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Trait
Decreased width of the skull
Clinical name: Biparietal narrowing
A narrowing of the biparietal diameter (i.e., of the transverse distance between the protuberances of the two parietal bones of the skull).
Summary
Decreased width of the skullHP:0004422
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Read the genes linked to Decreased width of the skull, and the rest of your genome, with one test.
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Get my Genome Test64 genes linked to Decreased width of the skull
Changes in these genes cause rare conditions in which Decreased width of the skull is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CD96CD96 molecule | Very often (80–99%) | In 1 condition |
| HRASHRas proto-oncogene, GTPase | Very often (80–99%) | In 1 condition |
| KRASKRas proto-oncogene, GTPase | Very often (80–99%) | In 2 conditions |
| NRASNRAS proto-oncogene, GTPase | Very often (80–99%) | In 1 condition |
| PPP2R3Cprotein phosphatase 2 regulatory subunit B''gamma | Very often (80–99%) | In 1 condition |
| ZNHIT3zinc finger HIT-type containing 3 | Very often (80–99%) | In 1 condition |
| AHI1Abelson helper integration site 1 | Often (30–79%) | In 2 conditions |
| ARL13BARF like GTPase 13B | Often (30–79%) | In 1 condition |
| ARL3ARF like GTPase 3 | Often (30–79%) | In 1 condition |
| ARMC9armadillo repeat containing 9 | Often (30–79%) | In 1 condition |
| B9D1B9 domain containing 1 | Often (30–79%) | In 1 condition |
| B9D2B9 domain containing 2 | Often (30–79%) | In 1 condition |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Often (30–79%) | In 1 condition |
| CBY1chibby 1, beta catenin antagonist | Often (30–79%) | In 1 condition |
| CC2D2Acoiled-coil and C2 domain containing 2A | Often (30–79%) | In 2 conditions |
| CEP104centrosomal protein 104 | Often (30–79%) | In 1 condition |
| CEP120centrosomal protein 120 | Often (30–79%) | In 2 conditions |
| CEP290centrosomal protein 290 | Often (30–79%) | In 1 condition |
| CEP41centrosomal protein 41 | Often (30–79%) | In 2 conditions |
| CPLANE1ciliogenesis and planar polarity effector complex subunit 1 | Often (30–79%) | In 2 conditions |
| CSPP1centrosome and spindle pole associated protein 1 | Often (30–79%) | In 1 condition |
| DHCR77-dehydrocholesterol reductase | Often (30–79%) | In 1 condition |
| FAM149B1family with sequence similarity 149 member B1 | Often (30–79%) | In 1 condition |
| GATA4GATA binding protein 4 | Often (30–79%) | In 1 condition |
| HYLS1HYLS1 centriolar and ciliogenesis associated | Often (30–79%) | In 1 condition |
| IFT74intraflagellar transport 74 | Often (30–79%) | In 1 condition |
| INPP5Einositol polyphosphate-5-phosphatase E | Often (30–79%) | In 3 conditions |
| KATNIPkatanin interacting protein | Often (30–79%) | In 1 condition |
| KIAA0586KIAA0586 | Often (30–79%) | In 1 condition |
| KIAA0753KIAA0753 | Often (30–79%) | In 2 conditions |
| KIF7kinesin family member 7 | Often (30–79%) | In 1 condition |
| LIG4DNA ligase 4 | Often (30–79%) | In 1 condition |
| MAP2K1mitogen-activated protein kinase kinase 1 | Often (30–79%) | In 1 condition |
| MAP2K2mitogen-activated protein kinase kinase 2 | Often (30–79%) | In 1 condition |
| MEIS2Meis homeobox 2 | Often (30–79%) | In 1 condition |
| MKS1MKS transition zone complex subunit 1 | Often (30–79%) | In 2 conditions |
| NPHP1nephrocystin 1 | Often (30–79%) | In 1 condition |
| OFD1OFD1 centriole and centriolar satellite protein | Often (30–79%) | In 2 conditions |
| PDE6Dphosphodiesterase 6D | Often (30–79%) | In 2 conditions |
| PIBF1progesterone immunomodulatory binding factor 1 | Often (30–79%) | In 1 condition |
Show 24 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| PLK4polo like kinase 4 | Often (30–79%) | In 1 condition |
| RPGRIP1LRPGRIP1 like | Often (30–79%) | In 2 conditions |
| SC5Dsterol-C5-desaturase | Often (30–79%) | In 1 condition |
| SUFUSUFU negative regulator of hedgehog signaling | Often (30–79%) | In 1 condition |
| TCTN1tectonic family member 1 | Often (30–79%) | In 1 condition |
| TCTN2tectonic family member 2 | Often (30–79%) | In 1 condition |
| TCTN3tectonic family member 3 | Often (30–79%) | In 2 conditions |
| TMEM138transmembrane protein 138 | Often (30–79%) | In 1 condition |
| TMEM216transmembrane protein 216 | Often (30–79%) | In 2 conditions |
| TMEM218transmembrane protein 218 | Often (30–79%) | In 1 condition |
| TMEM231transmembrane protein 231 | Often (30–79%) | In 2 conditions |
| TMEM237transmembrane protein 237 | Often (30–79%) | In 3 conditions |
| TMEM67transmembrane protein 67 | Often (30–79%) | In 2 conditions |
| TOGARAM1TOG array regulator of axonemal microtubules 1 | Often (30–79%) | In 1 condition |
| TOPORSTOP1 binding arginine/serine rich protein, E3 ubiquitin ligase | Often (30–79%) | In 1 condition |
| TUBGCP4tubulin gamma complex component 4 | Often (30–79%) | In 1 condition |
| TUBGCP6tubulin gamma complex component 6 | Often (30–79%) | In 1 condition |
| TWIST1twist family bHLH transcription factor 1 | Often (30–79%) | In 1 condition |
| ZNF423zinc finger protein 423 | Often (30–79%) | In 1 condition |
| ANKRD11ankyrin repeat domain 11 | Sometimes (5–29%) | In 1 condition |
| CUL4Bcullin 4B | Sometimes (5–29%) | In 1 condition |
| HNRNPUheterogeneous nuclear ribonucleoprotein U | Sometimes (5–29%) | In 1 condition |
| MCOLN1mucolipin TRP cation channel 1 | Sometimes (5–29%) | In 1 condition |
| PTENphosphatase and tensin homolog | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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