Trait
Blood cancer
Clinical name: Leukemia
A cancer of the blood and bone marrow characterized by an abnormal proliferation of leukocytes.
Summary
- Also called
- Leukaemia
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Blood cancer, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test49 genes linked to Blood cancer
Changes in these genes cause rare conditions in which Blood cancer is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| KLF1KLF transcription factor 1 | Always | In 1 condition |
| RPL17ribosomal protein L17 | Always | In 1 condition |
| SOX17SRY-box transcription factor 17 | Always | In 1 condition |
| MYD88MYD88 innate immune signal transduction adaptor | Very often (80–99%) | In 2 conditions |
| BRD4bromodomain containing 4 | Often (30–79%) | In 1 condition |
| H4C9H4 clustered histone 9 | Often (30–79%) | In 1 condition |
| NUTM1NUT midline carcinoma family member 1 | Often (30–79%) | In 1 condition |
| ASXL1ASXL transcriptional regulator 1 | Sometimes (5–29%) | In 1 condition |
| CBLCbl proto-oncogene | Sometimes (5–29%) | In 1 condition |
| CDKN2Acyclin dependent kinase inhibitor 2A | Sometimes (5–29%) | In 1 condition |
| CHEK2checkpoint kinase 2 | Sometimes (5–29%) | In 1 condition |
| CLPBClpB family mitochondrial disaggregase | Sometimes (5–29%) | In 1 condition |
| DNAJC21DnaJ heat shock protein family (Hsp40) member C21 | Sometimes (5–29%) | In 1 condition |
| EFL1elongation factor like GTPase 1 | Sometimes (5–29%) | In 1 condition |
| ELANEelastase, neutrophil expressed | Sometimes (5–29%) | In 1 condition |
| GFI1growth factor independent 1 transcriptional repressor | Sometimes (5–29%) | In 1 condition |
| KIF11kinesin family member 11 | Sometimes (5–29%) | In 1 condition |
| LZTR1leucine zipper like post translational regulator 1 | Sometimes (5–29%) | In 1 condition |
| MDM2MDM2 proto-oncogene | Sometimes (5–29%) | In 1 condition |
| MLH1mutL homolog 1 | Sometimes (5–29%) | In 1 condition |
| NOP10NOP10 ribonucleoprotein | Sometimes (5–29%) | In 1 condition |
| RUNX1RUNX family transcription factor 1 | Sometimes (5–29%) | In 1 condition |
| SBDSSBDS ribosome maturation factor | Sometimes (5–29%) | In 1 condition |
| SCN10Asodium voltage-gated channel alpha subunit 10 | Sometimes (5–29%) | In 1 condition |
| SCN11Asodium voltage-gated channel alpha subunit 11 | Sometimes (5–29%) | In 1 condition |
| SCN9Asodium voltage-gated channel alpha subunit 9 | Sometimes (5–29%) | In 1 condition |
| SRP19signal recognition particle 19 | Sometimes (5–29%) | In 1 condition |
| SRSF2serine and arginine rich splicing factor 2 | Sometimes (5–29%) | In 1 condition |
| TCIRG1T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 | Sometimes (5–29%) | In 1 condition |
| TET2tet methylcytosine dioxygenase 2 | Sometimes (5–29%) | In 1 condition |
| TP53tumor protein p53 | Sometimes (5–29%) | In 1 condition |
| ANAPC1anaphase promoting complex subunit 1 | Rarely (1–4%) | In 1 condition |
| NF1neurofibromin 1 | Rarely (1–4%) | In 1 condition |
| RECQL4RecQ like helicase 4 | Rarely (1–4%) | In 1 condition |
| ATMATM serine/threonine kinase | Not recorded | In 1 condition |
| BLMBLM RecQ like helicase | Not recorded | In 1 condition |
| BUB1BBUB1 mitotic checkpoint serine/threonine kinase B | Not recorded | In 1 condition |
| CREBBPCREB binding lysine acetyltransferase | Not recorded | In 1 condition |
| EP300EP300 lysine acetyltransferase | Not recorded | In 1 condition |
| ERBB3erb-b2 receptor tyrosine kinase 3 | Not recorded | In 1 condition |
Show 9 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| FANCAFA complementation group A | Not recorded | In 1 condition |
| FANCD2FA complementation group D2 | Not recorded | In 1 condition |
| FANCEFA complementation group E | Not recorded | In 1 condition |
| FANCGFA complementation group G | Not recorded | In 1 condition |
| GATA2GATA binding protein 2 | Not recorded | In 1 condition |
| NRASNRAS proto-oncogene, GTPase | Not recorded | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Not recorded | In 1 condition |
| RB1RB transcriptional corepressor 1 | Not recorded | In 1 condition |
| TERCtelomerase RNA component | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks