Trait
Pimple
Clinical name: Pustule
A small elevation of the skin containing cloudy or purulent material usually consisting of necrotic inflammatory cells.
Summary
- Also called
- Pustula, Pustular lesion, Pustules, Skin pustule, Skin pustules
Reference genomeGRCh38hg38
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Get my Genome Test44 genes linked to Pimple
Changes in these genes cause rare conditions in which Pimple is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ADAM17ADAM metallopeptidase domain 17 | Always | In 2 conditions |
| AP1S3adaptor related protein complex 1 subunit sigma 3 | Always | In 1 condition |
| DCLRE1CDNA cross-link repair 1C | Always | In 1 condition |
| EGFRepidermal growth factor receptor | Always | In 1 condition |
| IL17RAinterleukin 17 receptor A | Always | In 1 condition |
| IL1RNinterleukin 1 receptor antagonist | Always | In 1 condition |
| IL36RNinterleukin 36 receptor antagonist | Always | In 2 conditions |
| MRTFAmyocardin related transcription factor A | Always | In 1 condition |
| RAG1recombination activating 1 | Always | In 1 condition |
| RAG2recombination activating 2 | Always | In 1 condition |
| SPINK5serine peptidase inhibitor Kazal type 5 | Always | In 1 condition |
| CIB1calcium and integrin binding 1 | Very often (80–99%) | In 1 condition |
| CTSCcathepsin C | Very often (80–99%) | In 1 condition |
| ECM1extracellular matrix protein 1 | Very often (80–99%) | In 1 condition |
| HLA-Bmajor histocompatibility complex, class I, B | Very often (80–99%) | In 2 conditions |
| IL7interleukin 7 | Very often (80–99%) | In 1 condition |
| LPIN2lipin 2 | Very often (80–99%) | In 1 condition |
| PSTPIP1proline-serine-threonine phosphatase interacting protein 1 | Very often (80–99%) | In 1 condition |
| SLC39A4solute carrier family 39 member 4 | Very often (80–99%) | In 1 condition |
| TMC6transmembrane channel like 6 | Very often (80–99%) | In 1 condition |
| TMC8transmembrane channel like 8 | Very often (80–99%) | In 1 condition |
| C4Acomplement C4A (Chido/Rodgers blood group) | Often (30–79%) | In 1 condition |
| CCR1C-C motif chemokine receptor 1 | Often (30–79%) | In 1 condition |
| ERAP1endoplasmic reticulum aminopeptidase 1 | Often (30–79%) | In 1 condition |
| FASFas cell surface death receptor | Often (30–79%) | In 1 condition |
| IFNGR1interferon gamma receptor 1 | Often (30–79%) | In 1 condition |
| IL10interleukin 10 | Often (30–79%) | In 1 condition |
| IL12Ainterleukin 12A | Often (30–79%) | In 1 condition |
| IL12A-AS1IL12A antisense RNA 1 | Often (30–79%) | In 1 condition |
| IL23Rinterleukin 23 receptor | Often (30–79%) | In 1 condition |
| KLRC4killer cell lectin like receptor C4 | Often (30–79%) | In 1 condition |
| LDHAlactate dehydrogenase A | Often (30–79%) | In 1 condition |
| MEFVMEFV innate immunity regulator, pyrin | Often (30–79%) | In 2 conditions |
| STAT4signal transducer and activator of transcription 4 | Often (30–79%) | In 1 condition |
| TLR4toll like receptor 4 | Often (30–79%) | In 1 condition |
| UBAC2UBA domain containing 2 | Often (30–79%) | In 1 condition |
| CARD14caspase recruitment domain family member 14 | Sometimes (5–29%) | In 1 condition |
| CTSBcathepsin B | Sometimes (5–29%) | In 1 condition |
| JAK3Janus kinase 3 | Sometimes (5–29%) | In 1 condition |
| PTPN6protein tyrosine phosphatase non-receptor type 6 | Sometimes (5–29%) | In 1 condition |
Show 4 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| SCNN1Asodium channel epithelial 1 subunit alpha | Sometimes (5–29%) | In 1 condition |
| SCNN1Bsodium channel epithelial 1 subunit beta | Sometimes (5–29%) | In 1 condition |
| SCNN1Gsodium channel epithelial 1 subunit gamma | Sometimes (5–29%) | In 1 condition |
| STING1stimulator of interferon response cGAMP interactor 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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