Trait
Cancer of lymphatic system
Clinical name: Lymphoma
A cancer originating in lymphocytes and presenting as a solid tumor of lymhpoid cells.
Summary
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test83 genes linked to Cancer of lymphatic system
Changes in these genes cause rare conditions in which Cancer of lymphatic system is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| FRYLFRY like transcription coactivator | Always | In 1 condition |
| PTCRApre T cell antigen receptor alpha | Always | In 1 condition |
| TET2tet methylcytosine dioxygenase 2 | Always | In 2 conditions |
| BCL2BCL2 apoptosis regulator | Very often (80–99%) | In 1 condition |
| BCL6BCL6 transcription repressor | Very often (80–99%) | In 1 condition |
| CD28CD28 molecule | Very often (80–99%) | In 2 conditions |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Very often (80–99%) | In 3 conditions |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Very often (80–99%) | In 1 condition |
| IGHimmunoglobulin heavy locus | Very often (80–99%) | In 1 condition |
| MYD88MYD88 innate immune signal transduction adaptor | Very often (80–99%) | In 2 conditions |
| TNFRSF1BTNF receptor superfamily member 1B | Very often (80–99%) | In 2 conditions |
| ITPR3inositol 1,4,5-trisphosphate receptor type 3 | Often (30–79%) | In 1 condition |
| LIG4DNA ligase 4 | Often (30–79%) | In 1 condition |
| MSH6mutS homolog 6 | Often (30–79%) | In 1 condition |
| ACDACD shelterin complex subunit and telomerase recruitment factor | Sometimes (5–29%) | In 1 condition |
| ADAadenosine deaminase | Sometimes (5–29%) | In 1 condition |
| ASXL1ASXL transcriptional regulator 1 | Sometimes (5–29%) | In 1 condition |
| BLMBLM RecQ like helicase | Sometimes (5–29%) | In 2 conditions |
| CD27CD27 molecule | Sometimes (5–29%) | In 1 condition |
| CDKN2Acyclin dependent kinase inhibitor 2A | Sometimes (5–29%) | In 1 condition |
| CHD7chromodomain helicase DNA binding protein 7 | Sometimes (5–29%) | In 1 condition |
| CHEK2checkpoint kinase 2 | Sometimes (5–29%) | In 1 condition |
| CTC1CST telomere replication complex component 1 | Sometimes (5–29%) | In 1 condition |
| DCLRE1CDNA cross-link repair 1C | Sometimes (5–29%) | In 1 condition |
| DIAPH1diaphanous related formin 1 | Sometimes (5–29%) | In 1 condition |
| DKC1dyskerin pseudouridine synthase 1 | Sometimes (5–29%) | In 1 condition |
| DNASE1L3deoxyribonuclease 1L3 | Sometimes (5–29%) | In 1 condition |
| IL2RGinterleukin 2 receptor subunit gamma | Sometimes (5–29%) | In 2 conditions |
| IL7Rinterleukin 7 receptor | Sometimes (5–29%) | In 1 condition |
| KIF11kinesin family member 11 | Sometimes (5–29%) | In 1 condition |
| KITKIT proto-oncogene, receptor tyrosine kinase | Sometimes (5–29%) | In 1 condition |
| LRBALPS responsive beige-like anchor protein | Sometimes (5–29%) | In 1 condition |
| MDM2MDM2 proto-oncogene | Sometimes (5–29%) | In 1 condition |
| MLH1mutL homolog 1 | Sometimes (5–29%) | In 1 condition |
| NBNnibrin | Sometimes (5–29%) | In 2 conditions |
| NHP2NHP2 ribonucleoprotein | Sometimes (5–29%) | In 1 condition |
| NOP10NOP10 ribonucleoprotein | Sometimes (5–29%) | In 1 condition |
| NPM1nucleophosmin 1 | Sometimes (5–29%) | In 1 condition |
| NUDCD3NudC domain containing 3 | Sometimes (5–29%) | In 1 condition |
| PARNpoly(A)-specific ribonuclease | Sometimes (5–29%) | In 1 condition |
Show 43 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| PGM3phosphoglucomutase 3 | Sometimes (5–29%) | In 1 condition |
| PSMB10proteasome 20S subunit beta 10 | Sometimes (5–29%) | In 1 condition |
| PTENphosphatase and tensin homolog | Sometimes (5–29%) | In 1 condition |
| RAG1recombination activating 1 | Sometimes (5–29%) | In 1 condition |
| RAG2recombination activating 2 | Sometimes (5–29%) | In 1 condition |
| RECQL4RecQ like helicase 4 | Sometimes (5–29%) | In 2 conditions |
| RMRPRNA component of mitochondrial RNA processing endoribonuclease | Sometimes (5–29%) | In 2 conditions |
| RTEL1regulator of telomere elongation helicase 1 | Sometimes (5–29%) | In 1 condition |
| SH2D1ASH2 domain containing 1A | Sometimes (5–29%) | In 1 condition |
| SRSF2serine and arginine rich splicing factor 2 | Sometimes (5–29%) | In 1 condition |
| STAT3signal transducer and activator of transcription 3 | Sometimes (5–29%) | In 1 condition |
| TERCtelomerase RNA component | Sometimes (5–29%) | In 1 condition |
| TERTtelomerase reverse transcriptase | Sometimes (5–29%) | In 1 condition |
| TINF2TERF1 interacting nuclear factor 2 | Sometimes (5–29%) | In 1 condition |
| TP53tumor protein p53 | Sometimes (5–29%) | In 1 condition |
| TP63tumor protein p63 | Sometimes (5–29%) | In 1 condition |
| TYMSthymidylate synthetase | Sometimes (5–29%) | In 1 condition |
| USB1U6 snRNA biogenesis phosphodiesterase 1 | Sometimes (5–29%) | In 1 condition |
| WASWASP actin nucleation promoting factor | Sometimes (5–29%) | In 1 condition |
| WRAP53WD repeat containing antisense to TP53 | Sometimes (5–29%) | In 1 condition |
| XIAPX-linked inhibitor of apoptosis | Sometimes (5–29%) | In 1 condition |
| IGHG2immunoglobulin heavy constant gamma 2 (G2m marker) | Rarely (1–4%) | In 1 condition |
| IGKCimmunoglobulin kappa constant | Rarely (1–4%) | In 1 condition |
| ZAP70zeta chain of T cell receptor associated protein kinase 70 | Rarely (1–4%) | In 1 condition |
| ATMATM serine/threonine kinase | Not recorded | In 1 condition |
| BCL10BCL10 immune signaling adaptor | Not recorded | In 1 condition |
| CASP10caspase 10 | Not recorded | In 1 condition |
| CD19CD19 molecule | Not recorded | In 1 condition |
| CR2complement C3d receptor 2 | Not recorded | In 1 condition |
| DDX41DEAD-box helicase 41 | Not recorded | In 1 condition |
| HLA-DQA1major histocompatibility complex, class II, DQ alpha 1 | Not recorded | In 1 condition |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Not recorded | In 1 condition |
| ICOSinducible T cell costimulator | Not recorded | In 1 condition |
| MAGT1magnesium transporter 1 | Not recorded | In 1 condition |
| NRASNRAS proto-oncogene, GTPase | Not recorded | In 1 condition |
| PNPpurine nucleoside phosphorylase | Not recorded | In 1 condition |
| PRF1perforin 1 | Not recorded | In 1 condition |
| RAD54BRAD54 homolog B | Not recorded | In 1 condition |
| RAD54LRAD54 like | Not recorded | In 1 condition |
| RB1RB transcriptional corepressor 1 | Not recorded | In 1 condition |
| RUNX1RUNX family transcription factor 1 | Not recorded | In 1 condition |
| TNFRSF13BTNF receptor superfamily member 13B | Not recorded | In 1 condition |
| TNFRSF13CTNF receptor superfamily member 13C | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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