Trait
Chronic lymphatic leukemia
A chronic lymphocytic/lymphatic/lymphoblastic leukemia (CLL) is a neoplastic disease characterized by proliferation and accumulation (blood, marrow and lymphoid organs) of morphologically mature but immunologically dysfunctional lymphocytes. A CLL is always a B-cell lymphocytic leukemia as there are no reports of cases of T-cell lymphocytic leukemias.
Summary
- Also called
- Chronic lymphatic leukaemia, Chronic lymphocytic leukaemia, Chronic lymphocytic leukemia
Reference genomeGRCh38hg38
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Get my Genome Test16 genes linked to Chronic lymphatic leukemia
Changes in these genes cause rare conditions in which Chronic lymphatic leukemia is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ADARadenosine deaminase RNA specific | Rarely (1–4%) | In 1 condition |
| ASXL1ASXL transcriptional regulator 1 | Rarely (1–4%) | In 1 condition |
| IFIH1interferon induced with helicase C domain 1 | Rarely (1–4%) | In 1 condition |
| KITKIT proto-oncogene, receptor tyrosine kinase | Rarely (1–4%) | In 1 condition |
| LSM11LSM11, U7 small nuclear RNA associated | Rarely (1–4%) | In 1 condition |
| MEFVMEFV innate immunity regulator, pyrin | Rarely (1–4%) | In 1 condition |
| PIK3R1phosphoinositide-3-kinase regulatory subunit 1 | Rarely (1–4%) | In 1 condition |
| PTPN6protein tyrosine phosphatase non-receptor type 6 | Rarely (1–4%) | In 1 condition |
| RNASEH2Aribonuclease H2 subunit A | Rarely (1–4%) | In 1 condition |
| RNASEH2Bribonuclease H2 subunit B | Rarely (1–4%) | In 1 condition |
| RNASEH2Cribonuclease H2 subunit C | Rarely (1–4%) | In 1 condition |
| RNU7-1RNA, U7 small nuclear 1 | Rarely (1–4%) | In 1 condition |
| SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 | Rarely (1–4%) | In 1 condition |
| SRSF2serine and arginine rich splicing factor 2 | Rarely (1–4%) | In 1 condition |
| TET2tet methylcytosine dioxygenase 2 | Rarely (1–4%) | In 1 condition |
| TREX1three prime repair exonuclease 1 | Rarely (1–4%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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