group.

HPO HP:0031807

Summary

Also called
Basophilia, Increased basophil count
Body system
Abnormality of blood and blood-forming tissuesAbnormality of the immune system

4 genes linked to Increased total basophil count

Changes in these genes cause rare conditions in which Increased total basophil count is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
ASXL1ASXL transcriptional regulator 1Sometimes (5–29%)In 1 condition
KITKIT proto-oncogene, receptor tyrosine kinaseSometimes (5–29%)In 1 condition
SRSF2serine and arginine rich splicing factor 2Sometimes (5–29%)In 1 condition
TET2tet methylcytosine dioxygenase 2Sometimes (5–29%)In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormal total basophil count

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

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